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Q5ZXH2

- G6PI_LEGPH

UniProt

Q5ZXH2 - G6PI_LEGPH

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 2 (29 Mar 2005)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei352 – 3521Proton donorUniRule annotation
    Active sitei383 – 3831UniRule annotation
    Active sitei487 – 4871UniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    BioCyciLPNE272624:GHDI-758-MONOMER.
    UniPathwayiUPA00109; UER00181.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
    Short name:
    GPIUniRule annotation
    Alternative name(s):
    Phosphoglucose isomeraseUniRule annotation
    Short name:
    PGIUniRule annotation
    Phosphohexose isomeraseUniRule annotation
    Short name:
    PHIUniRule annotation
    Gene namesi
    Name:pgiUniRule annotation
    Ordered Locus Names:lpg0759
    OrganismiLegionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)
    Taxonomic identifieri272624 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesLegionellaceaeLegionella
    ProteomesiUP000000609: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 499499Glucose-6-phosphate isomerasePRO_0000180664Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi272624.lpg0759.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5ZXH2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0166.
    HOGENOMiHOG000261370.
    KOiK01810.
    OMAiNCHFVAN.
    OrthoDBiEOG64R61J.

    Family and domain databases

    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5ZXH2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIRNSMKSHT ELLSWNLLQK EADRVRLNSD SLTCVVPDSN NYESSKQINC    50
    IEYDYSRQRV NRTIIDLLID LANEVKLQEK IDNLINGKKI NISENRPALH 100
    TALRDLGNKS IMIDGLDIMS AVINTREKIK VISNQIREKK WLGHSGLPIT 150
    DIVNIGIGGS DLGPRVCINA LSNYISKEFN YHFISDVDPA SFNDVIAKIN 200
    PQTTLFIVSS KSFTTKETLL NARKAFALYE DTASIDQHFI AVTAHPERAY 250
    QMGIKTVLPI WDWVGGRFSF CSAVNLITAI AIGYEQFVEL LAGAHDVDTH 300
    VQFTDFKNNI PVLMALIGIW NNNFLNIHNL LILTYSKKLE YFVPYVQQLD 350
    MESNGKSIDV NGSMVDYATG PIVWGGLGNQ AQHSYFQLLC QGTHRCVGDF 400
    ITLKTNDEHE INSMCHYKMK VLSEGIQTIE NPYGYIPGNM PMNHLILSDC 450
    SPYTLGALVA LYEHKIFVQS VIWNINPFDQ PGIESAKSAH REITLSSES 499
    Length:499
    Mass (Da):56,152
    Last modified:March 29, 2005 - v2
    Checksum:i9049F98135DA80EB
    GO

    Sequence cautioni

    The sequence AAU26848.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017354 Genomic DNA. Translation: AAU26848.1. Different initiation.
    RefSeqiYP_094795.1. NC_002942.5.

    Genome annotation databases

    EnsemblBacteriaiAAU26848; AAU26848; lpg0759.
    GeneIDi3080069.
    KEGGilpn:lpg0759.
    PATRICi22328508. VBILegPne29832_0784.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017354 Genomic DNA. Translation: AAU26848.1 . Different initiation.
    RefSeqi YP_094795.1. NC_002942.5.

    3D structure databases

    ProteinModelPortali Q5ZXH2.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272624.lpg0759.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAU26848 ; AAU26848 ; lpg0759 .
    GeneIDi 3080069.
    KEGGi lpn:lpg0759.
    PATRICi 22328508. VBILegPne29832_0784.

    Phylogenomic databases

    eggNOGi COG0166.
    HOGENOMi HOG000261370.
    KOi K01810.
    OMAi NCHFVAN.
    OrthoDBi EOG64R61J.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    BioCyci LPNE272624:GHDI-758-MONOMER.

    Family and domain databases

    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Philadelphia 1 / ATCC 33152 / DSM 7513.

    Entry informationi

    Entry nameiG6PI_LEGPH
    AccessioniPrimary (citable) accession number: Q5ZXH2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 29, 2005
    Last sequence update: March 29, 2005
    Last modified: October 1, 2014
    This is version 61 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3