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Protein
Submitted name:

Adenylate cyclase

Gene

cyaA4

Organism
Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. adenylate cyclase activity Source: UniProtKB-EC
  2. signal transducer activity Source: InterPro

GO - Biological processi

  1. intracellular signal transduction Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseImported

Enzyme and pathway databases

BioCyciLPNE272624:GHDI-1129-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Adenylate cyclaseImported (EC:4.6.1.1Imported)
Gene namesi
Name:cyaA4Imported
Ordered Locus Names:lpg1130Imported
OrganismiLegionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)Imported
Taxonomic identifieri272624 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesLegionellaceaeLegionella
ProteomesiUP000000609 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi272624.lpg1130.

Structurei

3D structure databases

ProteinModelPortaliQ5ZWF5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG2114.
HOGENOMiHOG000278090.
KOiK01768.
OMAiTRFISHA.
OrthoDBiEOG6VQPPK.

Family and domain databases

Gene3Di3.30.70.1230. 1 hit.
InterProiIPR001054. A/G_cyclase.
IPR003660. HAMP_linker_domain.
IPR029787. Nucleotide_cyclase.
[Graphical view]
PfamiPF00211. Guanylate_cyc. 1 hit.
PF00672. HAMP. 1 hit.
[Graphical view]
SMARTiSM00044. CYCc. 1 hit.
SM00304. HAMP. 1 hit.
[Graphical view]
SUPFAMiSSF55073. SSF55073. 1 hit.
PROSITEiPS50125. GUANYLATE_CYCLASE_2. 1 hit.
PS50885. HAMP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5ZWF5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFRTKLFLG LLLIVITTNG IFLFLSYQYG KETVYKEVGS SALSIAAATA
60 70 80 90 100
VLMNPEDIQK FNLDTSANSP LYKDLEKKLL EVRNANRRKD VYVNFIYSLF
110 120 130 140 150
PDSNNPKVLR FAVDPEENTI DKTELGTVMK LKTESGQTIN VNYESPIVLP
160 170 180 190 200
EFVEDIWGTW LTALYPIKDA QGKYLGNIRV DVDADSVNQR FHFLLYSGIA
210 220 230 240 250
VFISTFLFAI FLGWLLFQWF NKPLLKITTA LKNIAQGDLE QHLDIRTKDE
260 270 280 290 300
FAEVGRVINE MTEGLRQRNM LQVSLTRFIS HALAEKIVKS GELPQVFSER
310 320 330 340 350
RKVTIMVCDI RDFTTISERI KPELVVDFLN HFFEKMIEAI TSQHGILDKY
360 370 380 390 400
LGDGFLAIFG SPDDDAYQED HAIHAALKMR EAMKSLNADW AKILGSEIQI
410 420 430 440 450
GIGINTGSAI VGNIGTDIHM EYTAIGDTVN LASRIENATK KLNTDILISE
460 470 480
YTYIATDHTA FQFIELGEIS IKGRVHKVKV YTL
Length:483
Mass (Da):54,667
Last modified:November 23, 2004 - v1
Checksum:i4B44C0DFF3ABD4B3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017354 Genomic DNA. Translation: AAU27216.1.
RefSeqiYP_095163.1. NC_002942.5.

Genome annotation databases

EnsemblBacteriaiAAU27216; AAU27216; lpg1130.
GeneIDi19832695.
KEGGilpn:lpg1130.
PATRICi22329322. VBILegPne29832_1187.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017354 Genomic DNA. Translation: AAU27216.1.
RefSeqiYP_095163.1. NC_002942.5.

3D structure databases

ProteinModelPortaliQ5ZWF5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272624.lpg1130.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAU27216; AAU27216; lpg1130.
GeneIDi19832695.
KEGGilpn:lpg1130.
PATRICi22329322. VBILegPne29832_1187.

Phylogenomic databases

eggNOGiCOG2114.
HOGENOMiHOG000278090.
KOiK01768.
OMAiTRFISHA.
OrthoDBiEOG6VQPPK.

Enzyme and pathway databases

BioCyciLPNE272624:GHDI-1129-MONOMER.

Family and domain databases

Gene3Di3.30.70.1230. 1 hit.
InterProiIPR001054. A/G_cyclase.
IPR003660. HAMP_linker_domain.
IPR029787. Nucleotide_cyclase.
[Graphical view]
PfamiPF00211. Guanylate_cyc. 1 hit.
PF00672. HAMP. 1 hit.
[Graphical view]
SMARTiSM00044. CYCc. 1 hit.
SM00304. HAMP. 1 hit.
[Graphical view]
SUPFAMiSSF55073. SSF55073. 1 hit.
PROSITEiPS50125. GUANYLATE_CYCLASE_2. 1 hit.
PS50885. HAMP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Philadelphia 1 / ATCC 33152 / DSM 7513Imported.

Entry informationi

Entry nameiQ5ZWF5_LEGPH
AccessioniPrimary (citable) accession number: Q5ZWF5
Entry historyi
Integrated into UniProtKB/TrEMBL: November 23, 2004
Last sequence update: November 23, 2004
Last modified: February 4, 2015
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.