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Protein

Aspartate aminotransferase

Gene

aspC

Organism
Streptomyces virginiae
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.

Cofactori

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei36Aspartate; via amide nitrogenBy similarity1
Binding sitei123AspartateBy similarity1
Binding sitei173AspartateBy similarity1
Binding sitei371AspartateBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminotransferase, Transferase
LigandPyridoxal phosphate

Names & Taxonomyi

Protein namesi
Recommended name:
Aspartate aminotransferase (EC:2.6.1.1)
Short name:
AspAT
Alternative name(s):
Transaminase A
Gene namesi
Name:aspC
Synonyms:aat
OrganismiStreptomyces virginiae
Taxonomic identifieri1961 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001238531 – 397Aspartate aminotransferaseAdd BLAST397

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei236N6-(pyridoxal phosphate)lysineBy similarity1

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ60013
SMRiQ60013
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.40.640.10, 1 hit
3.90.1150.10, 2 hits
InterProiView protein in InterPro
IPR004839 Aminotransferase_I/II
IPR004838 NHTrfase_class1_PyrdxlP-BS
IPR015424 PyrdxlP-dep_Trfase
IPR015422 PyrdxlP-dep_Trfase_dom1
IPR015421 PyrdxlP-dep_Trfase_major
PfamiView protein in Pfam
PF00155 Aminotran_1_2, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit
PROSITEiView protein in PROSITE
PS00105 AA_TRANSFER_CLASS_1, 1 hit

Sequencei

Sequence statusi: Complete.

Q60013-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSARIGAISE SATLAVDAKA KALKAAGRPV IGFGAGEPDF PTPDYIVEAA
60 70 80 90 100
VEACRNPKYH RYTPAGGLPE LKAAIAAKTL RDSGYEVEAS QVLVTNGGKQ
110 120 130 140 150
AIYEAFAAIL DPGDEVIVPA PYWTTYPESI RLAGGVPVDV VADETTGYRV
160 170 180 190 200
SVEQLEAART ERTKVVLFVS PSNPTGSVYS EADAKAIGEW AAEHGLWVLT
210 220 230 240 250
DEIYEHLVYG EAKFTSLPVL VPALRDKCII VNGVAKTYAM TGWRVGWVIA
260 270 280 290 300
PQDVIKAATN LQSHATSNVS NVAQVAALAA VSGNLDAVAE MRKAFDRRRQ
310 320 330 340 350
TMVKMLNEID GVFCPTPEGA FYAYPSVKEL LGKEIRGKRP QSSVELAALI
360 370 380 390
LDEVEVAVVP GEAFGTPGYL RLSYALGDED LVEGVSRIQK LLAEAKA
Length:397
Mass (Da):42,381
Last modified:November 1, 1996 - v1
Checksum:iEEFEDCEB7D923065
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D50624 Genomic DNA Translation: BAA09299.1
PIRiT11786

Similar proteinsi

Entry informationi

Entry nameiAAT_STRVG
AccessioniPrimary (citable) accession number: Q60013
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1996
Last modified: April 25, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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