Reviewed, UniProtKB/Swiss-Prot Q60597 (ODO1_MOUSE)

Names and origin

Protein names

Recommended name:
    2-oxoglutarate dehydrogenase E1 component, mitochondrial
    EC=1.2.4.2
Alternative name(s):
    Alpha-ketoglutarate dehydrogenase

Gene names

Name:	Ogdh
Synonyms:	Kiaa4192

Organism

Mus musculus (Mouse)

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	1023 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).
Catalytic activity	2-oxoglutarate + [dihydrolipoyllysine-residue succinyltransferase] lipoyllysine = [dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine + CO(2).
Cofactor	Thiamine pyrophosphate.
Enzyme regulation	Catabolite repressed.
Subcellular location	Mitochondrion matrix.
Sequence similarities	Belongs to the alpha-ketoglutarate dehydrogenase family.

Ontologies

Keywords
Biological process	Glycolysis
Cellular component	Mitochondrion
Coding sequence diversity	Alternative splicing
Domain	Transit peptide
Ligand	Thiamine pyrophosphate
Molecular function	Oxidoreductase
PTM	Ubl conjugation
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: InterPro oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	mitochondrial matrix Inferred from electronic annotation. Source: UniProtKB-SubCell mitochondrial membrane Inferred from sequence or structural similarity. Source: UniProtKB
Molecular function	oxoglutarate dehydrogenase (NAD+) activity Inferred from direct assay. Source: MGI oxoglutarate dehydrogenase (succinyl-transferring) activity Inferred from sequence or structural similarity. Source: UniProtKB thiamin pyrophosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Alternative products

This entry describes 4 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q60597-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Notes: No experimental confirmation available.

Isoform 2 (identifier: Q60597-2)

The sequence of this isoform differs from the canonical sequence as follows:
     139-172: IRGHHVAQLDPLGILDADLDSSVPADIISSTDKL → VRGHHIAKSCVNFDDAPVTVSSNV

Isoform 3 (identifier: Q60597-3)

The sequence of this isoform differs from the canonical sequence as follows:
     172-172: L → LDLAVFKERLRMLTVG

Notes: No experimental confirmation available.

Isoform 4 (identifier: Q60597-4)

The sequence of this isoform differs from the canonical sequence as follows:
     139-172: IRGHHVAQLDPLGILDADLDSSVPADIISSTDKL → VRGHHIAKLD...KERLRMLTVG

