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Protein

Olfactory receptor 148

Gene

Olfr148

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Odorant receptor.Curated

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptor, Receptor, Transducer

Keywords - Biological processi

Olfaction, Sensory transduction

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptor 148
Alternative name(s):
Odorant receptor M30
Olfactory receptor 224-4
Olfactory receptor 7F
Gene namesi
Name:Olfr148
Synonyms:Mor224-4, Olfr7
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:2660713. Olfr148.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 23ExtracellularSequence analysisAdd BLAST23
Transmembranei24 – 44Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini45 – 55CytoplasmicSequence analysisAdd BLAST11
Transmembranei56 – 76Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini77 – 95ExtracellularSequence analysisAdd BLAST19
Transmembranei96 – 116Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini117 – 136CytoplasmicSequence analysisAdd BLAST20
Transmembranei137 – 157Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini158 – 202ExtracellularSequence analysisAdd BLAST45
Transmembranei203 – 223Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini224 – 237CytoplasmicSequence analysisAdd BLAST14
Transmembranei238 – 258Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini259 – 264ExtracellularSequence analysis6
Transmembranei265 – 285Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini286 – 310CytoplasmicSequence analysisAdd BLAST25

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001508251 – 310Olfactory receptor 148Add BLAST310

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi3N-linked (GlcNAc...)Sequence analysis1
Disulfide bondi95 ↔ 187PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ60887.
PRIDEiQ60887.

PTM databases

iPTMnetiQ60887.
PhosphoSitePlusiQ60887.

Expressioni

Gene expression databases

BgeeiENSMUSG00000048299.
CleanExiMM_OLFR148.
ExpressionAtlasiQ60887. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000096473.

Structurei

3D structure databases

ProteinModelPortaliQ60887.
SMRiQ60887.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410J8RB. Eukaryota.
ENOG41113Y5. LUCA.
GeneTreeiENSGT00760000119161.
HOGENOMiHOG000041362.
HOVERGENiHBG017625.
InParanoidiQ60887.
KOiK04257.
OMAiCLHATIL.
OrthoDBiEOG091G0E8U.
PhylomeDBiQ60887.
TreeFamiTF336512.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q60887-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDNYTLLNEF ILLGIPQTQG LETLLFVVFL FIYFFTLLGN SLIFTAIISS
60 70 80 90 100
STLHTPMYFF LGLLSVFDML FPSVTCPKML FYLSVRSPAI SYKGCAAQLF
110 120 130 140 150
FYHLLGSTEG CLYSVMAYDR YVAICHPLRY MLIMKPGVCV SLVIIAWLVG
160 170 180 190 200
CLHATILTSL TFQLVYCASN QVDYFFCDLP AVLPLACTDS KLARKVGSIN
210 220 230 240 250
VGFLALMLLF SVCVSYVHIG VAILRIRSAE GRQKAFSTCS AHLTAILCAY
260 270 280 290 300
GPVIIIYLQR TPNPLLGAVV QILNNIVSPM LNSLIYSLRN KEVKRSLRRV
310
FQNITFHGQK
Length:310
Mass (Da):34,662
Last modified:January 24, 2006 - v2
Checksum:iEBABBD625F57C96F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF282301 Genomic DNA. Translation: AAG39886.1.
AY073592 Genomic DNA. Translation: AAL61255.1.
AY318151 Genomic DNA. Translation: AAP71423.1.
U28776 Genomic DNA. Translation: AAC52399.1.
CCDSiCCDS23053.1.
RefSeqiNP_666716.1. NM_146505.1.
UniGeneiMm.377537.

Genome annotation databases

EnsembliENSMUST00000050807; ENSMUSP00000096473; ENSMUSG00000048299.
GeneIDi258498.
KEGGimmu:258498.
UCSCiuc009oyg.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF282301 Genomic DNA. Translation: AAG39886.1.
AY073592 Genomic DNA. Translation: AAL61255.1.
AY318151 Genomic DNA. Translation: AAP71423.1.
U28776 Genomic DNA. Translation: AAC52399.1.
CCDSiCCDS23053.1.
RefSeqiNP_666716.1. NM_146505.1.
UniGeneiMm.377537.

3D structure databases

ProteinModelPortaliQ60887.
SMRiQ60887.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000096473.

Protein family/group databases

GPCRDBiSearch...

PTM databases

iPTMnetiQ60887.
PhosphoSitePlusiQ60887.

Proteomic databases

PaxDbiQ60887.
PRIDEiQ60887.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000050807; ENSMUSP00000096473; ENSMUSG00000048299.
GeneIDi258498.
KEGGimmu:258498.
UCSCiuc009oyg.1. mouse.

Organism-specific databases

CTDi258498.
MGIiMGI:2660713. Olfr148.

Phylogenomic databases

eggNOGiENOG410J8RB. Eukaryota.
ENOG41113Y5. LUCA.
GeneTreeiENSGT00760000119161.
HOGENOMiHOG000041362.
HOVERGENiHBG017625.
InParanoidiQ60887.
KOiK04257.
OMAiCLHATIL.
OrthoDBiEOG091G0E8U.
PhylomeDBiQ60887.
TreeFamiTF336512.

Miscellaneous databases

PROiQ60887.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000048299.
CleanExiMM_OLFR148.
ExpressionAtlasiQ60887. baseline and differential.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiOL148_MOUSE
AccessioniPrimary (citable) accession number: Q60887
Secondary accession number(s): Q9EQ88
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: January 24, 2006
Last modified: November 2, 2016
This is version 120 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.