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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei140GTPUniRule annotation1
Binding sitei144GTPUniRule annotation1
Binding sitei188GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi22 – 26GTPUniRule annotation5
Nucleotide bindingi109 – 111GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotationImported
Ordered Locus Names:MCA2423Imported
OrganismiMethylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)Imported
Taxonomic identifieri243233 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaMethylococcalesMethylococcaceaeMethylococcus
Proteomesi
  • UP000006821 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi243233.MCA2423.

Structurei

3D structure databases

ProteinModelPortaliQ604W3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 206TubulinInterPro annotationAdd BLAST193
Domaini208 – 326Tubulin_CInterPro annotationAdd BLAST119

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDK. Bacteria.
COG0206. LUCA.
HOGENOMiHOG000049094.
KOiK03531.
OMAiMRAVKGI.
OrthoDBiPOG091H02KK.

Family and domain databases

CDDicd02201. FtsZ_type1. 1 hit.
Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ. 1 hit.
InterProiView protein in InterPro
IPR000158. Cell_div_FtsZ.
IPR020805. Cell_div_FtsZ_CS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR037103. Tubulin/FtsZ_C_sf.
IPR036525. Tubulin/FtsZ_GTPase_sf.
IPR003008. Tubulin_FtsZ_GTPase.
PfamiView protein in Pfam
PF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiView protein in SMART
SM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
PROSITEiView protein in PROSITE
PS01134. FTSZ_1. 1 hit.
PS01135. FTSZ_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q604W3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFELVDSFS PNAVIKVIGV GGGGGNAVNH MVSSQIEGVD FICANTDAQA
60 70 80 90 100
LRNLGARTVI QLGNNLTKGL GAGANPDIGR QAALDDRERI LEVLDGADMV
110 120 130 140 150
FITAGMGGGT GTGAAPVIAE IAKEAGILTV AVVTKPFPFE GRKRRLVADK
160 170 180 190 200
GIAELSQFVD SLITIPNEKL LPVLGKDVSL MAAFAAANDV LLGAVQGIAE
210 220 230 240 250
LITRPGLINV DFADVRTVMS EMGVAMMGTG VGSGPTRARD AAERAIASPL
260 270 280 290 300
LEDISLSGAK GILVNITGGL DLAIGEFDEV GNAVKDYASD EAMVVIGTVI
310 320 330 340 350
DPEMQDEVRV TVVATGLSGQ SQMVSEAPLK LVHKQTGEID YEQMQRPTVL
360 370 380
RKQPKHEPRG EPSKEMDLEY LDIPAFLRRQ AD
Length:382
Mass (Da):40,112
Last modified:November 23, 2004 - v1
Checksum:i1DA0EBF6788DEC2E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017282 Genomic DNA. Translation: AAU91494.1.
RefSeqiWP_010961648.1. NC_002977.6.

Genome annotation databases

EnsemblBacteriaiAAU91494; AAU91494; MCA2423.
KEGGimca:MCA2423.

Similar proteinsi

Entry informationi

Entry nameiQ604W3_METCA
AccessioniPrimary (citable) accession number: Q604W3
Entry historyiIntegrated into UniProtKB/TrEMBL: November 23, 2004
Last sequence update: November 23, 2004
Last modified: October 25, 2017
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported