Reviewed,
UniProtKB/Swiss-Prot Q60387 (MCRZ_METJA)
Last modified
November 3, 2009.
Version 58.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Methyl-coenzyme M reductase II subunit gamma Short name=MCR II gamma EC=2.8.4.1 Alternative name(s): Coenzyme-B sulfoethylthiotransferase gamma | ||||||
| Gene names |
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| Organism | Methanocaldococcus jannaschii (Methanococcus jannaschii) [Complete proteome] [HAMAP] | ||||||
| Taxonomic identifier | 2190 [NCBI] | ||||||
| Taxonomic lineage | Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus |
Protein attributes
| Sequence length | 266 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and an heterodisulfide By similarity. |
| Catalytic activity | 2-(methylthio)ethanesulfonate (methyl-CoM) + N-(7-mercaptoheptanoyl)threonine 3-O-phosphate (coenzyme B) = CoM-S-S-CoB + methane. |
| Cofactor | Binds 2 coenzyme F430 noncovalently per hexamer. Coenzyme F430 is a yellow nickel porphinoid By similarity. |
| Pathway | One-carbon metabolism; methyl-coenzyme M reduction; methane from methyl-coenzyme M: step 1/1. |
| Subunit structure | Hexamer of two alpha, two beta, and two gamma chains By similarity. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Methanogenesis |
| Molecular function | Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | methanogenesis Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | coenzyme-B sulfoethylthiotransferase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 266 | 266 | Methyl-coenzyme M reductase II subunit gamma | PRO_0000147477 | |||
Sequences
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References
| [1] | "Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii." Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G., Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R., Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R., Kirkness E.F., Weinstock K.G. Venter J.C.Science 273:1058-1073(1996) [PubMed: 8688087] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440. |
Cross-references
Sequence databases | |
|---|---|
| L77117 Genomic DNA. Translation: AAB98062.1. | |
| PIR | B64310. |
| RefSeq | NP_247046.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1E6V based on UniProtKB Q49604. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 1450921. |
| GenomeReviews | Gene locus MJ0082 in contig L77117_GR. |
| KEGG | mja:MJ0082. |
| NMPDR | fig|243232.1.peg.83. |
| TIGR | MJ0082. |
Phylogenomic databases | |
| HOGENOM | Q60387. |
| OMA | VIEMREL. |
Enzyme and pathway databases | |
| BioCyc | MJAN243232:MJ_0082-MON. |
| BRENDA | 2.8.4.1. 256362. |
Family and domain databases | |
| InterPro | IPR003178. Me_CoM_Rdtase_gsu. [Graphical view] |
| Gene3D | G3DSA:3.90.320.20. MCR_gamma. 1 hit. |
| Pfam | PF02240. MCR_gamma. 1 hit. [Graphical view] |
| PIRSF | PIRSF000264. Meth_CoM_rd_gama. 1 hit. |
| ProDom | PD005845. MCR_gamma. 1 hit. [Graphical view] [Entries sharing at least one domain] |
| TIGRFAMs | TIGR03259. met_CoM_red_gam. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | MCRZ_METJA | ||||||||
| Accession | Primary (citable) accession number: Q60387 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| Methanococcus jannaschii Methanococcus jannaschii: entries and gene names |
| PATHWAY comments Index of metabolic and biosynthesis pathways |

Clusters with