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – 40	40	Mitochondrion By similarity
	Chain	41 – 1023	983	2-oxoglutarate dehydrogenase E1 component, mitochondrial		PRO_0000020434
Regions
	Region	933 – 939	7	Recognized by alloreactive CD8 cytotoxic T-lymphocytes in association with a class I MHC protein
Amino acid modifications
	Cross-link	534		Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) By similarity
Natural variations
	Alternative sequence	139 – 172	34	IRGHH…STDKL → VRGHHIAKSCVNFDDAPVTV SSNV in isoform 2.		VSP_024799
	Alternative sequence	139 – 172	34	IRGHH…STDKL → VRGHHIAKLDPLGISCVNFD DAPVTVSSNVDLAVFKERLR MLTVG in isoform 4.		VSP_024800
	Alternative sequence	172	1	L → LDLAVFKERLRMLTVG in isoform 3.		VSP_024801
Experimental info
	Sequence conflict	416	1	G → V in AAH49104. Ref.4
	Sequence conflict	549	1	V → F in AAH49104. Ref.4
	Sequence conflict	552	1	Q → E in AAH57354. Ref.4
	Sequence conflict	576	1	E → K in BAE29234. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified May 1, 2007. Version 3. Checksum: A0F3F8D36C7A76BC	FASTA	1,023	116,449
	10 20 30 40 50 60 MFHLRTCAAK LRPLTASQTV KTFSQNKPAA IRTFQQIRCY SAPVAAEPFL SGTSSNYVEE 70 80 90 100 110 120 MYCAWLENPK SVHKSWDIFF RNTNAGAPPG TAYQSPLSLS RSSLATMAHA QSLVEAQPNV 130 140 150 160 170 180 DKLVEDHLAV QSLIRAYQIR GHHVAQLDPL GILDADLDSS VPADIISSTD KLGFYGLHES 190 200 210 220 230 240 DLDKVFHLPT TTFIGGQEPA LPLREIIRRL EMAYCQHIGV EFMFINDLEQ CQWIRQKFET 250 260 270 280 290 300 PGIMQFTNEE KRTLLARLVR STRFEEFLQR KWSSEKRFGL EGCEVLIPAL KTIIDMSSAN 310 320 330 340 350 360 GVDYVIMGMP HRGRLNVLAN VIRKELEQIF CQFDSKLEAA DEGSGDMKYH LGMYHRRINR 370 380 390 400 410 420 VTDRNITLSL VANPSHLEAA DPVVMGKTKA EQFYCGDTEG KKVMSILLHG DAAFAGQGIV 430 440 450 460 470 480 YETFHLSDLP SYTTHGTVHV VVNNQIGFTT DPRMARSSPY PTDVARVVNA PIFHVNSDDP 490 500 510 520 530 540 EAVMYVCKVA AEWRNTFHKD VVVDLVCYRR NGHNEMDEPM FTQPLMYKQI RKQKPVLQKY 550 560 570 580 590 600 AELLVSQGVV NQPEYEEEIS KYDKICEEAF TRSKDEKILH IKHWLDSPWP GFFTLDGQPR 610 620 630 640 650 660 SMTCPSTGLE EDVLFHIGKV ASSVPVENFT IHGGLSRILK TRRELVTNRT VDWALAEYMA 670 680 690 700 710 720 FGSLLKEGIH VRLSGQDVER GTFSHRHHVL HDQNVDKRTC IPMNHLWPNQ APYTVCNSSL 730 740 750 760 770 780 SEYGVLGFEL GFAMASPNAL VLWEAQFGDF NNMAQCIIDQ FICPGQAKWV RQNGIVLLLP 790 800 810 820 830 840 HGMEGMGPEH SSARPERFLQ MCNDDPDVLP DLQEENFDIN QLYDCNWIVV NCSTPGNFFH 850 860 870 880 890 900 VLRRQILLPF RKPLIVFTPK SLLRHPEART SFDEMLPGTH FQRVIPENGP AAQDPHKVKR 910 920 930 940 950 960 LLFCTGKVYY DLTRERKARN MEEEVAITRI EQLSPFPFDL LLKEAQKYPN AELAWCQEEH 970 980 990 1000 1010 1020 KNQGYYDYVK PRLRTTIDRA KPVWYAGRDP AAAPATGNKK THLTELQRFL DTAFDLDAFK KFS
	Isoform 2 [UniParc]. Checksum: 64CBC6F0E46B5D5F		1,013	115,419
