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Q60036 (SODF_METTM) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Superoxide dismutase [Fe]

EC=1.15.1.1
Gene names
Name:sod
Synonyms:sodA
Ordered Locus Names:MTBMA_c06110
OrganismMethanothermobacter marburgensis (strain DSM 2133 / 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum) [Complete proteome] [HAMAP]
Taxonomic identifier79929 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanobacteriaMethanobacterialesMethanobacteriaceaeMethanothermobacter

Protein attributes

Sequence length202 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

Catalytic activity

2 superoxide + 2 H+ = O2 + H2O2.

Cofactor

Binds 1 iron ion per subunit By similarity.

Subunit structure

Homotetramer.

Sequence similarities

Belongs to the iron/manganese superoxide dismutase family.

Ontologies

Keywords
   LigandIron
Metal-binding
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processsuperoxide metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

superoxide dismutase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 202202Superoxide dismutase [Fe]
PRO_0000160007

Sites

Metal binding301Iron By similarity
Metal binding781Iron By similarity
Metal binding1641Iron By similarity
Metal binding1681Iron By similarity

Sequences

Sequence LengthMass (Da)Tools
Q60036 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 5C4FBE27EEE63223

FASTA20223,829
        10         20         30         40         50         60 
MEKKFYELPE LPYPYDALEP YISEEQLRIH HEKHHQAYVD GANGVLRKLD DARENGEEVD 

        70         80         90        100        110        120 
IKAALKELSF HVGGYVLHLF FWGNMGPADE CGGEPDGRLA EYIEKDFGSF QRFKKEFSQA 

       130        140        150        160        170        180 
AVSAEGSGWA VLTYCQRTDR LFIMQVEKHN VNVIPHFRIL MVLDVWEHAY YIDYRNVRPD 

       190        200 
YVEAFWNIVN WKEVEKRFDD LF 

« Hide

References

« Hide 'large scale' references
[1]"Characterization of the superoxide dismutase gene and its upstream region from Methanobacterium thermoautotrophicum Marburg."
Meile L., Fischer K., Leisinger T.
FEMS Microbiol. Lett. 128:247-253(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: DSM 2133 / 14651 / NBRC 100331 / OCM 82 / Marburg.
[2]"Complete genome sequence of Methanothermobacter marburgensis, a methanoarchaeon model organism."
Liesegang H., Kaster A.K., Wiezer A., Goenrich M., Wollherr A., Seedorf H., Gottschalk G., Thauer R.K.
J. Bacteriol. 192:5850-5851(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 2133 / 14651 / NBRC 100331 / OCM 82 / Marburg.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X74264 Genomic DNA. Translation: CAA52323.1.
CP001710 Genomic DNA. Translation: ADL58206.1.
PIRS51097.
RefSeqYP_003849519.1. NC_014408.1.

3D structure databases

ProteinModelPortalQ60036.
SMRQ60036. Positions 2-202.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADL58206; ADL58206; MTBMA_c06110.
GeneID9704319.
KEGGmmg:MTBMA_c06110.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000013583.
KOK04564.
OMAWNVFNWD.
ProtClustDBCLSK2750246.

Enzyme and pathway databases

BioCycMMAR79929:GH5J-614-MONOMER.

Family and domain databases

InterProIPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
[Graphical view]
PANTHERPTHR11404. PTHR11404. 1 hit.
PfamPF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
[Graphical view]
PIRSFPIRSF000349. SODismutase. 1 hit.
PRINTSPR01703. MNSODISMTASE.
SUPFAMSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEPS00088. SOD_MN. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSODF_METTM
AccessionPrimary (citable) accession number: Q60036
Secondary accession number(s): D9PVF8
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: November 1, 1996
Last modified: October 16, 2013
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families