Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q602H4 (SYR_METCA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:MCA3089
OrganismMethylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath) [Complete proteome] [HAMAP]
Taxonomic identifier243233 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaMethylococcalesMethylococcaceaeMethylococcus

Protein attributes

Sequence length586 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 586586Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000242043

Regions

Motif128 – 13811"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q602H4 [UniParc].

Last modified November 23, 2004. Version 1.
Checksum: D88EEC95AD29FD56

FASTA58665,782
        10         20         30         40         50         60 
MKKRLETLLR SALERLKTAG DLPADQEVPL QIERTRDPAH GDFAANTAML LAKSARCDPR 

        70         80         90        100        110        120 
RLAEKIRAAL PEDPAVIRTE IAGPGFINFF LDAIAQHRVI TDIHSQGPGF GRSSIGAGQR 

       130        140        150        160        170        180 
VQVEFVSANP TGPLHVGHGR GAAYGAVVAD LLEAAGFDVH REYYVNDAGR QMDILAASVW 

       190        200        210        220        230        240 
LRYLENCGEV LPFPANGYRG EYVRDIASDL YRTQGERYRT SADQVLLGLP PDEPQGGDKE 

       250        260        270        280        290        300 
EYIDAVVSKS KNLLGPERYR EVFNAGLDSI LDDIRDDLGE FGTHYQEWFS ERSLTETGAV 

       310        320        330        340        350        360 
ERALERLKSS GYVYEKDGAQ WFASTRLGDE KDRVLVRENG QTTYFASDVA YHLNKLERGF 

       370        380        390        400        410        420 
DRIVNVWGAD HHGYIPRVKA AIQALGGDAS KLEVLLVQFA VLYRGTERVQ MSTRSGEFVT 

       430        440        450        460        470        480 
LRQLRNEVGK DAARFFYVMR KSDQHMDFDL KLATSRTNEN PVYYVQYAHA RVCSVFRQLD 

       490        500        510        520        530        540 
EKGWARDLGR GMRRLERLCE PHELTLVASL SRYPEVVEQA ALQYAPHHLV HYLRDLAAEF 

       550        560        570        580 
HGYYNSCQFL VEDGDLRDAR LNLIDAVRQV IANGLGLLGV SAPETM 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017282 Genomic DNA. Translation: AAU90811.1.
RefSeqYP_115476.1. NC_002977.6.

3D structure databases

ProteinModelPortalQ602H4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243233.MCA3089.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAU90811; AAU90811; MCA3089.
GeneID3104342.
KEGGmca:MCA3089.
PATRIC22610068. VBIMetCap22254_3125.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMAMEHMGFG.
OrthoDBEOG6JB13C.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_METCA
AccessionPrimary (citable) accession number: Q602H4
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: November 23, 2004
Last modified: May 14, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries