Q604D9 (GLGA2_METCA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycogen synthase 2
EC=2.4.1.21

Alternative name(s):
Starch [bacterial glycogen] synthase 2

Gene names

Name:	glgA2
Ordered Locus Names:	MCA2606

Organism

Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath) [Complete proteome] [HAMAP]

Taxonomic identifier

243233 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Methylococcales › Methylococcaceae › Methylococcus

Protein attributes

Sequence length	487 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Synthesizes alpha-1,4-glucan chains using ADP-glucose. HAMAP MF_00484
Catalytic activity	ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP MF_00484
Pathway	Glycan biosynthesis; glycogen biosynthesis. HAMAP MF_00484
Sequence similarities	Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Sequence caution	The sequence AAU91308.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	Glycogen biosynthesis
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycogen biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	starch synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 487	487	Glycogen synthase 2 HAMAP MF_00484		PRO_0000230246
Sites
	Binding site	12	1	ADP-glucose By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q604D9 [UniParc]. Last modified April 4, 2006. Version 2. Checksum: 5E4DB5E897114933	FASTA	487	56,176
	10 20 30 40 50 60 MHVTPELAPV AKVGGLADVV FGLGRELEIR GNHVEIILPK YDCMRYDQIW GLQRTFDDLW 70 80 90 100 110 120 VPWYGGAIHC SVYFGFVHGR KCFFIEPHSQ DNFFNRGAVY GFHDDIFRFA FFSRAAMEFL 130 140 150 160 170 180 WKAGKNPDII HCHDWQTALV PVYLYEIYQP MGMRHPRVCF TIHNFKHQGV TGAQVLHASG 190 200 210 220 230 240 LDRPEYYFHY DRLRDNHNPH AINLMKGGIV YANFVTTVSP RYAMEAKDQG QGFGLEPTLH 250 260 270 280 290 300 IHHMKYGGVV NGIDYDVWNP EIDPHIPVHF NVDTIEGKYA DKKALRDRLL LADNEKPIVS 310 320 330 340 350 360 FVGRLDPQKG IELIRHALFY TLGQGGQFVL LGSSPDGAIN GYFWGLKRQF NDNPDCHLEI 370 380 390 400 410 420 GYNEELAHLV YAGSDVMVVP SRFEPCGLTQ LIAMRYGTIP VVREIGGLAD TVIDKDFSHR 430 440 450 460 470 480 PLHERNGYVF RDYDERGLES ALGRAIACYY QYPDHFRELM KNAMRYDYSW NHPGQDYLNI YHYIRDK

References

[1]

"Genomic insights into methanotrophy: the complete genome sequence of Methylococcus capsulatus (Bath)." Ward N.L., Larsen O., Sakwa J., Bruseth L., Khouri H.M., Durkin A.S., Dimitrov G., Jiang L., Scanlan D., Kang K.H., Lewis M.R., Nelson K.E., Methe B.A., Wu M., Heidelberg J.F., Paulsen I.T., Fouts D.E., Ravel J. , Tettelin H., Ren Q., Read T.D., DeBoy R.T., Seshadri R., Salzberg S.L., Jensen H.B., Birkeland N.K., Nelson W.C., Dodson R.J., Grindhaug S.H., Holt I.E., Eidhammer I., Jonasen I., Vanaken S., Utterback T.R., Feldblyum T.V., Fraser C.M., Lillehaug J.R., Eisen J.A. PLoS Biol. 2:1616-1628(2004) [PubMed: 15383840] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33009 / NCIMB 11132 / Bath.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017282 Genomic DNA. Translation: AAU91308.1. Different initiation.
RefSeq	YP_115011.1. NC_002977.6.
3D structure databases
ProteinModelPortal	Q604D9.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3104148.
GenomeReviews	Gene locus MCA2606 in contig AE017282_GR.
KEGG	mca:MCA2606.
NMPDR	fig|243233.4.peg.2536.
PATRIC	22609074. VBIMetCap22254_2637.
TIGR	MCA2606.
Phylogenomic databases
HOGENOM	HBG596384.
OMA	YDCMRYD.
ProtClustDB	PRK00654.
Enzyme and pathway databases
BioCyc	MCAP243233:MCA_2606-MONOMER.
Family and domain databases
HAMAP	MF_00484. Glycogen_synth. [Tree]
InterPro	IPR001296. Glyco_trans_1. IPR011835. Glycogen/starch_synth. IPR013534. Starch_synth_cat_dom. [Graphical view]
KO	K00703.
Pfam	PF08323. Glyco_transf_5. 1 hit. PF00534. Glycos_transf_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR02095. GlgA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLGA2_METCA

Accession

Primary (citable) accession number: Q604D9

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 4, 2006
Last sequence update:	April 4, 2006
Last modified:	January 25, 2012
This is version 45 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program