	10 20 30 40 50 60 MFHLRTCAAK LRPLTASQTV KTFSQNKPAA IRTFQQIRCY SAPVAAEPFL SGTSSNYVEE 70 80 90 100 110 120 MYCAWLENPK SVHKSWDIFF RNTNAGAPPG TAYQSPLSLS RSSLATMAHA QSLVEAQPNV 130 140 150 160 170 180 DKLVEDHLAV QSLIRAYQVR GHHIAKSCVN FDDAPVTVSS NVGFYGLHES DLDKVFHLPT 190 200 210 220 230 240 TTFIGGQEPA LPLREIIRRL EMAYCQHIGV EFMFINDLEQ CQWIRQKFET PGIMQFTNEE 250 260 270 280 290 300 KRTLLARLVR STRFEEFLQR KWSSEKRFGL EGCEVLIPAL KTIIDMSSAN GVDYVIMGMP 310 320 330 340 350 360 HRGRLNVLAN VIRKELEQIF CQFDSKLEAA DEGSGDMKYH LGMYHRRINR VTDRNITLSL 370 380 390 400 410 420 VANPSHLEAA DPVVMGKTKA EQFYCGDTEG KKVMSILLHG DAAFAGQGIV YETFHLSDLP 430 440 450 460 470 480 SYTTHGTVHV VVNNQIGFTT DPRMARSSPY PTDVARVVNA PIFHVNSDDP EAVMYVCKVA 490 500 510 520 530 540 AEWRNTFHKD VVVDLVCYRR NGHNEMDEPM FTQPLMYKQI RKQKPVLQKY AELLVSQGVV 550 560 570 580 590 600 NQPEYEEEIS KYDKICEEAF TRSKDEKILH IKHWLDSPWP GFFTLDGQPR SMTCPSTGLE 610 620 630 640 650 660 EDVLFHIGKV ASSVPVENFT IHGGLSRILK TRRELVTNRT VDWALAEYMA FGSLLKEGIH 670 680 690 700 710 720 VRLSGQDVER GTFSHRHHVL HDQNVDKRTC IPMNHLWPNQ APYTVCNSSL SEYGVLGFEL 730 740 750 760 770 780 GFAMASPNAL VLWEAQFGDF NNMAQCIIDQ FICPGQAKWV RQNGIVLLLP HGMEGMGPEH 790 800 810 820 830 840 SSARPERFLQ MCNDDPDVLP DLQEENFDIN QLYDCNWIVV NCSTPGNFFH VLRRQILLPF 850 860 870 880 890 900 RKPLIVFTPK SLLRHPEART SFDEMLPGTH FQRVIPENGP AAQDPHKVKR LLFCTGKVYY 910 920 930 940 950 960 DLTRERKARN MEEEVAITRI EQLSPFPFDL LLKEAQKYPN AELAWCQEEH KNQGYYDYVK 970 980 990 1000 1010 PRLRTTIDRA KPVWYAGRDP AAAPATGNKK THLTELQRFL DTAFDLDAFK KFS
	Isoform 3 [UniParc]. Checksum: 7DC3C47068B12D2C		1,038	118,179
	10 20 30 40 50 60 MFHLRTCAAK LRPLTASQTV KTFSQNKPAA IRTFQQIRCY SAPVAAEPFL SGTSSNYVEE 70 80 90 100 110 120 MYCAWLENPK SVHKSWDIFF RNTNAGAPPG TAYQSPLSLS RSSLATMAHA QSLVEAQPNV 130 140 150 160 170 180 DKLVEDHLAV QSLIRAYQIR GHHVAQLDPL GILDADLDSS VPADIISSTD KLDLAVFKER 190 200 210 220 230 240 LRMLTVGGFY GLHESDLDKV FHLPTTTFIG GQEPALPLRE IIRRLEMAYC QHIGVEFMFI 250 260 270 280 290 300 NDLEQCQWIR QKFETPGIMQ FTNEEKRTLL ARLVRSTRFE EFLQRKWSSE KRFGLEGCEV 310 320 330 340 350 360 LIPALKTIID MSSANGVDYV IMGMPHRGRL NVLANVIRKE LEQIFCQFDS KLEAADEGSG 370 380 390 400 410 420 DMKYHLGMYH RRINRVTDRN ITLSLVANPS HLEAADPVVM GKTKAEQFYC GDTEGKKVMS 430 440 450 460 470 480 ILLHGDAAFA GQGIVYETFH LSDLPSYTTH GTVHVVVNNQ IGFTTDPRMA RSSPYPTDVA 490 500 510 520 530 540 RVVNAPIFHV NSDDPEAVMY VCKVAAEWRN TFHKDVVVDL VCYRRNGHNE MDEPMFTQPL 550 560 570 580 590 600 MYKQIRKQKP VLQKYAELLV SQGVVNQPEY EEEISKYDKI CEEAFTRSKD EKILHIKHWL 610 620 630 640 650 660 DSPWPGFFTL DGQPRSMTCP STGLEEDVLF HIGKVASSVP VENFTIHGGL SRILKTRREL 670 680 690 700 710 720 VTNRTVDWAL AEYMAFGSLL KEGIHVRLSG QDVERGTFSH RHHVLHDQNV DKRTCIPMNH 730 740 750 760 770 780 LWPNQAPYTV CNSSLSEYGV LGFELGFAMA SPNALVLWEA QFGDFNNMAQ CIIDQFICPG 790 800 810 820 830 840 QAKWVRQNGI VLLLPHGMEG MGPEHSSARP ERFLQMCNDD PDVLPDLQEE NFDINQLYDC 850 860 870 880 890 900 NWIVVNCSTP GNFFHVLRRQ ILLPFRKPLI VFTPKSLLRH PEARTSFDEM LPGTHFQRVI 910 920 930 940 950 960 PENGPAAQDP HKVKRLLFCT GKVYYDLTRE RKARNMEEEV AITRIEQLSP FPFDLLLKEA 970 980 990 1000 1010 1020 QKYPNAELAW CQEEHKNQGY YDYVKPRLRT TIDRAKPVWY AGRDPAAAPA TGNKKTHLTE 1030 LQRFLDTAFD LDAFKKFS
	Isoform 4 [UniParc]. Checksum: 7023215EEEE9516B		1,034	117,758
	10 20 30 40 50 60 MFHLRTCAAK LRPLTASQTV KTFSQNKPAA IRTFQQIRCY SAPVAAEPFL SGTSSNYVEE 70 80 90 100 110 120 MYCAWLENPK SVHKSWDIFF RNTNAGAPPG TAYQSPLSLS RSSLATMAHA QSLVEAQPNV 130 140 150 160 170 180 DKLVEDHLAV QSLIRAYQVR GHHIAKLDPL GISCVNFDDA PVTVSSNVDL AVFKERLRML 190 200 210 220 230 240 TVGGFYGLHE SDLDKVFHLP TTTFIGGQEP ALPLREIIRR LEMAYCQHIG VEFMFINDLE 250 260 270 280 290 300 QCQWIRQKFE TPGIMQFTNE EKRTLLARLV RSTRFEEFLQ RKWSSEKRFG LEGCEVLIPA 310 320 330 340 350 360 LKTIIDMSSA NGVDYVIMGM PHRGRLNVLA NVIRKELEQI FCQFDSKLEA ADEGSGDMKY 370 380 390 400 410 420 HLGMYHRRIN RVTDRNITLS LVANPSHLEA ADPVVMGKTK AEQFYCGDTE GKKVMSILLH 430 440 450 460 470 480 GDAAFAGQGI VYETFHLSDL PSYTTHGTVH VVVNNQIGFT TDPRMARSSP YPTDVARVVN 490 500 510 520 530 540 APIFHVNSDD PEAVMYVCKV AAEWRNTFHK DVVVDLVCYR RNGHNEMDEP MFTQPLMYKQ 550 560 570 580 590 600 IRKQKPVLQK YAELLVSQGV VNQPEYEEEI SKYDKICEEA FTRSKDEKIL HIKHWLDSPW 610 620 630 640 650 660 PGFFTLDGQP RSMTCPSTGL EEDVLFHIGK VASSVPVENF TIHGGLSRIL KTRRELVTNR 670 680 690 700 710 720 TVDWALAEYM AFGSLLKEGI HVRLSGQDVE RGTFSHRHHV LHDQNVDKRT CIPMNHLWPN 730 740 750 760 770 780 QAPYTVCNSS LSEYGVLGFE LGFAMASPNA LVLWEAQFGD FNNMAQCIID QFICPGQAKW 790 800 810 820 830 840 VRQNGIVLLL PHGMEGMGPE HSSARPERFL QMCNDDPDVL PDLQEENFDI NQLYDCNWIV 850 860 870 880 890 900 VNCSTPGNFF HVLRRQILLP FRKPLIVFTP KSLLRHPEAR TSFDEMLPGT HFQRVIPENG 910 920 930 940 950 960 PAAQDPHKVK RLLFCTGKVY YDLTRERKAR NMEEEVAITR IEQLSPFPFD LLLKEAQKYP 970 980 990 1000 1010 1020 NAELAWCQEE HKNQGYYDYV KPRLRTTIDR AKPVWYAGRD PAAAPATGNK KTHLTELQRF 1030 LDTAFDLDAF KKFS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y. Science 309:1559-1563(2005) [PubMed: 16141072] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). Strain: C57BL/6J. Tissue: Bone marrow.
[2]	"Prediction of the coding sequences of mouse homologues of KIAA gene. The complete nucleotide sequences of mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries." Okazaki N., Kikuno R.F., Ohara R., Inamoto S., Nagase T., Ohara O., Koga H. Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3). Tissue: Brain.
[3]	The mouse genome sequencing consortium Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J.
[4]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2 AND 4). Strain: C57BL/6 and FVB/N. Tissue: Brain, Colon, Mammary tumor and Salivary gland.
[5]	Lubec G., Klug S. Submitted (MAR-2007) to UniProtKB Cited for: PROTEIN SEQUENCE OF 123-135 AND 185-204, MASS SPECTROMETRY. Tissue: Hippocampus.
