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Q606J5

- PGK_METCA

UniProt

Q606J5 - PGK_METCA

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Protein
Phosphoglycerate kinase
Gene
pgk, MCA2021
Organism
Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei36 – 361Substrate By similarity
Binding sitei113 – 1131Substrate By similarity
Binding sitei146 – 1461Substrate By similarity
Binding sitei197 – 1971ATP By similarity
Binding sitei319 – 3191ATP By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi345 – 3484ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:pgk
Ordered Locus Names:MCA2021
OrganismiMethylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)
Taxonomic identifieri243233 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaMethylococcalesMethylococcaceaeMethylococcus
ProteomesiUP000006821: Chromosome

Subcellular locationi

Cytoplasm Reviewed prediction UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 391391Phosphoglycerate kinaseUniRule annotation
PRO_1000058014Add
BLAST

Proteomic databases

PRIDEiQ606J5.

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi243233.MCA2021.

Structurei

3D structure databases

ProteinModelPortaliQ606J5.
SMRiQ606J5. Positions 5-390.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni21 – 233Substrate binding By similarity
Regioni59 – 624Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227107.
KOiK00927.
OMAiAGHPVGK.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q606J5-1 [UniParc]FASTAAdd to Basket

« Hide

MAFKRMTDID LAGKRVLIRE DFNVPVKDGR VTSDARIRAA LPTIRHALDA    50
GAAVMLMSHL GRPTEGEYAE EFSMKPVADR LSELLGQPVT LVKDYLGGAD 100
PAVGSVVLFE NVRFNKGEKK DDEVLARQLA ALCDVYVMDA FGTAHRAEAS 150
THGVGKYAPT ACAGLLLATE LDALGRALHD PARPLVAIVG GSKVSTKLTV 200
LDSLSQVVDQ LIVGGGIANT FIKAAGFNVG KSLYEEDLVA EARRLMEAAK 250
AKGGEIPVPV DVVVGKRFDA AEPAMVKSVA DIAEDDMILD IGPETSRRYA 300
EFIGRAGTVV WNGPVGVFEF DQFGEGTRRL GLAIAESHAF SIAGGGDTLA 350
AIDKYGIADR ISYISTGGGA FLEFLEGKQL PAVAMLESRA D 391
Length:391
Mass (Da):41,462
Last modified:November 23, 2004 - v1
Checksum:i163CE0C30FF3FAD3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017282 Genomic DNA. Translation: AAU91741.1.
RefSeqiWP_010961266.1. NC_002977.6.
YP_114453.1. NC_002977.6.

Genome annotation databases

EnsemblBacteriaiAAU91741; AAU91741; MCA2021.
GeneIDi3104829.
KEGGimca:MCA2021.
PATRICi22607892. VBIMetCap22254_2053.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017282 Genomic DNA. Translation: AAU91741.1 .
RefSeqi WP_010961266.1. NC_002977.6.
YP_114453.1. NC_002977.6.

3D structure databases

ProteinModelPortali Q606J5.
SMRi Q606J5. Positions 5-390.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243233.MCA2021.

Proteomic databases

PRIDEi Q606J5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAU91741 ; AAU91741 ; MCA2021 .
GeneIDi 3104829.
KEGGi mca:MCA2021.
PATRICi 22607892. VBIMetCap22254_2053.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227107.
KOi K00927.
OMAi AGHPVGK.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33009 / NCIMB 11132 / Bath.

Entry informationi

Entry nameiPGK_METCA
AccessioniPrimary (citable) accession number: Q606J5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 23, 2004
Last modified: September 3, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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