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Q5ZZ88

- Q5ZZ88_LEGPH

UniProt

Q5ZZ88 - Q5ZZ88_LEGPH

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Protein
Thiol:disulfide interchange protein
Gene
dsbA, lpg0123
Organism
Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei137 – 1371Sulfate; via amide nitrogenImported

GO - Molecular functioni

  1. protein disulfide oxidoreductase activity Source: InterPro

GO - Biological processi

  1. cell redox homeostasis Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

BioCyciLPNE272624:GHDI-123-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thiol:disulfide interchange proteinUniRule annotation
Gene namesi
Name:dsbAImported
Ordered Locus Names:lpg0123Imported
OrganismiLegionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)Imported
Taxonomic identifieri272624 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesLegionellaceaeLegionella
ProteomesiUP000000609: Chromosome

Subcellular locationi

Periplasm By similarity UniRule annotation

GO - Cellular componenti

  1. periplasmic space Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

PeriplasmUniRule annotation

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi66 ↔ 69Redox-active By similarityUniRule annotation

Keywords - PTMi

Disulfide bondUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi272624.lpg0123.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4JRRX-ray1.88A/B/C33-217[»]
ProteinModelPortaliQ5ZZ88.

Family & Domainsi

Sequence similaritiesi

Belongs to the thioredoxin family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0526.
HOGENOMiHOG000265316.
KOiK03673.
OMAiQKPRITR.
OrthoDBiEOG68Q0Q6.

Family and domain databases

Gene3Di3.40.30.10. 1 hit.
InterProiIPR001853. DSBA-like_thioredoxin_dom.
IPR023205. DsbA/DsbL.
IPR012336. Thioredoxin-like_fold.
IPR017937. Thioredoxin_CS.
[Graphical view]
PfamiPF01323. DSBA. 1 hit.
[Graphical view]
PIRSFiPIRSF001488. Tdi_protein. 1 hit.
SUPFAMiSSF52833. SSF52833. 1 hit.
PROSITEiPS00194. THIOREDOXIN_1. 1 hit.
PS51352. THIOREDOXIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5ZZ88-1 [UniParc]FASTAAdd to Basket

« Hide

MLIIFKGYIE ELTMFKKLIA LLFLMPMTAL ATQFIEGKDY QTVASAQLST    50
NKDKTPLITE FFSYGCPWCY KIDAPLNDWA TRMGKGAHLE RVPVVFKPNW 100
DLYAKAYYTA KTLAMSDKMN PILFKAIQED KNPLATKQSM VDFFVAHGVD 150
REIAKSAFEN SPTIDMRVNS GMSLMAHYQI NAVPAFVVNN KYKTDLQMAG 200
SEERLFEILN YLVRKSA 217
Length:217
Mass (Da):24,712
Last modified:November 23, 2004 - v1
Checksum:i1F6D7B3A3E4D5A0C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017354 Genomic DNA. Translation: AAU26230.1.
RefSeqiWP_010945884.1. NC_002942.5.
YP_094177.1. NC_002942.5.

Genome annotation databases

EnsemblBacteriaiAAU26230; AAU26230; lpg0123.
GeneIDi3079919.
KEGGilpn:lpg0123.
PATRICi22327166. VBILegPne29832_0129.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017354 Genomic DNA. Translation: AAU26230.1 .
RefSeqi WP_010945884.1. NC_002942.5.
YP_094177.1. NC_002942.5.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4JRR X-ray 1.88 A/B/C 33-217 [» ]
ProteinModelPortali Q5ZZ88.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272624.lpg0123.

Protocols and materials databases

DNASUi 3079919.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAU26230 ; AAU26230 ; lpg0123 .
GeneIDi 3079919.
KEGGi lpn:lpg0123.
PATRICi 22327166. VBILegPne29832_0129.

Phylogenomic databases

eggNOGi COG0526.
HOGENOMi HOG000265316.
KOi K03673.
OMAi QKPRITR.
OrthoDBi EOG68Q0Q6.

Enzyme and pathway databases

BioCyci LPNE272624:GHDI-123-MONOMER.

Family and domain databases

Gene3Di 3.40.30.10. 1 hit.
InterProi IPR001853. DSBA-like_thioredoxin_dom.
IPR023205. DsbA/DsbL.
IPR012336. Thioredoxin-like_fold.
IPR017937. Thioredoxin_CS.
[Graphical view ]
Pfami PF01323. DSBA. 1 hit.
[Graphical view ]
PIRSFi PIRSF001488. Tdi_protein. 1 hit.
SUPFAMi SSF52833. SSF52833. 1 hit.
PROSITEi PS00194. THIOREDOXIN_1. 1 hit.
PS51352. THIOREDOXIN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Philadelphia 1 / ATCC 33152 / DSM 7513.
  2. "Crystal structure of disulfide bond oxidoreductase DsbA1 from Legionella pneumophila."
    Shumilin I.A., Jameson-Lee M., Cymborowski M., Domagalski M.J., Chertihin O., Kpadeh Z.Z., Yeh A.J., Hoffman P.S., Anderson W.F., Minor W.
    Submitted (MAR-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.88 ANGSTROMS) OF 33-217.

Entry informationi

Entry nameiQ5ZZ88_LEGPH
AccessioniPrimary (citable) accession number: Q5ZZ88
Entry historyi
Integrated into UniProtKB/TrEMBL: November 23, 2004
Last sequence update: November 23, 2004
Last modified: September 3, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome

External Data

Dasty 3

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