[6]	Lubec G., Kang S.U. Submitted (APR-2007) to UniProtKB Cited for: PROTEIN SEQUENCE OF 123-135; 311-319; 561-568; 616-633 AND 916-925, MASS SPECTROMETRY. Strain: C57BL/6. Tissue: Brain.
[7]	"A ubiquitous protein is the source of naturally occurring peptides that are recognized by a CD8+ T-cell clone." Udaka K., Tsomides T.J., Walden P., Fukusen N., Eisen H.N. Proc. Natl. Acad. Sci. U.S.A. 90:11272-11276(1993) [PubMed: 8248240] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 829-958 (ISOFORMS 1/2/3/4). Strain: BALB/c.
[8]	"A naturally occurring peptide recognized by alloreactive CD8+ cytotoxic T lymphocytes in association with a class I MHC protein." Udaka K., Tsomides T.J., Eisen H.N. Cell 69:989-998(1992) [PubMed: 1606619] [Abstract] Cited for: PROTEIN SEQUENCE OF 933-939.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AK147289 mRNA. Translation: BAE27824.1. AK150009 mRNA. Translation: BAE29234.1. AK169286 mRNA. Translation: BAE41044.1. AK220536 mRNA. Translation: BAD90530.1. Different initiation. AL607152 Genomic DNA. Translation: CAI24404.1. AL607152 Genomic DNA. Translation: CAI24405.1. AL607152 Genomic DNA. Translation: CAI24406.1. BC025040 mRNA. Translation: AAH25040.1. BC013670 mRNA. Translation: AAH13670.1. BC029143 mRNA. Translation: AAH29143.1. BC031165 mRNA. Translation: AAH31165.1. Different initiation. BC049104 mRNA. Translation: AAH49104.1. BC057354 mRNA. Translation: AAH57354.1. U02971 mRNA. Translation: AAC52130.1.
PIR	A41911. I48884.
RefSeq	NP_035086.2.
UniGene	Mm.276348 Mm.456265 Mm.463333
3D structure databases
ModBase	Search...
PTM databases
PhosphoSite	Q60597.
2-D gel databases
REPRODUCTION-2DPAGE	Q60597.
Genome annotation databases
Ensembl	ENSMUSG00000020456. Mus musculus. [Contig view]
GeneID	18293.
KEGG	mmu:18293.
NMPDR	fig|10090.3.peg.23245.
Organism-specific databases
MGI	MGI:1098267. Ogdh.
Rouge	Search...
Phylogenomic databases
HOVERGEN	Q60597.
Gene expression databases
ArrayExpress	Q60597.
CleanEx	MM_OGDH.
GermOnline	ENSMUSG00000020456. Mus musculus.
Family and domain databases
InterPro	IPR011603. 2oxoglutarate_DHase_E1. IPR001017. DHase_E1. IPR005475. Transketo_Cen_R. [Graphical view]
PANTHER	PTHR23152. 2oxoglutarate_DH_E1. 1 hit.
Pfam	PF00676. E1_dh. 1 hit. PF02779. Transket_pyr. 1 hit. [Graphical view]
PIRSF	PIRSF000157. Oxoglu_dh_E1. 1 hit.
TIGRFAMs	TIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNet	Search...
Other Resources
NextBio	293740.
SOURCE	Search...

Entry information

Entry name

ODO1_MOUSE

Accession

Primary (citable) accession number: Q60597
Secondary accession number(s): Q3UDM7 , Q5DTI4, Q5SVX7, Q5SVX9, Q6PFZ2, Q80Y57, Q8K0K7, Q8K2Z3, Q8R3M2, Q91WP2

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	May 1, 2007
Last modified:	November 25, 2008
This is version 80 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)