Q60171 (Q60171_GEOSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Cytosine-specific methyltransferase RuleBase RU000417
EC=2.1.1.37 RuleBase RU000417

Gene names

Name:	phi-bsshIIM EMBL AAA96793.1
Synonyms:	mbsshII EMBL CAA62381.1

Organism

Geobacillus stearothermophilus (Bacillus stearothermophilus) EMBL AAA96793.1

Taxonomic identifier

1422 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Geobacillus

Protein attributes

Sequence length	534 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine. RuleBase RU000417
Sequence similarities	Belongs to the C5-methyltransferase family.

Ontologies

Keywords
Biological process	Restriction system RuleBase RU004244
Molecular function	Methyltransferase RuleBase RU000417 EMBL AAA96793.1 Transferase
Gene Ontology (GO)
Biological_process	C-5 methylation of cytosine Inferred from electronic annotation. Source: GOC DNA restriction-modification system Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	DNA (cytosine-5-)-methyltransferase activity Inferred from electronic annotation. Source: EC DNA binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q60171 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 9E08C42B8A86A13B	FASTA	534	58,864
	10 20 30 40 50 60 MTFDVTPQLP DSGLTVAELF AGGGLMAVGL RAAGYNLVWA NDFDKSACAA YRHNLGDHIV 70 80 90 100 110 120 HGDITAIDPA DIPDTDVIAG GPPCQDYSVA GTGAGEEGER GKLVWAYLRI IEAKRPKAFI 130 140 150 160 170 180 FENVKGLITK KHRPTFDALL KQFKIIGYNV SWKLINAWDY GVAQKRERVF IVGIRADLGF 190 200 210 220 230 240 AFEFPEPRPG DYRTQVLRDV IGDLPEPVDT CGRRVKKVER VADMNEPGPT VTTQFRCQTV 250 260 270 280 290 300 EITNHNGGVP AKEYPGHTAS SLEGPAKTIV AGANGVPGGA NCFYPNHERK EISEKALAGY 310 320 330 340 350 360 ERRGGQGGFG FRVNQWDDPS PTIFGRIFNE GKAFVHPGPI ENHDEKSFWT PKSEYTYDQA 370 380 390 400 410 420 NRVQSWDKPS ATIPAHHNSG QPNHPQYANH DRYAVLAKDS DVIPKIPEGA SNRQAAKIEP 430 440 450 460 470 480 DIYWSDYIRE SRENPARTMI GTGKPKIHPT QPRRFTVREC LRIQSVPDWY VLPDDISLSA 490 500 510 520 530 QYRIVGNGIA SRVAYLLGIA LAEQLRAATE SSAIGERLIA DNTDDCANSR KEAV

References

[1]	"M.BssHII: a new multispecific C5-DNA-methyltransferase." Schumann J., Willert J., Wild C., Walter J., Trautner T.A. Gene 157:103-104(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: H3 EMBL CAA62381.1.
[2]	"Cloning and expression of a multispecific methyltransferase gene from the thermophile, Bacillus stearothermophilus H3." Nwankwo D.O., Moran L.S., Perler F.B., Slatko B.E., Wilson G.G., Benner J.S. Mol. Gen. Genet. 0:0-0(1996) Cited for: NUCLEOTIDE SEQUENCE. Strain: H3 EMBL AAA96793.1.
[3]	Schumann J. Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: H3 EMBL CAA62381.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U51733 Genomic DNA. Translation: AAA96793.1. X90873 Genomic DNA. Translation: CAA62381.1.
PIR	S61228. I40424.
3D structure databases
HSSP	HSSP built from PDB template 1DCT based on UniProtKB P20589.
ProteinModelPortal	Q60171.
ModBase	Search...
Protein family/group databases
REBASE	3030. M.BssHIII.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR018117. C5_DNA_meth_AS. IPR001525. C5_MeTfrase. [Graphical view]
PANTHER	PTHR10629. PTHR10629. 1 hit.
Pfam	PF00145. DNA_methylase. 1 hit. [Graphical view]
PRINTS	PR00105. C5METTRFRASE.
TIGRFAMs	TIGR00675. dcm. 1 hit.
PROSITE	PS00094. C5_MTASE_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q60171_GEOSE

Accession

Primary (citable) accession number: Q60171

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	April 3, 2013
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)