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Q5ZWR3 (TYPH_LEGPH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative thymidine phosphorylase

EC=2.4.2.4
Alternative name(s):
TdRPase
Gene names
Ordered Locus Names:lpg1022
OrganismLegionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513) [Complete proteome] [HAMAP]
Taxonomic identifier272624 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaLegionellalesLegionellaceaeLegionella

Protein attributes

Sequence length517 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate. HAMAP-Rule MF_00703

Sequence similarities

Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 517517Putative thymidine phosphorylase HAMAP-Rule MF_00703
PRO_0000225647

Sequences

Sequence LengthMass (Da)Tools
Q5ZWR3 [UniParc].

Last modified November 23, 2004. Version 1.
Checksum: 3903064A69DFB546

FASTA51755,296
        10         20         30         40         50         60 
MHDSFLSANG GFVVSKKTPH GLRLKHLGIK TYHEAIIYMR EDCHVCHSEG FEVQTRIQVT 

        70         80         90        100        110        120 
LGSRSIIATL NVVTSELLQP GEAGLSDYAW ESLHAKEGDE IQVSHPKPLE SLSYVHAKIY 

       130        140        150        160        170        180 
GNELSFEQMK VIIDDVLSGR LSDVQISAFL AASGAGRLTR TEVMKLTKAM IDSGDRLSWP 

       190        200        210        220        230        240 
SPLVVDKHCV GGLPGNRTTL IVVPIVASFG LMIPKTSSRA ITSPAGTADT METLAPVHLS 

       250        260        270        280        290        300 
PQKMRQVVEQ ENGCIVWGGA VSLSPADDVL IRVERAIDLD SEGQLVASIL SKKIATGATH 

       310        320        330        340        350        360 
AVIDIPVGPT AKVRNQSMAL LLKQSLEEVG NELGLVVRAL FTDGSQPVGH GIGPSLEARD 

       370        380        390        400        410        420 
VLAVLQGLPD APNDLRERAL TLAGAALECS SKVPPGLGKS IATQLLESGQ AFKKFQAICE 

       430        440        450        460        470        480 
AQGGMRELTK ARFTYPVVAA KEGKVSLIDN RKLAKIAKLA GAPKSKSAGI DLHAHVGESV 

       490        500        510 
EQGEPLFTIH SESLGELHYA CDLLRDKQDI IILGENP 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017354 Genomic DNA. Translation: AAU27108.1.
RefSeqYP_095055.1. NC_002942.5.

3D structure databases

ProteinModelPortalQ5ZWR3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272624.lpg1022.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAU27108; AAU27108; lpg1022.
GeneID3078614.
KEGGlpn:lpg1022.
PATRIC22329070. VBILegPne29832_1061.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0213.
HOGENOMHOG000252767.
KOK00758.
OMAESVPGFH.
OrthoDBEOG61ZTGG.

Enzyme and pathway databases

BioCycLPNE272624:GHDI-1021-MONOMER.

Family and domain databases

Gene3D3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPMF_00703. Thymid_phosp_2.
InterProIPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view]
PANTHERPTHR10515. PTHR10515. 1 hit.
PfamPF02885. Glycos_trans_3N. 1 hit.
PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view]
PIRSFPIRSF000478. TP_PyNP. 1 hit.
SMARTSM00941. PYNP_C. 1 hit.
[Graphical view]
SUPFAMSSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsTIGR02645. ARCH_P_rylase. 1 hit.
PROSITEPS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTYPH_LEGPH
AccessionPrimary (citable) accession number: Q5ZWR3
Entry history
Integrated into UniProtKB/Swiss-Prot: March 7, 2006
Last sequence update: November 23, 2004
Last modified: May 14, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families