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Q60387 (MCRZ_METJA) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 88. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Methyl-coenzyme M reductase II subunit gamma

Short name=MCR II gamma
EC=2.8.4.1
Alternative name(s):
Coenzyme-B sulfoethylthiotransferase gamma
Gene names
Name:mrtG
Synonyms:mtrG
Ordered Locus Names:MJ0082
OrganismMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) [Reference proteome] [HAMAP]
Taxonomic identifier243232 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus

Protein attributes

Sequence length266 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and a heterodisulfide By similarity.

Catalytic activity

Methyl-CoM + CoB = CoM-S-S-CoB + methane.

Cofactor

Binds 2 coenzyme F430 noncovalently per hexamer. Coenzyme F430 is a yellow nickel porphinoid By similarity.

Pathway

One-carbon metabolism; methyl-coenzyme M reduction; methane from methyl-coenzyme M: step 1/1.

Subunit structure

Hexamer of two alpha, two beta, and two gamma chains By similarity.

Ontologies

Keywords
   Biological processMethanogenesis
   Molecular functionTransferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processmethanogenesis

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functioncoenzyme-B sulfoethylthiotransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 266266Methyl-coenzyme M reductase II subunit gamma
PRO_0000147477

Sequences

Sequence LengthMass (Da)Tools
Q60387 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: 51E7B3C7F984157A

FASTA26630,764
        10         20         30         40         50         60 
MAYKPQFYPG NTLIAENRRK HMNPEVELKK LRDIPDDEIV KILGHRNPGE SYKTVHPPLE 

        70         80         90        100        110        120 
EMDFEEDPIK DIVEPIQGAK EGVRVRYIQF ADSMYNAPAQ PYDRARTYMW RFRGIDTGTL 

       130        140        150        160        170        180 
SGRQVIEMRE LDLEKISKNF LIDTEFFDPA TCGIRGATVH GHSLRLDENG LMFDGLQRYI 

       190        200        210        220        230        240 
YDEKTGHVLY VKDQVGRPLD EPVDVGEPLP HDYLAKITTI YRKDNIGMRE DKEALEVVQI 

       250        260 
IHEARTKGGF GLEVFKKDLK KRLGEE 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L77117 Genomic DNA. Translation: AAB98062.1.
PIRB64310.
RefSeqNP_247046.1. NC_000909.1.

3D structure databases

ProteinModelPortalQ60387.
SMRQ60387. Positions 6-252.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243232.MJ0082.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB98062; AAB98062; MJ_0082.
GeneID1450921.
KEGGmja:MJ_0082.

Phylogenomic databases

eggNOGCOG4057.
KOK00402.
OMAGHRNPGE.
PhylomeDBQ60387.

Enzyme and pathway databases

UniPathwayUPA00646; UER00699.

Family and domain databases

Gene3D3.90.320.20. 1 hit.
InterProIPR009024. Me_CoM_Rdtase_Fd-like_fold.
IPR003178. Me_CoM_Rdtase_gsu.
[Graphical view]
PfamPF02240. MCR_gamma. 1 hit.
[Graphical view]
PIRSFPIRSF000264. Meth_CoM_rd_gama. 1 hit.
ProDomPD005845. Me_CoM_Rdtase_gsu. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF55088. SSF55088. 1 hit.
TIGRFAMsTIGR03259. met_CoM_red_gam. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMCRZ_METJA
AccessionPrimary (citable) accession number: Q60387
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: July 9, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

Methanococcus jannaschii

Methanococcus jannaschii: entries and gene names