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Q60611

- SATB1_MOUSE

UniProt

Q60611 - SATB1_MOUSE

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Protein
DNA-binding protein SATB1
Gene
Satb1
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Required for the switching of fetal globin species, and beta- and gamma-globin genes regulation during erythroid differentiation. Plays a role in chromatin organization and nuclear architecture during apoptosis By similarity. Crucial silencing factor contributing to the initiation of X inactivation mediated by Xist RNA that occurs during embryogenesis and in lymphoma. Binds to DNA at special AT-rich sequences, the consensus SATB1-binding sequence (CSBS), at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcriptional repressor controlling nuclear and viral gene expression in a phosphorylated and acetylated status-dependent manner, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Modulates genes that are essential in the maturation of the immune T-cell CD8SP from thymocytes.9 Publications

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei254 – 2552Cleavage; by caspases
Binding sitei390 – 3901Matrix attachment region (MAR) DNA By similarity
Binding sitei425 – 4251Matrix attachment region (MAR) DNA By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi361 – 44888CUT 1
Add
BLAST
DNA bindingi484 – 57188CUT 2
Add
BLAST
DNA bindingi646 – 70560Homeobox
Add
BLAST

GO - Molecular functioni

  1. DNA binding Source: MGI
  2. chromatin binding Source: MGI
  3. sequence-specific DNA binding Source: InterPro
  4. sequence-specific DNA binding transcription factor activity Source: MGI
Complete GO annotation...

GO - Biological processi

  1. CD4-positive, alpha-beta T cell differentiation Source: MGI
  2. CD8-positive, alpha-beta T cell differentiation Source: MGI
  3. T cell activation Source: MGI
  4. activated T cell proliferation Source: MGI
  5. chromatin organization Source: MGI
  6. chromatin remodeling Source: MGI
  7. epidermis development Source: MGI
  8. histone methylation Source: MGI
  9. negative regulation of transcription from RNA polymerase II promoter Source: MGI
  10. reflex Source: MGI
  11. regulation of transcription, DNA-templated Source: MGI
  12. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Chromatin regulator, Repressor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

ReactomeiREACT_224460. Apoptotic cleavage of cellular proteins.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-binding protein SATB1
Alternative name(s):
Special AT-rich sequence-binding protein 1
Gene namesi
Name:Satb1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 17

Organism-specific databases

MGIiMGI:105084. Satb1.

Subcellular locationi

Nucleus. NucleusPML body
Note: Organized into a cage-like network anchoring loops of heterochromatin and tethering specialized DNA sequences. When sumoylated, localized in promyelocytic leukemia nuclear bodies (PML NBs) By similarity.2 Publications

GO - Cellular componenti

  1. PML body Source: UniProtKB-SubCell
  2. chromatin Source: MGI
  3. nuclear heterochromatin Source: MGI
  4. nuclear matrix Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Disruption phenotypei

Mice are small in size, have disproportionately small thymi and spleens, and die at 3 weeks of age. Multiple defects in T-cell development are observed, including interrupted thymocytes differentiation and abnormal T-cell transcriptome.2 Publications

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 764764DNA-binding protein SATB1
PRO_0000202399Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei136 – 1361N6-acetyllysine By similarity
Modified residuei185 – 1851Phosphoserine By similarity
Cross-linki745 – 745Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) By similarity

Post-translational modificationi

Sumoylated By similarity. Sumoylation promotes cleavage by caspases By similarity.
Phosphorylated by PKC. Acetylated by PCAF. Phosphorylated form interacts with HDAC1, but unphosphorylated form interacts with PCAF. DNA binding properties are activated by phosphorylation and inactivated by acetylation. In opposition, gene expression is down-regulated by phosphorylation but up-regulated by acetylation By similarity.
Cleaved at Asp-254 by caspase-3 and caspase-6 during T-cell apoptosis in thymus and during B-cell stimulation. The cleaved forms can not dimerize and lose transcription regulation function because of impaired DNA and chromatin association.1 Publication

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

MaxQBiQ60611.
PaxDbiQ60611.
PRIDEiQ60611.

PTM databases

PhosphoSiteiQ60611.

Expressioni

Tissue specificityi

Mainly expressed in thymus, spleen, and lymph nodes with a lower level observed in the brain.1 Publication

Gene expression databases

ArrayExpressiQ60611.
BgeeiQ60611.
CleanExiMM_SATB1.
GenevestigatoriQ60611.

