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Q5ZZ88

- Q5ZZ88_LEGPH

UniProt

Q5ZZ88 - Q5ZZ88_LEGPH

Protein

Thiol:disulfide interchange protein

Gene

dsbA

Organism
Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 75 (01 Oct 2014)
      Sequence version 1 (23 Nov 2004)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei137 – 1371Sulfate; via amide nitrogenImported

    GO - Molecular functioni

    1. protein disulfide oxidoreductase activity Source: InterPro

    GO - Biological processi

    1. cell redox homeostasis Source: InterPro

    Enzyme and pathway databases

    BioCyciLPNE272624:GHDI-123-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Thiol:disulfide interchange proteinUniRule annotation
    Gene namesi
    Name:dsbAImported
    Ordered Locus Names:lpg0123Imported
    OrganismiLegionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)Imported
    Taxonomic identifieri272624 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesLegionellaceaeLegionella
    ProteomesiUP000000609: Chromosome

    Subcellular locationi

    Periplasm UniRule annotation

    GO - Cellular componenti

    1. periplasmic space Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    PeriplasmUniRule annotation

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi66 ↔ 69Redox-activeUniRule annotation

    Keywords - PTMi

    Disulfide bondUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi272624.lpg0123.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4JRRX-ray1.88A/B/C33-217[»]
    ProteinModelPortaliQ5ZZ88.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the thioredoxin family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0526.
    HOGENOMiHOG000265316.
    KOiK03673.
    OMAiQKPRITR.
    OrthoDBiEOG68Q0Q6.

    Family and domain databases

    Gene3Di3.40.30.10. 1 hit.
    InterProiIPR001853. DSBA-like_thioredoxin_dom.
    IPR023205. DsbA/DsbL.
    IPR012336. Thioredoxin-like_fold.
    IPR017937. Thioredoxin_CS.
    [Graphical view]
    PfamiPF01323. DSBA. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001488. Tdi_protein. 1 hit.
    SUPFAMiSSF52833. SSF52833. 1 hit.
    PROSITEiPS00194. THIOREDOXIN_1. 1 hit.
    PS51352. THIOREDOXIN_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5ZZ88-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLIIFKGYIE ELTMFKKLIA LLFLMPMTAL ATQFIEGKDY QTVASAQLST    50
    NKDKTPLITE FFSYGCPWCY KIDAPLNDWA TRMGKGAHLE RVPVVFKPNW 100
    DLYAKAYYTA KTLAMSDKMN PILFKAIQED KNPLATKQSM VDFFVAHGVD 150
    REIAKSAFEN SPTIDMRVNS GMSLMAHYQI NAVPAFVVNN KYKTDLQMAG 200
    SEERLFEILN YLVRKSA 217
    Length:217
    Mass (Da):24,712
    Last modified:November 23, 2004 - v1
    Checksum:i1F6D7B3A3E4D5A0C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017354 Genomic DNA. Translation: AAU26230.1.
    RefSeqiWP_010945884.1. NC_002942.5.
    YP_094177.1. NC_002942.5.

    Genome annotation databases

    EnsemblBacteriaiAAU26230; AAU26230; lpg0123.
    GeneIDi3079919.
    KEGGilpn:lpg0123.
    PATRICi22327166. VBILegPne29832_0129.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017354 Genomic DNA. Translation: AAU26230.1 .
    RefSeqi WP_010945884.1. NC_002942.5.
    YP_094177.1. NC_002942.5.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4JRR X-ray 1.88 A/B/C 33-217 [» ]
    ProteinModelPortali Q5ZZ88.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272624.lpg0123.

    Protocols and materials databases

    DNASUi 3079919.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAU26230 ; AAU26230 ; lpg0123 .
    GeneIDi 3079919.
    KEGGi lpn:lpg0123.
    PATRICi 22327166. VBILegPne29832_0129.

    Phylogenomic databases

    eggNOGi COG0526.
    HOGENOMi HOG000265316.
    KOi K03673.
    OMAi QKPRITR.
    OrthoDBi EOG68Q0Q6.

    Enzyme and pathway databases

    BioCyci LPNE272624:GHDI-123-MONOMER.

    Family and domain databases

    Gene3Di 3.40.30.10. 1 hit.
    InterProi IPR001853. DSBA-like_thioredoxin_dom.
    IPR023205. DsbA/DsbL.
    IPR012336. Thioredoxin-like_fold.
    IPR017937. Thioredoxin_CS.
    [Graphical view ]
    Pfami PF01323. DSBA. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001488. Tdi_protein. 1 hit.
    SUPFAMi SSF52833. SSF52833. 1 hit.
    PROSITEi PS00194. THIOREDOXIN_1. 1 hit.
    PS51352. THIOREDOXIN_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Philadelphia 1 / ATCC 33152 / DSM 7513Imported.
    2. "Crystal structure of disulfide bond oxidoreductase DsbA1 from Legionella pneumophila."
      Shumilin I.A., Jameson-Lee M., Cymborowski M., Domagalski M.J., Chertihin O., Kpadeh Z.Z., Yeh A.J., Hoffman P.S., Anderson W.F., Minor W.
      Submitted (MAR-2013) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.88 ANGSTROMS) OF 33-217.

    Entry informationi

    Entry nameiQ5ZZ88_LEGPH
    AccessioniPrimary (citable) accession number: Q5ZZ88
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 23, 2004
    Last sequence update: November 23, 2004
    Last modified: October 1, 2014
    This is version 75 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3