Q608L4 (GLGA1_METCA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycogen synthase 1
EC=2.4.1.21

Alternative name(s):
Starch [bacterial glycogen] synthase 1

Gene names

Name:	glgA1
Ordered Locus Names:	MCA1476

Organism

Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath) [Complete proteome] [HAMAP]

Taxonomic identifier

243233 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Methylococcales › Methylococcaceae › Methylococcus › Methylococcus capsulatus

Protein attributes

Sequence length	493 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Synthesizes alpha-1,4-glucan chains using ADP-glucose By similarity. HAMAP-Rule MF_00484
Catalytic activity	ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP-Rule MF_00484
Pathway	Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00484
Sequence similarities	Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Ontologies

Keywords
Biological process	Glycogen biosynthesis
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glycogen biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	starch synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 493	493	Glycogen synthase 1 HAMAP-Rule MF_00484		PRO_0000230245
Sites
	Binding site	15	1	ADP-glucose By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q608L4 [UniParc]. Last modified November 23, 2004. Version 1. Checksum: 2180CEFF91B11266	FASTA	493	53,815
	10 20 30 40 50 60 MKILFVSSEV FPLMKTGGLA DVSGSLPAAL SALGHDVRIL MPAYPEAISA AETPNALSLR 70 80 90 100 110 120 QAGSQLTLLS TRLPGTTVPL WLLDAPASFG RFGNPYLAPN GAPWPDNAER FALLARVAVD 130 140 150 160 170 180 LTQDRLGLGW KPDVVHCNDW QTGLIPPLLS DEPNRPAVVF TVHNLAYQGL FPYETFQRLA 190 200 210 220 230 240 LPPRLWKMEA LEFYGQLSFI KGGLVFADRI NTVSPSYAEE IQTPEFGCGL DGLLRSRKSC 250 260 270 280 290 300 LSGILNGIDD VAWNPATDPY LPAPYGPDTL ERKKVNRTVL RQRYGLPDDP EVAVLGMVGR 310 320 330 340 350 360 MVEQKGVDLL IDILDDLLQL PVQLVVLGSG DKEFERCFER AAAARPERIA VTIGYDEPLA 370 380 390 400 410 420 HLIEAGADIF LMPSRFEPCG LNQLYSQRYG TVPIVRKVGG LADTVEDATP ERLAAGQASG 430 440 450 460 470 480 IVFEPAKPAF LLEAVYRALA LYREPEVWRA VCKCGMAKDF SWRKSASRYV GLYREALAGM 490 NAGCSIADPR CAA

References

[1]

"Genomic insights into methanotrophy: the complete genome sequence of Methylococcus capsulatus (Bath)." Ward N.L., Larsen O., Sakwa J., Bruseth L., Khouri H.M., Durkin A.S., Dimitrov G., Jiang L., Scanlan D., Kang K.H., Lewis M.R., Nelson K.E., Methe B.A., Wu M., Heidelberg J.F., Paulsen I.T., Fouts D.E., Ravel J. , Tettelin H., Ren Q., Read T.D., DeBoy R.T., Seshadri R., Salzberg S.L., Jensen H.B., Birkeland N.K., Nelson W.C., Dodson R.J., Grindhaug S.H., Holt I.E., Eidhammer I., Jonasen I., Vanaken S., Utterback T.R., Feldblyum T.V., Fraser C.M., Lillehaug J.R., Eisen J.A. PLoS Biol. 2:1616-1628(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33009 / NCIMB 11132 / Bath.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017282 Genomic DNA. Translation: AAU92508.1.
RefSeq	YP_113933.1. NC_002977.6.
3D structure databases
ProteinModelPortal	Q608L4.
ModBase	Search...
Protein-protein interaction databases
STRING	243233.MCA1476.
Protein family/group databases
CAZy	GT5. Glycosyltransferase Family 5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAU92508; AAU92508; MCA1476.
GeneID	3104785.
KEGG	mca:MCA1476.
PATRIC	22606788. VBIMetCap22254_1506.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0297.
HOGENOM	HOG000294941.
KO	K00703.
OMA	ERYPQNI.
Enzyme and pathway databases
UniPathway	UPA00164.
Family and domain databases
HAMAP	MF_00484. Glycogen_synth.
InterPro	IPR001296. Glyco_trans_1. IPR011835. Glycogen/starch_synth. IPR013534. Starch_synth_cat_dom. [Graphical view]
Pfam	PF08323. Glyco_transf_5. 1 hit. PF00534. Glycos_transf_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR02095. glgA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLGA1_METCA

Accession

Primary (citable) accession number: Q608L4

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 4, 2006
Last sequence update:	November 23, 2004
Last modified:	May 1, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program