Q60356 (Y033_METJA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized FAD-dependent oxidoreductase MJ0033

Gene names

Ordered Locus Names:

MJ0033

Organism

Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)

Taxonomic identifier

243232 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus

Protein attributes

Sequence length	539 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	FAD By similarity.
Sequence similarities	Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

Ontologies

Keywords
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	electron carrier activity Inferred from electronic annotation. Source: InterPro oxidoreductase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 539	539	Uncharacterized FAD-dependent oxidoreductase MJ0033		PRO_0000158670
Regions
	Nucleotide binding	6 – 20	15	FAD Potential
Sites
	Active site	227	1	By similarity
	Active site	243	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q60356 [UniParc]. Last modified November 1, 1997. Version 1. Checksum: 89FF7AE3D6268795	FASTA	539	60,398
	10 20 30 40 50 60 MKTDILIIGG GGAAARAAIE CRDKNVIIAV KGLFGKSGCT VMAEGGYNAV FNPKDSFKKH 70 80 90 100 110 120 FYDTVKGGGF INNPKLVEIL VKNAPKELLN LERFGALFDR TEDGFIAQRP FGGQSFNRTC 130 140 150 160 170 180 YCGDRTGHEI MRGLMEYISK FERIKILEEV MAIKLIVKDN RCYGAIFLDL KTGNIFPIFA 190 200 210 220 230 240 KATILATGGA GQLYPITSNP IQKTGDGFAI AYNEGAELID MEMVQFHPTG MVGTGILVTE 250 260 270 280 290 300 AVRGEGGILY NKYKERFMVR YDKERMELST RDVVARAIYK EIQEGRGVNG GVYLDVSHLP 310 320 330 340 350 360 NEVIEKKLET MLKQFLRVGI DIRKEPMIVS PTAHHFMGGL KINERCETNI IGLFACGEVT 370 380 390 400 410 420 GGVHGANRLG GNALADTQVF GAIAGKSAKE FVENHDFNNI DAEEDVAKIL EEINSLKGDL 430 440 450 460 470 480 NVYNLIEDLR KVMWDYVSII RNEDGLKKAL EKIDEIERNI DNVKVNGIID LQNYFELKNM 490 500 510 520 530 VVVAKLVTKS ALYRKESRGA HYREDFPETK EEWRGNIIIK GKKMWFEKLD YSVFQNFLE

References

[1]

"Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii." Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G., Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R., Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R., Kirkness E.F., Weinstock K.G. , Merrick J.M., Glodek A., Scott J.L., Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R., Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D., Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P., Fraser C.M., Smith H.O., Woese C.R., Venter J.C. Science 273:1058-1073(1996) [PubMed: 8688087] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L77117 Genomic DNA. Translation: AAB98014.1.
PIR	A64304.
RefSeq	NP_246996.1. NC_000909.1.
3D structure databases
ProteinModelPortal	Q60356.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1450871.
GenomeReviews	Gene locus MJ0033 in contig L77117_GR.
KEGG	mja:MJ_0033.
NMPDR	fig|243232.1.peg.33.
TIGR	MJ0033.
Phylogenomic databases
HOGENOM	HBG293998.
OMA	ENPYTLH.
ProtClustDB	PRK06263.
Enzyme and pathway databases
BioCyc	MJAN243232:MJ_0033-MONOMER.
Family and domain databases
InterPro	IPR003953. FAD_bind2_N. IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR015939. Fum_Rdtase/Succ_DH_flav-like_C. IPR004112. Fum_Rdtase/Succ_DH_flav_C. [Graphical view]
Gene3D	G3DSA:1.20.58.100. Fum_Rdtase/Succ_DH_flav-like_C. 1 hit.
KO	K00239.
Pfam	PF00890. FAD_binding_2. 1 hit. PF02910. Succ_DH_flav_C. 1 hit. [Graphical view]
PRINTS	PR00368. FADPNR.
SUPFAM	SSF46977. Succ_DH_flav_C. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Y033_METJA

Accession

Primary (citable) accession number: Q60356

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	November 16, 2011
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program