Interactioni

Subunit structurei

Interacts with PCAF. Interacts with sumoylated PML and HDAC1 Tat via the PDZ-like dimerization domain. Interacts also with DYNLT3 and POLR2J2. Binds to EP300 By similarity. Homodimer. Part of the nuclear protein complex gamma-globin promoter and enhancer binding factor (gamma-PE) composed at least of SATB1 and HOXB2. Interaction with CtBP1 when not acetylated stabalizes attachment to DNA and promotes transcription repression. Interacts with CUX1 (via DNA-binding domains); the interaction inhibits the attachment of both proteins to DNA.3 Publications

Protein-protein interaction databases

BioGridi203077. 1 interaction.

Structurei

3D structure databases

ProteinModelPortaliQ60611.
SMRiQ60611. Positions 71-171, 179-250, 370-452, 486-573, 647-705.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni90 – 204115PDZ-like dimerization domain
Add
BLAST
Regioni224 – 27855Nuclear matrix targeting sequence (NMTS) By similarity
Add
BLAST
Regioni400 – 41011Matrix attachment region (MAR) DNA-binding By similarity
Add
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi20 – 4021Nuclear localization signal By similarity
Add
BLAST
Motifi139 – 1435Protein interaction By similarity
Motifi224 – 27855Nuclear matrix targeting sequence (NMTS)
Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi591 – 60717Poly-Gln
Add
BLAST
Compositional biasi608 – 61710Poly-Pro

Sequence similaritiesi

Belongs to the CUT homeobox family.

Keywords - Domaini

Homeobox, Repeat

Phylogenomic databases

eggNOGiNOG313826.
GeneTreeiENSGT00390000008096.
HOGENOMiHOG000004805.
HOVERGENiHBG054240.
InParanoidiQ91XB1.
OrthoDBiEOG7FBRH5.
PhylomeDBiQ60611.
TreeFamiTF332714.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.260.40. 2 hits.
InterProiIPR003350. Hmoeo_CUT.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
[Graphical view]
PfamiPF02376. CUT. 2 hits.
PF00046. Homeobox. 1 hit.
[Graphical view]
SMARTiSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 2 hits.
PROSITEiPS51042. CUT. 2 hits.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q60611-1 [UniParc]FASTAAdd to Basket

« Hide

MDHLNEATQG KEHSEMSNNV SDPKGPPAKI ARLEQNGSPL GRGRLGSTGG    50
KMQGVPLKHS GHLMKTNLRK GTMLPVFCVV EHYENAIEYD CKEEHAEFVL 100
VRKDMLFNQL IEMALLSLGY SHSSAAQAKG LIQVGKWNPV PLSYVTDAPD 150
ATVADMLQDV YHVVTLKIQL HSCPKLEDLP PEQWSHTTVR NALKDLLKDM 200
NQSSLAKECP LSQSMISSIV NSTYYANVSA AKCQEFGRWY KHFKKTKDMM 250
VEMDSLSELS QQGANHVNFG QQPVPGNTAE QPPSPAQLSH GSQPSVRTPL 300
PNLHPGLVST PISPQLVNQQ LVMAQLLNQQ YAVNRLLAQQ SLNQQYLNHP 350
PPVSRSMNKP LEQQVSTNTE VSSEIYQWVR DELKRAGISQ AVFARVAFNR 400
TQGLLSEILR KEEDPKTASQ SLLVNLRAMQ NFLQLPEAER DRIYQDERER 450
SLNAASAMGP APLLSTPPSR PPQVKTATLA TERNGKPENN TMNINASIYD 500
EIQQEMKRAK VSQALFAKVA ATKSQGWLCE LLRWKEDPSP ENRTLWENLS 550
MIRRFLSLPQ PERDAIYEQE SNAVHHHGDR PPHIIHVPAE QIQQQQQQQQ 600
QQQQQQQPPP PPPQPQPQPQ AGPRLPPRQP TVASSAESDE ENRQKTRPRT 650
KISVEALGIL QSFIQDVGLY PDEEAIQTLS AQLDLPKYTI IKFFQNQRYY 700
LKHHGKLKDN SGLEVDVAEY KDEELLKDLE ESVQDKNANT LFSVKLEEEL 750
SVEGSTDVNA DLKD 764
Length:764
Mass (Da):85,880
Last modified:July 27, 2011 - v2
Checksum:i330ECCDBA8683B78
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti155 – 1551D → N in AAA17372. 1 Publication
Sequence conflicti515 – 5151L → P in AAA17372. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U05252 mRNA. Translation: AAA17372.1.
AK088563 mRNA. Translation: BAC40427.1.
AK158518 mRNA. Translation: BAE34542.1.
CT010371 mRNA. Translation: CAJ18578.1.
BC011132 mRNA. Translation: AAH11132.1.
CH466559 Genomic DNA. Translation: EDL23652.1.
CCDSiCCDS28876.1.
PIRiA56208.
RefSeqiNP_001157102.1. NM_001163630.1.
NP_001157103.1. NM_001163631.1.
NP_001157104.1. NM_001163632.1.
NP_033148.2. NM_009122.2.
UniGeneiMm.311655.

