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Q60316 (FDHB_METJA) Reviewed, UniProtKB/Swiss-Prot

Last modified December 11, 2013. Version 93. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Formate dehydrogenase subunit beta

EC=1.2.1.2
Gene names
Name:fdhB
Ordered Locus Names:MJ0005
OrganismMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) [Reference proteome] [HAMAP]
Taxonomic identifier243232 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus

Protein attributes

Sequence length379 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the oxidation of formate By similarity.

Catalytic activity

Formate + NAD+ = CO2 + NADH.

Cofactor

Binds 2 4Fe-4S clusters Probable.

Subunit structure

Dimer of an alpha and a beta subunit By similarity.

Sequence similarities

Belongs to the FrhB family.

Contains 2 4Fe-4S ferredoxin-type domains.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 379379Formate dehydrogenase subunit beta
PRO_0000159224

Regions

Domain271 – 301314Fe-4S ferredoxin-type 1
Domain321 – 351314Fe-4S ferredoxin-type 2

Sites

Metal binding2801Iron-sulfur (4Fe-4S) By similarity
Metal binding2831Iron-sulfur (4Fe-4S) By similarity
Metal binding2861Iron-sulfur (4Fe-4S) By similarity
Metal binding2901Iron-sulfur (4Fe-4S) By similarity
Metal binding3301Iron-sulfur (4Fe-4S) By similarity
Metal binding3331Iron-sulfur (4Fe-4S) By similarity
Metal binding3361Iron-sulfur (4Fe-4S) By similarity
Metal binding3401Iron-sulfur (4Fe-4S) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q60316 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: 9C257CCAD5547F5A

FASTA37943,014
        10         20         30         40         50         60 
MKYVLIQATD NGILRRAECG GAVTALFKYL LDKKLVDGVL ALKRGEDVYD GIPTFITNSN 

        70         80         90        100        110        120 
ELVETAGSLH CAPTNFGKLI AKYLADKKIA VPAKPCDAMA IRELAKLNQI NLDNVYMIGL 

       130        140        150        160        170        180 
NCGGTISPIT AMKMIELFYE VNPLDVVKEE IDKGKFIIEL KNGEHKAVKI EELEEKGFGR 

       190        200        210        220        230        240 
RKNCQRCEIM IPRMADLACG NWGAEKGWTF VEICSERGRK LVEDAEKDGY IKIKQPSEKA 

       250        260        270        280        290        300 
IQVREKIESI MIKLAKKFQK KHLEEEYPSL EKWKKYWNRC IKCYGCRDNC PLCFCVECSL 

       310        320        330        340        350        360 
EKDYIEEKGK IPPNPLIFQG IRLSHISQSC INCGQCEDAC PMDIPLAYIF HRMQLKIRDT 

       370 
LGYIPGVDNS LPPLFNIER 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L77117 Genomic DNA. Translation: AAB97986.1.
PIRE64300.
RefSeqNP_246968.1. NC_000909.1.

3D structure databases

ProteinModelPortalQ60316.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243232.MJ0005.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB97986; AAB97986; MJ_0005.
GeneID1450844.
KEGGmja:MJ_0005.

Phylogenomic databases

eggNOGCOG1145.
KOK00125.
OMACAPTMFG.
ProtClustDBCLSK876031.

Family and domain databases

InterProIPR001450. 4Fe4S-bd_dom.
IPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
IPR007516. Co_F420_Hydgase/DH_bsu_N.
IPR007525. FrhB_FdhB_C.
IPR009051. Helical_ferredxn.
[Graphical view]
PfamPF00037. Fer4. 1 hit.
PF04432. FrhB_FdhB_C. 1 hit.
PF04422. FrhB_FdhB_N. 1 hit.
[Graphical view]
SUPFAMSSF46548. SSF46548. 1 hit.
PROSITEPS00198. 4FE4S_FER_1. 2 hits.
PS51379. 4FE4S_FER_2. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameFDHB_METJA
AccessionPrimary (citable) accession number: Q60316
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: December 11, 2013
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Methanococcus jannaschii

Methanococcus jannaschii: entries and gene names