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Q603U2 (ATPA2_METCA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
ATP synthase subunit alpha 2
EC=3.6.3.14
Alternative name(s):
ATP synthase F1 sector subunit alpha 2
F-ATPase subunit alpha 2
Gene names
Name:atpA2
Synonyms:atpA-2
Ordered Locus Names:MCA2707
OrganismMethylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath) [Complete proteome] [HAMAP]
Taxonomic identifier243233 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Methylococcales › Methylococcaceae › Methylococcus

Protein attributes

Sequence length503 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit By similarity. HAMAP MF_01346

Catalytic activity

ATP + H2O + H+(In) = ADP + phosphate + H+(Out). HAMAP MF_01346

Subunit structure

F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a1, b2 and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF1 is attached to CF0 by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains By similarity.

Subcellular location

Cell inner membrane; Peripheral membrane protein By similarity HAMAP MF_01346.

Sequence similarities

Belongs to the ATPase alpha/beta chains family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 503503ATP synthase subunit alpha 2 HAMAP MF_01346
PRO_0000238286

Sites

Site3711Required for activity By similarity

Sequences

Sequence LengthMass (Da)Tools
Q603U2 [UniParc].

Last modified November 23, 2004. Version 1.
Checksum: 584C3ABB8F5C2414

FASTA50354,947
        10         20         30         40         50         60 
MNAGSENSTP RISEPASPLA QAVHIGDYRP RLRIGEYGTV ASVGDGIAWV TGLPSAAMDD 

        70         80         90        100        110        120 
VLMFEDGSWA VVFALTKKRI GAVLLHQSEN LTAGTPARLA GRTLDVPVGE TLLGRVIDPI 

       130        140        150        160        170        180 
GNPLDGGRPL ETRNRRPLDS PSPPIIARDF VQQPLYTGTR LVDTLVPIGK GQRQLIIGDE 

       190        200        210        220        230        240 
GTGRSSLAID AVLNQKGREV RCVYVLIGQK RSTVVGTIEL LRNYGALAYT TVVVGEAGSL 

       250        260        270        280        290        300 
PGLKYLAPFA GCAIAEDWMA RGHDTLVVYD DLSTHAQTYR ELSLLLRRPP GREAYPGDIF 

       310        320        330        340        350        360 
YLHARLLERA TALNPANGGG SMTALPIVET RLGEIEAYIP TNLISITDGQ IYLDSDLFAA 

       370        380        390        400        410        420 
GFKPAIDVTR SVSRIGGKAQ HPRIKEEAGR MKLDYLQFLE LEIFTRFGAR LESGMEARIR 

       430        440        450        460        470        480 
RGRLLREILR QERLQPLPPE FQLAWMTAYN EGLLDAMPPG SVQHALNELN SALRNGSPPL 

       490        500 
EASRTDWLTW LRQNLPEPAR GEA

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE017282 Genomic DNA. Translation: AAU91234.1.
RefSeqYP_115108.1. NC_002977.6.

3D structure databases

ProteinModelPortalQ603U2.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3104545.
GenomeReviewsGene locus MCA2707 in contig AE017282_GR.
KEGGmca:MCA2707.
NMPDRfig|243233.4.peg.2633.
PATRIC22609278. VBIMetCap22254_2739.
TIGRMCA2707.

Phylogenomic databases

HOGENOMHBG565875.
OMAHAQTYRE.
ProtClustDBPRK13343.

Enzyme and pathway databases

BioCycMCAP243233:MCA_2707-MONOMER.

Family and domain databases

HAMAPMF_01346. ATP_synth_alpha_bact.
[Tree]
InterProIPR020003. ATPase_a/bsu_AS.
IPR005294. ATPase_F1-cplx_asu.
IPR018118. ATPase_F1/A1-cplx_a/bsu_N.
IPR023366. ATPase_F1/A1-cplx_a_su_N.
IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C.
IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
[Graphical view]
Gene3DG3DSA:2.40.30.20. G3DSA:2.40.30.20. 1 hit.
KOK02111.
PANTHERPTHR15184:SF3. ATPase_F1_a. 1 hit.
PfamPF00006. ATP-synt_ab. 1 hit.
PF00306. ATP-synt_ab_C. 1 hit.
[Graphical view]
SUPFAMSSF47917. ATPase_a/b_C. 1 hit.
SSF50615. ATPase_a/b_N. 1 hit.
TIGRFAMsTIGR00962. AtpA. 1 hit.
PROSITEPS00152. ATPASE_ALPHA_BETA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameATPA2_METCA
AccessionPrimary (citable) accession number: Q603U2
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: November 23, 2004
Last modified: January 25, 2012
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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