Genome annotation databases

EnsembliENSMUST00000133574; ENSMUSP00000120536; ENSMUSG00000023927.
ENSMUST00000144331; ENSMUSP00000116006; ENSMUSG00000023927.
ENSMUST00000152830; ENSMUSP00000119842; ENSMUSG00000023927.
ENSMUST00000169480; ENSMUSP00000128841; ENSMUSG00000023927.
ENSMUST00000176669; ENSMUSP00000134957; ENSMUSG00000023927.
GeneIDi20230.
KEGGimmu:20230.
UCSCiuc008czd.2. mouse.

Keywords - Coding sequence diversityi

Chromosomal rearrangement

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U05252 mRNA. Translation: AAA17372.1 .
AK088563 mRNA. Translation: BAC40427.1 .
AK158518 mRNA. Translation: BAE34542.1 .
CT010371 mRNA. Translation: CAJ18578.1 .
BC011132 mRNA. Translation: AAH11132.1 .
CH466559 Genomic DNA. Translation: EDL23652.1 .
CCDSi CCDS28876.1.
PIRi A56208.
RefSeqi NP_001157102.1. NM_001163630.1.
NP_001157103.1. NM_001163631.1.
NP_001157104.1. NM_001163632.1.
NP_033148.2. NM_009122.2.
UniGenei Mm.311655.

3D structure databases

ProteinModelPortali Q60611.
SMRi Q60611. Positions 71-171, 179-250, 370-452, 486-573, 647-705.
ModBasei Search...

Protein-protein interaction databases

BioGridi 203077. 1 interaction.

PTM databases

PhosphoSitei Q60611.

Proteomic databases

MaxQBi Q60611.
PaxDbi Q60611.
PRIDEi Q60611.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000133574 ; ENSMUSP00000120536 ; ENSMUSG00000023927 .
ENSMUST00000144331 ; ENSMUSP00000116006 ; ENSMUSG00000023927 .
ENSMUST00000152830 ; ENSMUSP00000119842 ; ENSMUSG00000023927 .
ENSMUST00000169480 ; ENSMUSP00000128841 ; ENSMUSG00000023927 .
ENSMUST00000176669 ; ENSMUSP00000134957 ; ENSMUSG00000023927 .
GeneIDi 20230.
KEGGi mmu:20230.
UCSCi uc008czd.2. mouse.

Organism-specific databases

CTDi 6304.
MGIi MGI:105084. Satb1.

Phylogenomic databases

eggNOGi NOG313826.
GeneTreei ENSGT00390000008096.
HOGENOMi HOG000004805.
HOVERGENi HBG054240.
InParanoidi Q91XB1.
OrthoDBi EOG7FBRH5.
PhylomeDBi Q60611.
TreeFami TF332714.

Enzyme and pathway databases

Reactomei REACT_224460. Apoptotic cleavage of cellular proteins.

Miscellaneous databases

ChiTaRSi SATB1. mouse.
NextBioi 297861.
PROi Q60611.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q60611.
Bgeei Q60611.
CleanExi MM_SATB1.
Genevestigatori Q60611.

Family and domain databases

Gene3Di 1.10.10.60. 1 hit.
1.10.260.40. 2 hits.
InterProi IPR003350. Hmoeo_CUT.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
[Graphical view ]
Pfami PF02376. CUT. 2 hits.
PF00046. Homeobox. 1 hit.
[Graphical view ]
SMARTi SM00389. HOX. 1 hit.
[Graphical view ]
SUPFAMi SSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 2 hits.
PROSITEi PS51042. CUT. 2 hits.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "A novel DNA-binding motif in the nuclear matrix attachment DNA-binding protein SATB1."
    Nakagomi K., Kohwi Y., Dickinson L.A., Kohwi-Shigematsu T.
    Mol. Cell. Biol. 14:1852-1860(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Thymus.
  2. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J and NOD.
    Tissue: Thymus and Visual cortex.
  3. "Cloning of mouse full open reading frames in Gateway(R) system entry vector (pDONR201)."
    Ebert L., Muenstermann E., Schatten R., Henze S., Bohn E., Mollenhauer J., Wiemann S., Schick M., Korn B.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  4. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: FVB/N.
    Tissue: Salivary gland.
  6. "SATB1 cleavage by caspase 6 disrupts PDZ domain-mediated dimerization, causing detachment from chromatin early in T-cell apoptosis."
    Galande S., Dickinson L.A., Mian I.S., Sikorska M., Kohwi-Shigematsu T.
    Mol. Cell. Biol. 21:5591-5604(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 255-259, FUNCTION, DIMERIZATION, CLEAVAGE BY CASP6.
  7. "The matrix attachment region-binding protein SATB1 participates in negative regulation of tissue-specific gene expression."
    Liu J., Bramblett D., Zhu Q., Lozano M., Kobayashi R., Ross S.R., Dudley J.P.
    Mol. Cell. Biol. 17:5275-5287(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  8. "Homeoproteins CDP and SATB1 interact: potential for tissue-specific regulation."
    Liu J., Barnett A., Neufeld E.J., Dudley J.P.
    Mol. Cell. Biol. 19:4918-4926(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH CUX1.
  9. "The MAR-binding protein SATB1 orchestrates temporal and spatial expression of multiple genes during T-cell development."
    Alvarez J.D., Yasui D.H., Niida H., Joh T., Loh D.Y., Kohwi-Shigematsu T.
    Genes Dev. 14:521-535(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, DISRUPTION PHENOTYPE.
  10. "Tissue-specific nuclear architecture and gene expression regulated by SATB1."
    Cai S., Han H.-J., Kohwi-Shigematsu T.
    Nat. Genet. 34:42-51(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION.
  11. "Nuclear matrix binding regulates SATB1-mediated transcriptional repression."
    Seo J., Lozano M.M., Dudley J.P.
    J. Biol. Chem. 280:24600-24609(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION, NUCLEAR MATRIX TARGETING SEQUENCE.
  12. "A role for SATB1, a nuclear matrix association region-binding protein, in the development of CD8SP thymocytes and peripheral T lymphocytes."
    Nie H., Maika S.D., Tucker P.W., Gottlieb P.D.
    J. Immunol. 174:4745-4752(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, DISRUPTION PHENOTYPE, TISSUE SPECIFICITY.
  13. "SATB1 packages densely looped, transcriptionally active chromatin for coordinated expression of cytokine genes."
    Cai S., Lee C.C., Kohwi-Shigematsu T.
    Nat. Genet. 38:1278-1288(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  14. "SATB1 is required for CD8 coreceptor reversal."
    Nie H., Yao X., Maika S.D., Tucker P.W.
    Mol. Immunol. 46:207-211(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  15. "SATB1 defines the developmental context for gene silencing by Xist in lymphoma and embryonic cells."
    Agrelo R., Souabni A., Novatchkova M., Haslinger C., Leeb M., Komnenovic V., Kishimoto H., Gresh L., Kohwi-Shigematsu T., Kenner L., Wutz A.
    Dev. Cell 16:507-516(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  16. "Acetylation-dependent interaction of SATB1 and CtBP1 mediates transcriptional repression by SATB1."
    Purbey P.K., Singh S., Notani D., Kumar P.P., Limaye A.S., Galande S.
    Mol. Cell. Biol. 29:1321-1337(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, INTERACTION WITH CTBP1.

Entry informationi

Entry nameiSATB1_MOUSE
AccessioniPrimary (citable) accession number: Q60611
Secondary accession number(s): Q91XB1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: July 27, 2011
Last modified: September 3, 2014
This is version 128 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi