Reviewed, UniProtKB/Swiss-Prot Q60041 (XYNB_THENE)

Names and origin

Protein names

Recommended name:
    Endo-1,4-beta-xylanase B
      Short name=Xylanase B
    EC=3.2.1.8
Alternative name(s):
    1,4-beta-D-xylan xylanohydrolase B

Gene names

Name:

xynB

Organism

Thermotoga neapolitana

Taxonomic identifier

2337 [NCBI]

Taxonomic lineage

Bacteria › Thermotogae › Thermotogales › Thermotogaceae › Thermotoga

Protein attributes

Sequence length	346 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.
Sequence similarities	Belongs to the glycosyl hydrolase 10 (cellulase F) family.

Ontologies

Keywords
Biological process	Xylan degradation
Domain	Signal
Molecular function	Glycosidase Hydrolase
Gene Ontology (GO)
Biological process	xylan catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	cation binding Inferred from electronic annotation. Source: InterPro endo-1,4-beta-xylanase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 19	19	Potential
	Chain	20 – 346	327	Endo-1,4-beta-xylanase B		PRO_0000007988
Sites
	Active site	153	1	Proton donor By similarity
	Active site	259	1	Nucleophile By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q60041-1 [UniParc]. Last modified November 1, 1997. Version 1. Checksum: 5E96C39D46173595	FASTA	346	40,338
	10 20 30 40 50 60 MKGLPALLLL LIGCVSSFGS QDVPLRVLAE KLNIHIGFAA GNNFWSLPDA EKYMEVAKRE 70 80 90 100 110 120 FNILTPGNQM KWDTIHPERN RYNFEPAEKH VEFALKNDMI VHGHTLVWHN QLPGWLTGQE 130 140 150 160 170 180 WSKEELLNIL EDHVKTVVSH FRGRVKIWDV VNEAVSDSGT YRESIWYRTI GPEYIEKALI 190 200 210 220 230 240 WAKEADPDAI LIYNDYNIEE INAKSNFVYN MIKNLREKGV PIDGIGFQMH IDYRGINYES 250 260 270 280 290 300 FKKNLERFAE LGLQIYITEM DRGFPLGGSV GYYLKKQAEV YRRIFEICLD NPAVRAIQFW 310 320 330 340 GFTDKYSWVP GFFKGYGKAL IFDENYNPKP CYFAIRELME EKLKER

References

[1]	Zverlov V., Piotukh K., Velikodvorskaja G., Goetz F., Borriss R. Submitted (DEC-1995) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: Z2706-MC24.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z49961 Genomic DNA. Translation: CAA90235.1.
3D structure databases
SMR	Q60041. Positions 23-346.
ModBase	Search...
Protein family/group databases
CAZy	GH10. Glycoside Hydrolase Family 10.
Enzyme and pathway databases
BRENDA	3.2.1.8. 1590.
Family and domain databases
InterPro	IPR001000. Glyco_hydro_10. IPR017853. Glyco_hydro_catalytic_core. IPR013781. Glyco_hydro_sg_catalytic. [Graphical view]
Gene3D	G3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit.
Pfam	PF00331. Glyco_hydro_10. 1 hit. [Graphical view]
PRINTS	PR00134. GLHYDRLASE10.
SMART	SM00633. Glyco_10. 1 hit. [Graphical view]
PROSITE	PS00591. GLYCOSYL_HYDROL_F10. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

XYNB_THENE

Accession

Primary (citable) accession number: Q60041

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	November 24, 2009
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)