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Q60013 (AAT_STRVG) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Aspartate aminotransferase

Short name=AspAT
EC=2.6.1.1
Alternative name(s):
Transaminase A
Gene names
Name:aspC
Synonyms:aat
OrganismStreptomyces virginiae
Taxonomic identifier1961 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

Protein attributes

Sequence length397 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.

Cofactor

Pyridoxal phosphate By similarity.

Subunit structure

Homodimer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 397397Aspartate aminotransferase
PRO_0000123853

Sites

Binding site361Aspartate; via amide nitrogen By similarity
Binding site1231Aspartate By similarity
Binding site1731Aspartate By similarity
Binding site3711Aspartate By similarity

Amino acid modifications

Modified residue2361N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q60013 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: EEFEDCEB7D923065

FASTA39742,381
        10         20         30         40         50         60 
MSARIGAISE SATLAVDAKA KALKAAGRPV IGFGAGEPDF PTPDYIVEAA VEACRNPKYH 

        70         80         90        100        110        120 
RYTPAGGLPE LKAAIAAKTL RDSGYEVEAS QVLVTNGGKQ AIYEAFAAIL DPGDEVIVPA 

       130        140        150        160        170        180 
PYWTTYPESI RLAGGVPVDV VADETTGYRV SVEQLEAART ERTKVVLFVS PSNPTGSVYS 

       190        200        210        220        230        240 
EADAKAIGEW AAEHGLWVLT DEIYEHLVYG EAKFTSLPVL VPALRDKCII VNGVAKTYAM 

       250        260        270        280        290        300 
TGWRVGWVIA PQDVIKAATN LQSHATSNVS NVAQVAALAA VSGNLDAVAE MRKAFDRRRQ 

       310        320        330        340        350        360 
TMVKMLNEID GVFCPTPEGA FYAYPSVKEL LGKEIRGKRP QSSVELAALI LDEVEVAVVP 

       370        380        390 
GEAFGTPGYL RLSYALGDED LVEGVSRIQK LLAEAKA 

« Hide

References

[1]"Gene organization in the ada-rplL region of Streptomyces virginiae."
Katayama M., Sakai Y., Okamoto S., Ihara F., Nihira T., Yamada Y.
Gene 171:135-136(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D50624 Genomic DNA. Translation: BAA09299.1.
PIRT11786.

3D structure databases

ProteinModelPortalQ60013.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProIPR004839. Aminotransferase_I/II.
IPR004838. NHTrfase_class1_PyrdxlP-BS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMSSF53383. SSF53383. 1 hit.
PROSITEPS00105. AA_TRANSFER_CLASS_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAAT_STRVG
AccessionPrimary (citable) accession number: Q60013
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1996
Last modified: October 16, 2013
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families