Q60374 (RELE1_METJA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative toxin RelE1

Gene names

Name:	relE1
Ordered Locus Names:	MJ0071

Organism

Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)

Taxonomic identifier

243232 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus

Protein attributes

Sequence length	90 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Toxic component of a toxin-antitoxin (TA) module. Its cognate antitoxin is RelB1 Potential. Ref.2
Sequence similarities	Belongs to the RelE toxin family.

Ontologies

Keywords
Molecular function	Toxin
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 90	90	Putative toxin RelE1		PRO_0000106679

Sequences

	Sequence		Length	Mass (Da)
	Q60374 [UniParc]. Last modified November 1, 1997. Version 1. Checksum: 78902F645671F70A	FASTA	90	10,851
	10 20 30 40 50 60 MKFNVEIHKR VLKDLKDLPP SNLKKFKELI ETLKTNPIPK EKFDIKRLKG SDEVYRVRIG 70 80 90 KFRVQYVVLW DDRIIIIRKI SRREGAYKNP

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii." Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G., Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R., Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R., Kirkness E.F., Weinstock K.G. , Merrick J.M., Glodek A., Scott J.L., Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R., Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D., Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P., Fraser C.M., Smith H.O., Woese C.R., Venter J.C. Science 273:1058-1073(1996) [PubMed: 8688087] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.
[2]	"Toxin-antitoxin loci are highly abundant in free-living but lost from host-associated prokaryotes." Pandey D.P., Gerdes K. Nucleic Acids Res. 33:966-976(2005) [PubMed: 15718296] [Abstract] Cited for: POSSIBLE FUNCTION. Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L77117 Genomic DNA. Translation: AAB98049.1.
PIR	G64308.
RefSeq	NP_247035.1. NC_000909.1.
3D structure databases
ProteinModelPortal	Q60374.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1450910.
GenomeReviews	Gene locus MJ0071 in contig L77117_GR.
KEGG	mja:MJ_0071.
NMPDR	fig|243232.1.peg.72.
TIGR	MJ0071.
Phylogenomic databases
HOGENOM	HBG705334.
OMA	RREGAYK.
ProtClustDB	CLSK542025.
Enzyme and pathway databases
BioCyc	MJAN243232:MJ_0071-MONOMER.
Family and domain databases
InterPro	IPR007712. Plasmid_stabil. [Graphical view]
Pfam	PF05016. Plasmid_stabil. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RELE1_METJA

Accession

Primary (citable) accession number: Q60374

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	October 19, 2011
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program