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Q60337 (THIL_METJA) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable thiamine-monophosphate kinase
Short name=Thiamine-phosphate kinase
EC=2.7.4.16
Gene names
Name:thiL
Ordered Locus Names:MJ0028
OrganismMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifier243232 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus

Protein attributes

Sequence length319 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thiamine phosphate = ADP + thiamine diphosphate.

Pathway

Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine diphosphate from thiamine phosphate: step 1/1.

Sequence similarities

Belongs to the thiamine-monophosphate kinase family.

Ontologies

Keywords
   Biological processThiamine biosynthesis
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processthiamine biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

thiamine-phosphate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 319319Probable thiamine-monophosphate kinase
PRO_0000096201

Sequences

Sequence LengthMass (Da)Tools
Q60337 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: 92607D5AD59A723F

FASTA31936,160
        10         20         30         40         50         60 
MDEMKVIEII KKTLKFSNEN IVKGIDDDCA IIKIDENFYL VATTDMMVKK AHIPSILSPY 

        70         80         90        100        110        120 
EIGGRILTAN VSDIASMGAK PLAFLVSISL SKEEANEKFI KELYSGLDDF SKLYDCPVVG 

       130        140        150        160        170        180 
GDTNRGDELI LSGTAFGITD NPIYRRGKVG DDICVTNDLG RVYCALTLYY MLKENKISYK 

       190        200        210        220        230        240 
EFERLCQKYP KIIEKLRKPI ARIKEGLLMN KLINGCCDIS DGLGKEITYF KNFEIYSDRI 

       250        260        270        280        290        300 
FKLIPEDVIE FCDAFNLNPI KVALNSGEEF ELLFTTSKFN KVKDSLKGYS KIYKIGKIIE 

       310 
DGQFIDGEEF YGGGYIHKW

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		L77117 Genomic DNA. Translation: AAB98008.1.
PIRD64303.
RefSeqNP_246991.1. NC_000909.1.

3D structure databases

ProteinModelPortalQ60337.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1450866.
GenomeReviewsGene locus MJ0028 in contig L77117_GR.
KEGGmja:MJ_0028.
NMPDRfig|243232.1.peg.28.
TIGRMJ0028.

Phylogenomic databases

HOGENOMHBG577902.
OMAGCCDISD.
ProtClustDBCLSK876040.

Enzyme and pathway databases

BioCycMJAN243232:MJ_0028-MONOMER.

Family and domain databases

InterProIPR000728. AIR_synth.
IPR010918. AIR_synth_C.
IPR016188. PurM_N-like.
IPR006283. ThiL.
[Graphical view]
KOK00946.
PfamPF00586. AIRS. 1 hit.
[Graphical view]
PIRSFPIRSF005303. Thiam_monoph_kin. 1 hit.
SUPFAMSSF56042. AIR_synth_C. 1 hit.
SSF55326. PurM_N-like. 1 hit.
TIGRFAMsTIGR01379. ThiL. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTHIL_METJA
AccessionPrimary (citable) accession number: Q60337
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: November 16, 2011
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Methanococcus jannaschii

Methanococcus jannaschii: entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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