SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q60340

- FRHG_METJA

UniProt

Q60340 - FRHG_METJA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Coenzyme F420 hydrogenase subunit gamma
Gene
frhG, MJ0031
Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Reduces the physiological low-potential two-electron acceptor coenzyme F420, and the artificial one-electron acceptor methylviologen By similarity.

Catalytic activityi

H2 + oxidized coenzyme F420 = reduced coenzyme F420.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi178 – 1781Iron-sulfur 1 (4Fe-4S) By similarity
Metal bindingi181 – 1811Iron-sulfur 1 (4Fe-4S) By similarity
Metal bindingi184 – 1841Iron-sulfur 1 (4Fe-4S) By similarity
Metal bindingi188 – 1881Iron-sulfur 2 (4Fe-4S) By similarity
Metal bindingi207 – 2071Iron-sulfur 2 (4Fe-4S) By similarity
Metal bindingi210 – 2101Iron-sulfur 2 (4Fe-4S) By similarity
Metal bindingi213 – 2131Iron-sulfur 2 (4Fe-4S) By similarity
Metal bindingi217 – 2171Iron-sulfur 1 (4Fe-4S) By similarity

GO - Molecular functioni

  1. 4 iron, 4 sulfur cluster binding Source: UniProtKB-KW
  2. coenzyme F420 hydrogenase activity Source: UniProtKB-EC
  3. ferredoxin hydrogenase activity Source: InterPro
  4. flavin adenine dinucleotide binding Source: InterPro
  5. nickel cation binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Electron transport, Transport

Keywords - Ligandi

4Fe-4S, Iron, Iron-sulfur, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Coenzyme F420 hydrogenase subunit gamma (EC:1.12.98.1)
Alternative name(s):
8-hydroxy-5-deazaflavin-reducing hydrogenase subunit gamma
Short name:
FRH
Gene namesi
Name:frhG
Ordered Locus Names:MJ0031
OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifieri243232 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
ProteomesiUP000000805: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. ferredoxin hydrogenase complex Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 230230Coenzyme F420 hydrogenase subunit gamma
PRO_0000159232Add
BLAST

Interactioni

Subunit structurei

Heterocomplex of the form (alpha1beta1gamma1)8 By similarity.

Protein-protein interaction databases

STRINGi243232.MJ0031.

Structurei

3D structure databases

ProteinModelPortaliQ60340.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini169 – 197294Fe-4S ferredoxin-type 1
Add
BLAST
Domaini198 – 228314Fe-4S ferredoxin-type 2
Add
BLAST

Sequence similaritiesi

Belongs to the FrhG family.

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiCOG1941.
KOiK00443.
OMAiCPPSPEI.
PhylomeDBiQ60340.

Family and domain databases

Gene3Di3.40.50.700. 1 hit.
InterProiIPR001450. 4Fe4S-bd_dom.
IPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
IPR017681. Coenz_F420_hydrogenase_gsu.
IPR006137. NADH_UbQ_OxRdtase-like_20kDa.
IPR001821. NiFe_hydrogenase_ssu.
[Graphical view]
PfamiPF00037. Fer4. 1 hit.
PF01058. Oxidored_q6. 1 hit.
[Graphical view]
PRINTSiPR00614. NIHGNASESMLL.
TIGRFAMsiTIGR03294. FrhG. 1 hit.
PROSITEiPS00198. 4FE4S_FER_1. 2 hits.
PS51379. 4FE4S_FER_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q60340-1 [UniParc]FASTAAdd to Basket

« Hide

MIKVVKVAHV QLCSCCGCLV SLADTYEKLL DVLNSIELVY CQTLADAREI    50
PECDIALVEG SVCLDDHHSL EVAQEVRKKA KIVVALGACA ATGGVTRYCK 100
GNQLSKPVHS SFSPLTEVIK VDLAIPGCPP SPEAIVGVIT AALNGDMEYL 150
QPYAELAEKG SEACGCDVIY KVVNKSLCMG CGTCAAACPT RAIEMLDGRP 200
NVLKELCIKC GACSVQCPRI RFPELIEKIE 230
Length:230
Mass (Da):24,534
Last modified:November 1, 1997 - v1
Checksum:i6C9936D3A20ED356
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L77117 Genomic DNA. Translation: AAB98010.1.
PIRiG64303.
RefSeqiNP_246994.1. NC_000909.1.

Genome annotation databases

EnsemblBacteriaiAAB98010; AAB98010; MJ_0031.
GeneIDi1450869.
KEGGimja:MJ_0031.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L77117 Genomic DNA. Translation: AAB98010.1 .
PIRi G64303.
RefSeqi NP_246994.1. NC_000909.1.

3D structure databases

ProteinModelPortali Q60340.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243232.MJ0031.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAB98010 ; AAB98010 ; MJ_0031 .
GeneIDi 1450869.
KEGGi mja:MJ_0031.

Phylogenomic databases

eggNOGi COG1941.
KOi K00443.
OMAi CPPSPEI.
PhylomeDBi Q60340.

Family and domain databases

Gene3Di 3.40.50.700. 1 hit.
InterProi IPR001450. 4Fe4S-bd_dom.
IPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
IPR017681. Coenz_F420_hydrogenase_gsu.
IPR006137. NADH_UbQ_OxRdtase-like_20kDa.
IPR001821. NiFe_hydrogenase_ssu.
[Graphical view ]
Pfami PF00037. Fer4. 1 hit.
PF01058. Oxidored_q6. 1 hit.
[Graphical view ]
PRINTSi PR00614. NIHGNASESMLL.
TIGRFAMsi TIGR03294. FrhG. 1 hit.
PROSITEi PS00198. 4FE4S_FER_1. 2 hits.
PS51379. 4FE4S_FER_2. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

Entry informationi

Entry nameiFRHG_METJA
AccessioniPrimary (citable) accession number: Q60340
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: July 9, 2014
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Methanococcus jannaschii
    Methanococcus jannaschii: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi