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Protein
Submitted name:

Ectonucleoside triphosphate diphosphohydrolase I

Gene

lpg1905

Organism
Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei80AMPCombined sources1
Binding sitei118ATP analogCombined sources1
Metal bindingi140Magnesium; via carbonyl oxygenCombined sources1
Metal bindingi143Magnesium; via carbonyl oxygenCombined sources1
Metal bindingi146Magnesium; via carbonyl oxygenCombined sources1
Binding sitei159ATP analogCombined sources1
Binding sitei189AMP; via amide nitrogenCombined sources1
Binding sitei231AMPCombined sources1
Binding sitei302AMPCombined sources1
Binding sitei346AMPCombined sources1
Binding sitei346ATP analogCombined sources1
Binding sitei350AMPCombined sources1
Binding sitei350ATP analogCombined sources1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi52 – 56AMPCombined sources5
Nucleotide bindingi52 – 56ATP analogCombined sources5
Nucleotide bindingi189 – 191ATP analogCombined sources3
Nucleotide bindingi231 – 232ATP analogCombined sources2
Nucleotide bindingi299 – 302ATP analogCombined sources4

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseImported

Keywords - Ligandi

MagnesiumCombined sources, Metal-bindingCombined sources, Nucleotide-bindingCombined sources

Names & Taxonomyi

Protein namesi
Submitted name:
Ectonucleoside triphosphate diphosphohydrolase IImported
Gene namesi
Ordered Locus Names:lpg1905Imported
OrganismiLegionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)Imported
Taxonomic identifieri272624 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesLegionellaceaeLegionella
Proteomesi
  • UP000000609 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi39 ↔ 44Combined sources
Disulfide bondi244 ↔ 264Combined sources
Disulfide bondi330 ↔ 351Combined sources

Proteomic databases

PaxDbiQ5ZUA2.

Interactioni

Protein-protein interaction databases

STRINGi272624.lpg1905.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3AAPX-ray1.60A41-393[»]
3AAQX-ray2.00A41-393[»]
3AARX-ray1.65A41-393[»]
4BR4X-ray1.45A37-393[»]
4BR7X-ray1.80A37-393[»]
4BR9X-ray1.40A/B35-393[»]
4BRAX-ray1.60A/B35-393[»]
4BRCX-ray1.30A/B35-393[»]
4BRDX-ray1.50A/B35-393[»]
4BREX-ray1.60A/B35-393[»]
4BRFX-ray1.60A/B35-393[»]
4BRGX-ray1.45A/B35-393[»]
4BRHX-ray1.69A/B35-393[»]
4BRIX-ray1.75A/B35-393[»]
4BRKX-ray1.50A/B35-393[»]
4BRLX-ray1.60A/B35-393[»]
4BRMX-ray2.02A/B35-393[»]
4BRNX-ray1.69A/B35-393[»]
4BROX-ray1.99A/B35-393[»]
4BRPX-ray2.50A/B/C/D35-393[»]
4BRQX-ray1.45A/B35-393[»]
4BVOX-ray1.70A37-393[»]
4BVPX-ray1.49A/B35-393[»]
ProteinModelPortaliQ5ZUA2.
SMRiQ5ZUA2.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ5ZUA2.

Family & Domainsi

Phylogenomic databases

eggNOGiENOG41060TY. Bacteria.
COG5371. LUCA.
HOGENOMiHOG000278356.
OMAiFRVLIFL.

Family and domain databases

InterProiIPR000407. GDA1_CD39_NTPase.
[Graphical view]
PANTHERiPTHR11782. PTHR11782. 1 hit.
PfamiPF01150. GDA1_CD39. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5ZUA2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYHSKTSILA LYQLMFRVLI FLSCLVILTP NTIADTNPCE KHSCIAVIDA
60 70 80 90 100
GSTGSRLHIY SYDTDDTNTP IHIEEIWNKK IKPGFASIQP NSVTIDAYLT
110 120 130 140 150
MLLADAPIHN IPVYFYATAG MRLLPQSQQK KYYDELEYWF RQQSQWQLAE
160 170 180 190 200
AKTITGNDEA LFDWLAVNYK LDTLKSVQNK SVGVMDMGGA SVQIVFPMPK
210 220 230 240 250
NAEISKHNQV ELNIYGQNIN LYVHSFLGLG QTEMSHQFLN SPSCFANDYP
260 270 280 290 300
LPDGESGQGN APSCKEEVTS LMNSVHKVNQ QIQPLLALNP VNEWYSIGGI
310 320 330 340 350
SNLASSQLFH FENSELTNQS LLQQGDNQIC HQQWDILNGQ YPDDEYLYQY
360 370 380 390
CLLSSYYYAL MVDGYGINPN QTIHYIPPEQ NLDWTIGVVL HRA
Length:393
Mass (Da):44,531
Last modified:November 23, 2004 - v1
Checksum:i71635FBA5EA6E876
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017354 Genomic DNA. Translation: AAU27975.1.
RefSeqiWP_010947622.1. NC_002942.5.
YP_095922.1. NC_002942.5.

Genome annotation databases

EnsemblBacteriaiAAU27975; AAU27975; lpg1905.
GeneIDi19833471.
KEGGilpn:lpg1905.
PATRICi22330956. VBILegPne29832_1990.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017354 Genomic DNA. Translation: AAU27975.1.
RefSeqiWP_010947622.1. NC_002942.5.
YP_095922.1. NC_002942.5.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3AAPX-ray1.60A41-393[»]
3AAQX-ray2.00A41-393[»]
3AARX-ray1.65A41-393[»]
4BR4X-ray1.45A37-393[»]
4BR7X-ray1.80A37-393[»]
4BR9X-ray1.40A/B35-393[»]
4BRAX-ray1.60A/B35-393[»]
4BRCX-ray1.30A/B35-393[»]
4BRDX-ray1.50A/B35-393[»]
4BREX-ray1.60A/B35-393[»]
4BRFX-ray1.60A/B35-393[»]
4BRGX-ray1.45A/B35-393[»]
4BRHX-ray1.69A/B35-393[»]
4BRIX-ray1.75A/B35-393[»]
4BRKX-ray1.50A/B35-393[»]
4BRLX-ray1.60A/B35-393[»]
4BRMX-ray2.02A/B35-393[»]
4BRNX-ray1.69A/B35-393[»]
4BROX-ray1.99A/B35-393[»]
4BRPX-ray2.50A/B/C/D35-393[»]
4BRQX-ray1.45A/B35-393[»]
4BVOX-ray1.70A37-393[»]
4BVPX-ray1.49A/B35-393[»]
ProteinModelPortaliQ5ZUA2.
SMRiQ5ZUA2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272624.lpg1905.

Proteomic databases

PaxDbiQ5ZUA2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAU27975; AAU27975; lpg1905.
GeneIDi19833471.
KEGGilpn:lpg1905.
PATRICi22330956. VBILegPne29832_1990.

Phylogenomic databases

eggNOGiENOG41060TY. Bacteria.
COG5371. LUCA.
HOGENOMiHOG000278356.
OMAiFRVLIFL.

Miscellaneous databases

EvolutionaryTraceiQ5ZUA2.

Family and domain databases

InterProiIPR000407. GDA1_CD39_NTPase.
[Graphical view]
PANTHERiPTHR11782. PTHR11782. 1 hit.
PfamiPF01150. GDA1_CD39. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5ZUA2_LEGPH
AccessioniPrimary (citable) accession number: Q5ZUA2
Entry historyi
Integrated into UniProtKB/TrEMBL: November 23, 2004
Last sequence update: November 23, 2004
Last modified: November 2, 2016
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.