Q5ZUC1 (ACYP_LEGPH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acylphosphatase
EC=3.6.1.7

Alternative name(s):
Acylphosphate phosphohydrolase

Gene names

Name:	acyP
Ordered Locus Names:	lpg1886

Organism

Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513) [Complete proteome] [HAMAP]

Taxonomic identifier

272624 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Legionellales › Legionellaceae › Legionella

Protein attributes

Sequence length	91 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	An acylphosphate + H2O = a carboxylate + phosphate. HAMAP MF_01450
Sequence similarities	Belongs to the acylphosphatase family. Contains 1 acylphosphatase-like domain.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	acylphosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 91	91	Acylphosphatase HAMAP MF_01450		PRO_0000326735
Regions
	Domain	6 – 91	86	Acylphosphatase-like
Sites
	Active site	21	1	By similarity
	Active site	39	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q5ZUC1 [UniParc]. Last modified November 23, 2004. Version 1. Checksum: B3C1F5BAC726F48A	FASTA	91	10,568
	10 20 30 40 50 60 MTKELCMRCY ISGRVQGVWF RASAKNLAEQ LMISGWARNL ADGRVEVFAC GKEDKLEEFY 70 80 90 TWLQKGPLNA RVDVCTRENL PWEDYISFDV L

References

[1]

"The genomic sequence of the accidental pathogen Legionella pneumophila." Chien M., Morozova I., Shi S., Sheng H., Chen J., Gomez S.M., Asamani G., Hill K., Nuara J., Feder M., Rineer J., Greenberg J.J., Steshenko V., Park S.H., Zhao B., Teplitskaya E., Edwards J.R., Pampou S. , Georghiou A., Chou I.-C., Iannuccilli W., Ulz M.E., Kim D.H., Geringer-Sameth A., Goldsberry C., Morozov P., Fischer S.G., Segal G., Qu X., Rzhetsky A., Zhang P., Cayanis E., De Jong P.J., Ju J., Kalachikov S., Shuman H.A., Russo J.J. Science 305:1966-1968(2004) [PubMed: 15448271] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Philadelphia 1 / ATCC 33152 / DSM 7513.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017354 Genomic DNA. Translation: AAU27956.1.
RefSeq	YP_095903.1. NC_002942.5.
3D structure databases
HSSP	HSSP built from PDB template 1W2I based on UniProtKB P84142.
ProteinModelPortal	Q5ZUC1.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5ZUC1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3078351.
GenomeReviews	Gene locus lpg1886 in contig AE017354_GR.
KEGG	lpn:lpg1886.
NMPDR	fig|272624.3.peg.715.
PATRIC	22330914. VBILegPne29832_1969.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1254.
HOGENOM	HBG750266.
OMA	WFRASAK.
PhylomeDB	Q5ZUC1.
ProtClustDB	PRK14451.
Enzyme and pathway databases
BioCyc	LPNE272624:LPG1886-MONOMER.
Family and domain databases
HAMAP	MF_01450. Acylphosphatase. [Tree]
InterPro	IPR001792. Acylphosphatase-like. IPR017968. Acylphosphatase_CS. [Graphical view]
KO	K01512.
Pfam	PF00708. Acylphosphatase. 1 hit. [Graphical view]
SUPFAM	SSF54975. Acylphosphatase. 1 hit.
PROSITE	PS00150. ACYLPHOSPHATASE_1. 1 hit. PS00151. ACYLPHOSPHATASE_2. 1 hit. PS51160. ACYLPHOSPHATASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACYP_LEGPH

Accession

Primary (citable) accession number: Q5ZUC1

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
Last sequence update:	November 23, 2004
Last modified:	January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program