UniProtKB - Q600A8 (G6PI_MYCH2)
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Protein
Glucose-6-phosphate isomerase
Gene
pgi
Organism
Mycoplasma hyopneumoniae (strain 232)
Status
Functioni
Catalytic activityi
D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation
: glycolysis Pathwayi
This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotationProteins known to be involved in the 4 steps of the subpathway in this organism are:
- no protein annotated in this organism
- Glucose-6-phosphate isomerase (pgi)
- ATP-dependent 6-phosphofructokinase (pfkA)
- no protein annotated in this organism
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 282 | Proton donorUniRule annotation | 1 | |
Active sitei | 303 | UniRule annotation | 1 | |
Active sitei | 418 | UniRule annotation | 1 |
GO - Molecular functioni
- glucose-6-phosphate isomerase activity Source: UniProtKB-EC
GO - Biological processi
- gluconeogenesis Source: UniProtKB-KW
- glycolytic process Source: UniProtKB-UniPathway
Keywordsi
Molecular function | Isomerase |
Biological process | Gluconeogenesis, Glycolysis |
Enzyme and pathway databases
BioCyci | MHYO295358:G1G11-574-MONOMER. |
UniPathwayi | UPA00109; UER00181. |
Names & Taxonomyi
Protein namesi | Recommended name: Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)Short name: GPIUniRule annotation Alternative name(s): Phosphoglucose isomeraseUniRule annotation Short name: PGIUniRule annotation Phosphohexose isomeraseUniRule annotation Short name: PHIUniRule annotation |
Gene namesi | Name:pgiUniRule annotation Ordered Locus Names:mhp548 |
Organismi | Mycoplasma hyopneumoniae (strain 232) |
Taxonomic identifieri | 295358 [NCBI] |
Taxonomic lineagei | Bacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma › |
Proteomesi |
|
Subcellular locationi
- Cytoplasm UniRule annotation
GO - Cellular componenti
- cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000180680 | 1 – 429 | Glucose-6-phosphate isomeraseAdd BLAST | 429 |
Structurei
3D structure databases
ProteinModelPortali | Q600A8. |
SMRi | Q600A8. |
ModBasei | Search... |
MobiDBi | Search... |
Family & Domainsi
Sequence similaritiesi
Belongs to the GPI family.UniRule annotation
Phylogenomic databases
HOGENOMi | HOG000100403. |
KOi | K01810. |
OMAi | SFIIPDD. |
OrthoDBi | POG091H0EIM. |
Family and domain databases
CDDi | cd05015. SIS_PGI_1. 1 hit. cd05016. SIS_PGI_2. 1 hit. |
HAMAPi | MF_00473. G6P_isomerase. 1 hit. |
InterProi | View protein in InterPro IPR001672. G6P_Isomerase. IPR018189. Phosphoglucose_isomerase_CS. IPR035476. SIS_PGI_1. IPR035482. SIS_PGI_2. |
PANTHERi | PTHR11469. PTHR11469. 1 hit. |
Pfami | View protein in Pfam PF00342. PGI. 1 hit. |
PRINTSi | PR00662. G6PISOMERASE. |
PROSITEi | View protein in PROSITE PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit. PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit. PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit. |
i Sequence
Sequence statusi: Complete.
Q600A8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSLKLEVKTE IKLDYQDFQN QINEFHKRIN DKNSPDIIFL GWNNFPEVAI
60 70 80 90 100
NPQEIARMRK IVENLHQNSI NVLVVIGIGG SYLGAKAALD FILGLGPFEN
110 120 130 140 150
KPEVIFLGNS LSSTDLYQKI EYLKTKNFAI NVISKSGSTI EPAITFQILY
160 170 180 190 200
QFLIDQIGEK LAKTRTFVTT SIKSGELLEI AKSNELEIFE VIESIGGRFS
210 220 230 240 250
VLSSVGFFPL LFAKINVDEI IQGAIKAHKK YSTSSISQNL AYKYALFRFL
260 270 280 290 300
MYKNFNYKTE ILISYEPFLI YFNEWWKQLF GESEGKNLKG LFPASAIFTT
310 320 330 340 350
DLHSLGQFIQ DGSKNFFQTI IYIKKPKFDL GIKKLVQFNT KINKLSGKTV
360 370 380 390 400
SEINFQAFLA TTLAHSSYGN NPNLVLEIAD SSPKTFGHLV MFFEKACAMS
410 420
AYLLGVNPFD QPGVESYKNE LAKNLGWDR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE017332 Genomic DNA. Translation: AAV27948.1. |
RefSeqi | WP_011206381.1. NC_006360.1. |
Genome annotation databases
EnsemblBacteriai | AAV27948; AAV27948; mhp548. |
KEGGi | mhy:mhp548. |
Similar proteinsi
Entry informationi
Entry namei | G6PI_MYCH2 | |
Accessioni | Q600A8Primary (citable) accession number: Q600A8 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 29, 2005 |
Last sequence update: | November 23, 2004 | |
Last modified: | February 28, 2018 | |
This is version 78 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |