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Q5ZZ88

- Q5ZZ88_LEGPH

UniProt

Q5ZZ88 - Q5ZZ88_LEGPH

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Protein

Thiol:disulfide interchange protein

Gene

dsbA

Organism
Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei137 – 1371Sulfate; via amide nitrogenImported

GO - Molecular functioni

  1. protein disulfide oxidoreductase activity Source: InterPro

GO - Biological processi

  1. cell redox homeostasis Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

BioCyciLPNE272624:GHDI-123-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thiol:disulfide interchange proteinUniRule annotation
Gene namesi
Name:dsbAImported
Ordered Locus Names:lpg0123Imported
OrganismiLegionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)Imported
Taxonomic identifieri272624 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesLegionellaceaeLegionella
ProteomesiUP000000609: Chromosome

Subcellular locationi

Periplasm UniRule annotation

GO - Cellular componenti

  1. periplasmic space Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

PeriplasmUniRule annotation

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi66 ↔ 69Redox-activeUniRule annotation

Keywords - PTMi

Disulfide bondUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi272624.lpg0123.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4JRRX-ray1.88A/B/C33-217[»]
ProteinModelPortaliQ5ZZ88.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thioredoxin family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0526.
HOGENOMiHOG000265316.
KOiK03673.
OMAiQKPRITR.
OrthoDBiEOG68Q0Q6.

Family and domain databases

Gene3Di3.40.30.10. 1 hit.
InterProiIPR001853. DSBA-like_thioredoxin_dom.
IPR023205. DsbA/DsbL.
IPR012336. Thioredoxin-like_fold.
IPR017937. Thioredoxin_CS.
[Graphical view]
PfamiPF01323. DSBA. 1 hit.
[Graphical view]
PIRSFiPIRSF001488. Tdi_protein. 1 hit.
SUPFAMiSSF52833. SSF52833. 1 hit.
PROSITEiPS00194. THIOREDOXIN_1. 1 hit.
PS51352. THIOREDOXIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5ZZ88-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLIIFKGYIE ELTMFKKLIA LLFLMPMTAL ATQFIEGKDY QTVASAQLST
60 70 80 90 100
NKDKTPLITE FFSYGCPWCY KIDAPLNDWA TRMGKGAHLE RVPVVFKPNW
110 120 130 140 150
DLYAKAYYTA KTLAMSDKMN PILFKAIQED KNPLATKQSM VDFFVAHGVD
160 170 180 190 200
REIAKSAFEN SPTIDMRVNS GMSLMAHYQI NAVPAFVVNN KYKTDLQMAG
210
SEERLFEILN YLVRKSA
Length:217
Mass (Da):24,712
Last modified:November 23, 2004 - v1
Checksum:i1F6D7B3A3E4D5A0C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017354 Genomic DNA. Translation: AAU26230.1.
RefSeqiYP_094177.1. NC_002942.5.

Genome annotation databases

EnsemblBacteriaiAAU26230; AAU26230; lpg0123.
GeneIDi19831690.
KEGGilpn:lpg0123.
PATRICi22327166. VBILegPne29832_0129.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017354 Genomic DNA. Translation: AAU26230.1 .
RefSeqi YP_094177.1. NC_002942.5.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4JRR X-ray 1.88 A/B/C 33-217 [» ]
ProteinModelPortali Q5ZZ88.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272624.lpg0123.

Protocols and materials databases

DNASUi 3079919.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAU26230 ; AAU26230 ; lpg0123 .
GeneIDi 19831690.
KEGGi lpn:lpg0123.
PATRICi 22327166. VBILegPne29832_0129.

Phylogenomic databases

eggNOGi COG0526.
HOGENOMi HOG000265316.
KOi K03673.
OMAi QKPRITR.
OrthoDBi EOG68Q0Q6.

Enzyme and pathway databases

BioCyci LPNE272624:GHDI-123-MONOMER.

Family and domain databases

Gene3Di 3.40.30.10. 1 hit.
InterProi IPR001853. DSBA-like_thioredoxin_dom.
IPR023205. DsbA/DsbL.
IPR012336. Thioredoxin-like_fold.
IPR017937. Thioredoxin_CS.
[Graphical view ]
Pfami PF01323. DSBA. 1 hit.
[Graphical view ]
PIRSFi PIRSF001488. Tdi_protein. 1 hit.
SUPFAMi SSF52833. SSF52833. 1 hit.
PROSITEi PS00194. THIOREDOXIN_1. 1 hit.
PS51352. THIOREDOXIN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Philadelphia 1 / ATCC 33152 / DSM 7513Imported.
  2. "Crystal structure of disulfide bond oxidoreductase DsbA1 from Legionella pneumophila."
    Shumilin I.A., Jameson-Lee M., Cymborowski M., Domagalski M.J., Chertihin O., Kpadeh Z.Z., Yeh A.J., Hoffman P.S., Anderson W.F., Minor W.
    Submitted (MAR-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.88 ANGSTROMS) OF 33-217.

Entry informationi

Entry nameiQ5ZZ88_LEGPH
AccessioniPrimary (citable) accession number: Q5ZZ88
Entry historyi
Integrated into UniProtKB/TrEMBL: November 23, 2004
Last sequence update: November 23, 2004
Last modified: October 29, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome, Reference proteomeImported

External Data

Dasty 3