Reviewed, UniProtKB/Swiss-Prot Q60332 (Y021_METJA)

Names and origin

Protein names

Recommended name:
    Uncharacterized protein MJ0021

Gene names

Ordered Locus Names:

MJ0021

Organism

Methanocaldococcus jannaschii (Methanococcus jannaschii) [Complete proteome] [HAMAP]

Taxonomic identifier

2190 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus

Protein attributes

Sequence length	375 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Cofactor	Binds 1 4Fe-4S cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine Potential.
Sequence similarities	Belongs to the organic radical-activating enzymes family.

Ontologies

Keywords
Ligand	4Fe-4S Iron Iron-sulfur Metal-binding S-adenosyl-L-methionine
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW oxygen and reactive oxygen species metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	4 iron, 4 sulfur cluster binding Inferred from electronic annotation. Source: UniProtKB-KW iron ion binding Inferred from electronic annotation. Source: UniProtKB-KW oxidoreductase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 375	375	Uncharacterized protein MJ0021		PRO_0000200544
Sites
	Metal binding	38	1	Iron-sulfur (4Fe-4S-S-AdoMet) Potential
	Metal binding	42	1	Iron-sulfur (4Fe-4S-S-AdoMet) Potential
	Metal binding	45	1	Iron-sulfur (4Fe-4S-S-AdoMet) Potential

Sequences

	Sequence		Length	Mass (Da)
	Q60332-1 [UniParc]. Last modified November 1, 1997. Version 1. Checksum: 5AEA168D21383CC8	FASTA	375	43,446
	10 20 30 40 50 60 MNVEEIEKYL EENFDKLPEG CKQCVKGGKL VLFITGICNN NCYYCPLSEK RKNKDVIYAN 70 80 90 100 110 120 ERLITTVEEA IEEAKLCSSK GVGITGGNPL LKINRTVKFL KALKKEFDEF HAHLYTTPET 130 140 150 160 170 180 VNEENLKLLK EADLDEIRLH PTKIFNEGYD EEYIKFLCNK LNLCNKYIED VGVEIPAIPN 190 200 210 220 230 240 MENEILKLAE AIDGIAKFMN INELEFSEEN YHELEKRGFM PKDDVSNAIA GSEETALKVI 250 260 270 280 290 300 KEFKGDLFIN YCPSVLKDAI QMRNRLINRA KNVAKPYEVI TEDGLLLRGI MIFDNEDDLK 310 320 330 340 350 360 EMAEILEENE IEFEIIDKNI CLNPFILEDI IEEMKRQRFP ITFSAYISEL YPTADALEVE 370 RIPLITKKLK FRRRR

References

[1]

"Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii." Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G., Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R., Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R., Kirkness E.F., Weinstock K.G. , Merrick J.M., Glodek A., Scott J.L., Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R., Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D., Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P., Fraser C.M., Smith H.O., Woese C.R., Venter J.C. Science 273:1058-1073(1996) [PubMed: 8688087] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

Cross-references

Sequence databases
EMBLGenBankDDBJ	L77117 Genomic DNA. Translation: AAB98003.1.
PIR	E64302.
RefSeq	NP_246984.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1450859.
GenomeReviews	Gene locus MJ0021 in contig L77117_GR.
KEGG	mja:MJ0021.
NMPDR	fig|243232.1.peg.21.
TIGR	MJ0021.
Phylogenomic databases
HOGENOM	Q60332.
OMA	HIHLYTS
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR006638. Elp3/MiaB/NifB. IPR001989. Radical_activat_CS. IPR007197. Radical_SAM. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
Pfam	PF04055. Radical_SAM. 1 hit. [Graphical view]
SMART	SM00729. Elp3. 1 hit. [Graphical view]
PROSITE	PS01087. RADICAL_ACTIVATING. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y021_METJA

Accession

Primary (citable) accession number: Q60332

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	November 24, 2009
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)