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Q60340 (FRHG_METJA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 91. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Coenzyme F420 hydrogenase subunit gamma

EC=1.12.98.1
Alternative name(s):
8-hydroxy-5-deazaflavin-reducing hydrogenase subunit gamma
Short name=FRH
Gene names
Name:frhG
Ordered Locus Names:MJ0031
OrganismMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) [Reference proteome] [HAMAP]
Taxonomic identifier243232 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus

Protein attributes

Sequence length230 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Reduces the physiological low-potential two-electron acceptor coenzyme F420, and the artificial one-electron acceptor methylviologen By similarity.

Catalytic activity

H2 + oxidized coenzyme F420 = reduced coenzyme F420.

Subunit structure

Heterocomplex of the form (alpha1beta1gamma1)8 By similarity.

Sequence similarities

Belongs to the FrhG family.

Contains 2 4Fe-4S ferredoxin-type domains.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 230230Coenzyme F420 hydrogenase subunit gamma
PRO_0000159232

Regions

Domain169 – 197294Fe-4S ferredoxin-type 1
Domain198 – 228314Fe-4S ferredoxin-type 2

Sites

Metal binding1781Iron-sulfur 1 (4Fe-4S) By similarity
Metal binding1811Iron-sulfur 1 (4Fe-4S) By similarity
Metal binding1841Iron-sulfur 1 (4Fe-4S) By similarity
Metal binding1881Iron-sulfur 2 (4Fe-4S) By similarity
Metal binding2071Iron-sulfur 2 (4Fe-4S) By similarity
Metal binding2101Iron-sulfur 2 (4Fe-4S) By similarity
Metal binding2131Iron-sulfur 2 (4Fe-4S) By similarity
Metal binding2171Iron-sulfur 1 (4Fe-4S) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q60340 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: 6C9936D3A20ED356

FASTA23024,534
        10         20         30         40         50         60 
MIKVVKVAHV QLCSCCGCLV SLADTYEKLL DVLNSIELVY CQTLADAREI PECDIALVEG 

        70         80         90        100        110        120 
SVCLDDHHSL EVAQEVRKKA KIVVALGACA ATGGVTRYCK GNQLSKPVHS SFSPLTEVIK 

       130        140        150        160        170        180 
VDLAIPGCPP SPEAIVGVIT AALNGDMEYL QPYAELAEKG SEACGCDVIY KVVNKSLCMG 

       190        200        210        220        230 
CGTCAAACPT RAIEMLDGRP NVLKELCIKC GACSVQCPRI RFPELIEKIE 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L77117 Genomic DNA. Translation: AAB98010.1.
PIRG64303.
RefSeqNP_246994.1. NC_000909.1.

3D structure databases

ProteinModelPortalQ60340.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243232.MJ0031.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB98010; AAB98010; MJ_0031.
GeneID1450869.
KEGGmja:MJ_0031.

Phylogenomic databases

eggNOGCOG1941.
KOK00443.
OMACPPSPEI.
ProtClustDBCLSK876042.

Family and domain databases

Gene3D3.40.50.700. 1 hit.
InterProIPR001450. 4Fe4S-bd_dom.
IPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
IPR017681. Coenz_F420_hydrogenase_gsu.
IPR006137. NADH_UbQ_OxRdtase-like_20kDa.
IPR001821. NiFe_hydrogenase_ssu.
[Graphical view]
PfamPF00037. Fer4. 1 hit.
PF01058. Oxidored_q6. 1 hit.
[Graphical view]
PRINTSPR00614. NIHGNASESMLL.
TIGRFAMsTIGR03294. FrhG. 1 hit.
PROSITEPS00198. 4FE4S_FER_1. 2 hits.
PS51379. 4FE4S_FER_2. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameFRHG_METJA
AccessionPrimary (citable) accession number: Q60340
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: February 19, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Methanococcus jannaschii

Methanococcus jannaschii: entries and gene names