Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q5ZUA2 (Q5ZUA2_LEGPH) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length393 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding52 – 565AMP PDB 4BRN
Region52 – 565Phosphate 1 binding
Region118 – 1192Phosphate 2 binding
Region189 – 1913Sulfate 1 binding PDB 4BRM PDB 4BR9
Region189 – 1902Sulfate 2 binding PDB 4BRM
Region190 – 1934Phosphate 2 binding
Region227 – 2282Sulfate 3 binding PDB 4BRM PDB 4BR9
Region227 – 2282Sulfate 4 binding PDB 4BRM PDB 4BR9
Region327 – 3282Chloride 9 binding PDB 4BR4 PDB 4BR7

Sites

Metal binding1401Magnesium; via carbonyl oxygen PDB 4BRN
Metal binding1401Sodium; via carbonyl oxygen PDB 4BVO
Metal binding1431Magnesium; via carbonyl oxygen PDB 4BRN
Metal binding1431Sodium; via carbonyl oxygen PDB 4BVO
Metal binding1461Magnesium; via carbonyl oxygen PDB 4BRN
Metal binding1461Sodium; via carbonyl oxygen PDB 4BVO
Binding site521Sulfate 1 PDB 4BRM PDB 4BR9
Binding site521Sulfate 2; via amide nitrogen PDB 4BRM
Binding site801AMP
Binding site891Chloride 1 PDB 4BRC PDB 4BRK PDB 4BRN
Binding site891Chloride 2; via amide nitrogen PDB 4BRK
Binding site1181Sulfate 1 PDB 4BRM PDB 4BR9
Binding site1221Chloride 6 PDB 4BRM
Binding site1561Chloride 4; via amide nitrogen PDB 4BR7
Binding site1561Chloride 5; via amide nitrogen PDB 4BRK PDB 4BVP
Binding site1591Phosphate 2
Binding site1891AMP; via amide nitrogen PDB 4BRN
Binding site1891Phosphate 1; via amide nitrogen
Binding site2311AMP PDB 4BRN
Binding site2401Sulfate 1 PDB 4BR9
Binding site2401Sulfate 5 PDB 4BRM PDB 4BR9
Binding site2531Chloride 7 (covalent) PDB 4BRH PDB 4BRK PDB 4BRM
Binding site2761Sulfate 3 PDB 4BRM PDB 4BR9
Binding site2761Sulfate 4 PDB 4BR9
Binding site3021AMP PDB 4BRN
Binding site3461AMP PDB 4BRN
Binding site3501AMP

Sequences

Sequence LengthMass (Da)Tools
Q5ZUA2 [UniParc].

Last modified November 23, 2004. Version 1.
Checksum: 71635FBA5EA6E876

FASTA39344,531
        10         20         30         40         50         60 
MYHSKTSILA LYQLMFRVLI FLSCLVILTP NTIADTNPCE KHSCIAVIDA GSTGSRLHIY 

        70         80         90        100        110        120 
SYDTDDTNTP IHIEEIWNKK IKPGFASIQP NSVTIDAYLT MLLADAPIHN IPVYFYATAG 

       130        140        150        160        170        180 
MRLLPQSQQK KYYDELEYWF RQQSQWQLAE AKTITGNDEA LFDWLAVNYK LDTLKSVQNK 

       190        200        210        220        230        240 
SVGVMDMGGA SVQIVFPMPK NAEISKHNQV ELNIYGQNIN LYVHSFLGLG QTEMSHQFLN 

       250        260        270        280        290        300 
SPSCFANDYP LPDGESGQGN APSCKEEVTS LMNSVHKVNQ QIQPLLALNP VNEWYSIGGI 

       310        320        330        340        350        360 
SNLASSQLFH FENSELTNQS LLQQGDNQIC HQQWDILNGQ YPDDEYLYQY CLLSSYYYAL 

       370        380        390 
MVDGYGINPN QTIHYIPPEQ NLDWTIGVVL HRA 

« Hide

References

« Hide 'large scale' references
[1]"The genomic sequence of the accidental pathogen Legionella pneumophila."
Chien M., Morozova I., Shi S., Sheng H., Chen J., Gomez S.M., Asamani G., Hill K., Nuara J., Feder M., Rineer J., Greenberg J.J., Steshenko V., Park S.H., Zhao B., Teplitskaya E., Edwards J.R., Pampou S. expand/collapse author list , Georghiou A., Chou I.C., Iannuccilli W., Ulz M.E., Kim D.H., Geringer-Sameth A., Goldsberry C., Morozov P., Fischer S.G., Segal G., Qu X., Rzhetsky A., Zhang P., Cayanis E., De Jong P.J., Ju J., Kalachikov S., Shuman H.A., Russo J.J.
Science 305:1966-1968(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Philadelphia 1 / ATCC 33152 / DSM 7513.
[2]"Crystal structure of a Legionella pneumophila ecto -triphosphate diphosphohydrolase, a structural and functional homolog of the eukaryotic NTPDases."
Vivian J.P., Riedmaier P., Ge H., Le Nours J., Sansom F.M., Wilce M.C., Byres E., Dias M., Schmidberger J.W., Cowan P.J., d'Apice A.J., Hartland E.L., Rossjohn J., Beddoe T.
Structure 18:228-238(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.60 ANGSTROMS) OF 41-393.
[3]"Crystallographic snapshots along the reaction pathway of nucleoside triphosphate diphosphohydrolases."
Zebisch M., Krauss M., Schafer P., Lauble P., Strater N.
Structure 21:1460-1475(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.30 ANGSTROMS) OF 35-393 IN COMPLEX WITH AMP; CHLORIDE; MAGNESIUM; PHOSPHATE AND SULFATE.
[4]"Structures of Legionella pneumophila NTPDase1 in complex with polyoxometallates."
Zebisch M., Krauss M., Schafer P., Strater N.
Acta Crystallogr. D 70:1147-1154(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.49 ANGSTROMS) OF 35-393 IN COMPLEX WITH CHLORIDE AND SODIUM.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017354 Genomic DNA. Translation: AAU27975.1.
RefSeqYP_095922.1. NC_002942.5.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3AAPX-ray1.60A41-393[»]
3AAQX-ray2.00A41-393[»]
3AARX-ray1.65A41-393[»]
4BR4X-ray1.45A37-393[»]
4BR7X-ray1.80A37-393[»]
4BR9X-ray1.40A/B35-393[»]
4BRAX-ray1.60A/B35-393[»]
4BRCX-ray1.30A/B35-393[»]
4BRDX-ray1.50A/B35-393[»]
4BREX-ray1.60A/B35-393[»]
4BRFX-ray1.60A/B35-393[»]
4BRGX-ray1.45A/B35-393[»]
4BRHX-ray1.69A/B35-393[»]
4BRIX-ray1.75A/B35-393[»]
4BRKX-ray1.50A/B35-393[»]
4BRLX-ray1.60A/B35-393[»]
4BRMX-ray2.02A/B35-393[»]
4BRNX-ray1.69A/B35-393[»]
4BROX-ray1.99A/B35-393[»]
4BRPX-ray2.50A/B/C/D35-393[»]
4BRQX-ray1.45A/B35-393[»]
4BVOX-ray1.70A37-393[»]
4BVPX-ray1.49A/B35-393[»]
ProteinModelPortalQ5ZUA2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272624.lpg1905.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAU27975; AAU27975; lpg1905.
GeneID3078951.
KEGGlpn:lpg1905.
PATRIC22330956. VBILegPne29832_1990.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG5371.
HOGENOMHOG000278356.
OMAFANDYPL.
OrthoDBEOG63Z74J.

Enzyme and pathway databases

BioCycLPNE272624:GHDI-1904-MONOMER.

Family and domain databases

InterProIPR000407. GDA1_CD39_NTPase.
[Graphical view]
PANTHERPTHR11782. PTHR11782. 1 hit.
PfamPF01150. GDA1_CD39. 2 hits.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ5ZUA2.

Entry information

Entry nameQ5ZUA2_LEGPH
AccessionPrimary (citable) accession number: Q5ZUA2
Entry history
Integrated into UniProtKB/TrEMBL: November 23, 2004
Last sequence update: November 23, 2004
Last modified: June 11, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)