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Protein

Zinc finger protein 664

Gene

ZNF664

Organism
Cavia porcellus (Guinea pig)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri3 – 2523C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri31 – 5323C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri59 – 8123C2H2-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri87 – 10923C2H2-type 4PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri115 – 13723C2H2-type 5PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri143 – 16523C2H2-type 6PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri171 – 19323C2H2-type 7PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri199 – 22123C2H2-type 8PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri227 – 24923C2H2-type 9PROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 664
Alternative name(s):
Zinc finger protein from organ of Corti
Gene namesi
Name:ZNF664
Synonyms:ZFOC1
OrganismiCavia porcellus (Guinea pig)
Taxonomic identifieri10141 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaHystricognathiCaviidaeCavia
Proteomesi
  • UP000005447 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 261261Zinc finger protein 664PRO_0000296272Add
BLAST

Expressioni

Tissue specificityi

Expressed in the organ of Corti, stria vascularis, auditory nerve and retina. Lower levels in the tongue, cerebellum, small intestine and kidney.1 Publication

Interactioni

Protein-protein interaction databases

STRINGi10141.ENSCPOP00000013001.

Structurei

3D structure databases

ProteinModelPortaliQ60493.
SMRiQ60493. Positions 59-251.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 9 C2H2-type zinc fingers.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri3 – 2523C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri31 – 5323C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri59 – 8123C2H2-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri87 – 10923C2H2-type 4PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri115 – 13723C2H2-type 5PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri143 – 16523C2H2-type 6PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri171 – 19323C2H2-type 7PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri199 – 22123C2H2-type 8PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri227 – 24923C2H2-type 9PROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
HOGENOMiHOG000234617.
HOVERGENiHBG018163.
InParanoidiQ60493.

Family and domain databases

Gene3Di3.30.160.60. 9 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF00096. zf-C2H2. 4 hits.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 9 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 9 hits.
PS50157. ZINC_FINGER_C2H2_2. 9 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q60493-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIYKCPMCRE FFSERADLFM HQKVHTAEKP HKCDKCDKGF FHISELHIHW
60 70 80 90 100
RDHTGEKVYK CDDCGKDFST TTKLNRHKKI HTVEKPYKCY ECGKAFNWSP
110 120 130 140 150
HLQIHMRVHT GEKPYVCSEC GRGFSNSSNL CMHQRVHTGE KPFKCEECGK
160 170 180 190 200
AFRHTSSLCM HQRVHTGEKP YKCYECGKAF SQSSSLCIHQ RVHTGEKPYR
210 220 230 240 250
CCGCGKAFSQ SSSLCIHQRV HTGEKPFKCD ECGKAFSQST SLCIHQRVHT
260
KERNHLKISV I
Length:261
Mass (Da):30,280
Last modified:November 1, 1996 - v1
Checksum:iACE5BD4A96FE9DEF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L26335 mRNA. Translation: AAC42091.1.
PIRiS70006.
RefSeqiNP_001166361.1. NM_001172890.1.

Genome annotation databases

GeneIDi100379578.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L26335 mRNA. Translation: AAC42091.1.
PIRiS70006.
RefSeqiNP_001166361.1. NM_001172890.1.

3D structure databases

ProteinModelPortaliQ60493.
SMRiQ60493. Positions 59-251.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10141.ENSCPOP00000013001.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100379578.

Organism-specific databases

CTDi144348.

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
HOGENOMiHOG000234617.
HOVERGENiHBG018163.
InParanoidiQ60493.

Family and domain databases

Gene3Di3.30.160.60. 9 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF00096. zf-C2H2. 4 hits.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 9 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 9 hits.
PS50157. ZINC_FINGER_C2H2_2. 9 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiZN664_CAVPO
AccessioniPrimary (citable) accession number: Q60493
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: November 1, 1996
Last modified: May 11, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.