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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:lpg2031
OrganismiLegionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)
Taxonomic identifieri272624 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesLegionellaceaeLegionella
Proteomesi
  • UP000000609 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002420391 – 589Arginine--tRNA ligaseAdd BLAST589

Proteomic databases

PaxDbiQ5ZTX7

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi272624.lpg2031

Structurei

3D structure databases

ProteinModelPortaliQ5ZTX7
SMRiQ5ZTX7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi131 – 141"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247214
KOiK01887
OMAiNKPLHLG

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.701 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 2 hits
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q5ZTX7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRSMKAIIEY LLKQALINLQ QSGEMPIDLE IEIKVENAKD PAHGDYATNL
60 70 80 90 100
ALVLAKPCRQ APKVLAERLV AVIPVDPSVE KIEIAGAGFI NFFMRSTARS
110 120 130 140 150
LIISEILNKG KEFGRGNLGQ SQKVLIEFVS ANPTGPLHVG HGRGAAFGAT
160 170 180 190 200
LGNVLKAAGY DVTLEYYVND AGRQMNILAV SVWLRYLELA GEPIVFPANG
210 220 230 240 250
YKGQYVYEIA QEIWSEQGNQ FVHPWISVVE NLPADEPEGG DKETYIDAII
260 270 280 290 300
ARAQSLLGKD GFANFHQHAL KTVLDDIKDD LQAFGVRFDS WFSEQSLFED
310 320 330 340 350
GSIEKGIQAL KDRGHTYERE GALWFRATDF GDEKDRVLVR ANGQTTYFAS
360 370 380 390 400
DVAYHWNKYD RGFDRVIDIF GADHHGYVTR IKTAVKALGH DESALDVILV
410 420 430 440 450
QFAILYRGGD RVQMSTRSGS FVTLRELREE VGNDAARYFY VARKPEQHMD
460 470 480 490 500
FDLDLAKSES SDNPVYYIQY AHARICSVLR QLKERGLKWD KDMGLKNLDL
510 520 530 540 550
LEQQHEATLI SLIARYPEVI QSAAASCEPH QLAYYLRELA NGLHSYYNAI
560 570 580
QLLCEQEQLR CARLCLLESV RQVLNNGLAI LGVSAPESM
Length:589
Mass (Da):66,030
Last modified:November 23, 2004 - v1
Checksum:i86910D393DCFD116
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017354 Genomic DNA Translation: AAU28100.1
RefSeqiWP_010947747.1, NC_002942.5
YP_096047.1, NC_002942.5

Genome annotation databases

EnsemblBacteriaiAAU28100; AAU28100; lpg2031
GeneIDi19833597
KEGGilpn:lpg2031
PATRICifig|272624.6.peg.2127

Similar proteinsi

Entry informationi

Entry nameiSYR_LEGPH
AccessioniPrimary (citable) accession number: Q5ZTX7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: November 23, 2004
Last modified: February 28, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome