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Reviewed, UniProtKB/Swiss-Prot Q60340 (FRHG_METJA)

Last modified November 25, 2008. Version 56. Feed History...

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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Coenzyme F420 hydrogenase subunit gamma
    EC=1.12.98.1
Alternative name(s):
    8-hydroxy-5-deazaflavin-reducing hydrogenase subunit gamma
      Short name=FRH
Gene names
Name: frhG
Ordered Locus Names: MJ0031
OrganismMethanocaldococcus jannaschii (Methanococcus jannaschii) [Complete proteome] [HAMAP]
Taxonomic identifier2190 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus

Protein attributes

Sequence length230 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Reduces the physiological low-potential two-electron acceptor coenzyme F420, and the artificial one-electron acceptor methylviologen By similarity.

Catalytic activity

H(2) + coenzyme F420 = reduced coenzyme F420.

Subunit structure

Heterocomplex of the form (alpha(1)beta(1)gamma(1))(8) By similarity.

Sequence similarities

Belongs to the frhG family.

Contains 2 4Fe-4S ferredoxin-type domains.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 230230Coenzyme F420 hydrogenase subunit gamma
PRO_0000159232

Regions

Domain169 – 197294Fe-4S ferredoxin-type 1
Domain198 – 228314Fe-4S ferredoxin-type 2

Sites

Metal binding1781Iron-sulfur 1 (4Fe-4S) By similarity
Metal binding1811Iron-sulfur 1 (4Fe-4S) By similarity
Metal binding1841Iron-sulfur 1 (4Fe-4S) By similarity
Metal binding1881Iron-sulfur 2 (4Fe-4S) By similarity
Metal binding2071Iron-sulfur 2 (4Fe-4S) By similarity
Metal binding2101Iron-sulfur 2 (4Fe-4S) By similarity
Metal binding2131Iron-sulfur 2 (4Fe-4S) By similarity
Metal binding2171Iron-sulfur 1 (4Fe-4S) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q60340-1 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: 6C9936D3A20ED356

FASTA23024,534
        10         20         30         40         50         60 
MIKVVKVAHV QLCSCCGCLV SLADTYEKLL DVLNSIELVY CQTLADAREI PECDIALVEG 

        70         80         90        100        110        120 
SVCLDDHHSL EVAQEVRKKA KIVVALGACA ATGGVTRYCK GNQLSKPVHS SFSPLTEVIK 

       130        140        150        160        170        180 
VDLAIPGCPP SPEAIVGVIT AALNGDMEYL QPYAELAEKG SEACGCDVIY KVVNKSLCMG 

       190        200        210        220        230 
CGTCAAACPT RAIEMLDGRP NVLKELCIKC GACSVQCPRI RFPELIEKIE 

« Hide

Cross-references

Sequence databases

L77117 Genomic DNA. Translation: AAB98010.1.
PIRG64303.
RefSeqNP_246994.1.

3D structure databases

HSSPHSSP built from PDB template 2FDN based on UniProtKB P00198.
ModBaseSearch...

Genome annotation databases

GeneID1450869.
GenomeReviewsGene locus MJ0031 in contig L77117_GR.
KEGGmja:MJ0031.
NMPDRfig|243232.1.peg.31.
TIGRMJ0031.

Phylogenomic databases

HOGENOMQ60340.

Enzyme and pathway databases

BioCycMJAN243232:MJ_0031-MON.

Family and domain databases

InterProIPR001450. 4Fe4S_Fe_S_bd.
IPR017681. Coenz_F4210_hydrogenase_gsu.
IPR014406. NiFe_hyd_3_ssu/Q_oxred_NuoB.
IPR001821. NiFe_hyd_ssu.
IPR006137. OxRdtase_q6.
[Graphical view]
PANTHERPTHR11995. NiFe_hyd_3_ssu/Q_oxred_NuoB. 1 hit.
PfamPF00037. Fer4. 2 hits.
PF01058. Oxidored_q6. 1 hit.
[Graphical view]
PRINTSPR00353. 4FE4SFRDOXIN.
PR00614. NIHGNASESMLL.
PROSITEPS00198. 4FE4S_FER_1. 2 hits.
PS51379. 4FE4S_FER_2. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameFRHG_METJA
AccessionPrimary (citable) accession number: Q60340
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: November 25, 2008
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

Methanococcus jannaschii

Methanococcus jannaschii: entries and gene names

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents