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Protein

Glycogen synthase 2

Gene

glgA2

Organism
Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Synthesizes alpha-1,4-glucan chains using ADP-glucose.UniRule annotation

Catalytic activityi

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

Pathwayi: glycogen biosynthesis

This protein is involved in the pathway glycogen biosynthesis, which is part of Glycan biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway glycogen biosynthesis and in Glycan biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei12ADP-glucoseUniRule annotation1

GO - Molecular functioni

  • alpha-1,4-glucan synthase activity Source: UniProtKB-EC
  • glycogen (starch) synthase activity Source: InterPro
  • starch synthase activity Source: JCVI

GO - Biological processi

  • glycogen biosynthetic process Source: JCVI

Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processGlycogen biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00164

Protein family/group databases

CAZyiGT5 Glycosyltransferase Family 5

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen synthase 2UniRule annotation (EC:2.4.1.21UniRule annotation)
Alternative name(s):
Starch [bacterial glycogen] synthase 2UniRule annotation
Gene namesi
Name:glgA2UniRule annotation
Ordered Locus Names:MCA2606
OrganismiMethylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)
Taxonomic identifieri243233 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaMethylococcalesMethylococcaceaeMethylococcus
Proteomesi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002302461 – 487Glycogen synthase 2Add BLAST487

Proteomic databases

PRIDEiQ604D9

Interactioni

Protein-protein interaction databases

STRINGi243233.MCA2606

Structurei

3D structure databases

ProteinModelPortaliQ604D9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CXW Bacteria
COG0297 LUCA
HOGENOMiHOG000294940
KOiK00703
OMAiVANDWHS
OrthoDBiPOG091H08HW

Family and domain databases

HAMAPiMF_00484 Glycogen_synth, 1 hit
InterProiView protein in InterPro
IPR001296 Glyco_trans_1
IPR011835 GS/SS
IPR013534 Starch_synth_cat_dom
PfamiView protein in Pfam
PF08323 Glyco_transf_5, 1 hit
PF00534 Glycos_transf_1, 1 hit
TIGRFAMsiTIGR02095 glgA, 1 hit

Sequencei

Sequence statusi: Complete.

Q604D9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHVTPELAPV AKVGGLADVV FGLGRELEIR GNHVEIILPK YDCMRYDQIW
60 70 80 90 100
GLQRTFDDLW VPWYGGAIHC SVYFGFVHGR KCFFIEPHSQ DNFFNRGAVY
110 120 130 140 150
GFHDDIFRFA FFSRAAMEFL WKAGKNPDII HCHDWQTALV PVYLYEIYQP
160 170 180 190 200
MGMRHPRVCF TIHNFKHQGV TGAQVLHASG LDRPEYYFHY DRLRDNHNPH
210 220 230 240 250
AINLMKGGIV YANFVTTVSP RYAMEAKDQG QGFGLEPTLH IHHMKYGGVV
260 270 280 290 300
NGIDYDVWNP EIDPHIPVHF NVDTIEGKYA DKKALRDRLL LADNEKPIVS
310 320 330 340 350
FVGRLDPQKG IELIRHALFY TLGQGGQFVL LGSSPDGAIN GYFWGLKRQF
360 370 380 390 400
NDNPDCHLEI GYNEELAHLV YAGSDVMVVP SRFEPCGLTQ LIAMRYGTIP
410 420 430 440 450
VVREIGGLAD TVIDKDFSHR PLHERNGYVF RDYDERGLES ALGRAIACYY
460 470 480
QYPDHFRELM KNAMRYDYSW NHPGQDYLNI YHYIRDK
Length:487
Mass (Da):56,176
Last modified:April 4, 2006 - v2
Checksum:i5E4DB5E897114933
GO

Sequence cautioni

The sequence AAU91308 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017282 Genomic DNA Translation: AAU91308.1 Different initiation.

Genome annotation databases

EnsemblBacteriaiAAU91308; AAU91308; MCA2606
KEGGimca:MCA2606

Entry informationi

Entry nameiGLGA2_METCA
AccessioniPrimary (citable) accession number: Q604D9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: April 4, 2006
Last modified: May 23, 2018
This is version 80 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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