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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei141GTPUniRule annotation1
Binding sitei145GTPUniRule annotation1
Binding sitei189GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi23 – 27GTPUniRule annotation5
Nucleotide bindingi110 – 112GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotationImported
Ordered Locus Names:lpg2609Imported
OrganismiLegionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)Imported
Taxonomic identifieri272624 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesLegionellaceaeLegionella
Proteomesi
  • UP000000609 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

PTM / Processingi

Proteomic databases

PaxDbiQ5ZSB0

Interactioni

Protein-protein interaction databases

STRINGi272624.lpg2609

Structurei

3D structure databases

ProteinModelPortaliQ5ZSB0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 207TubulinInterPro annotationAdd BLAST193
Domaini209 – 327Tubulin_CInterPro annotationAdd BLAST119

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDK Bacteria
COG0206 LUCA
HOGENOMiHOG000049094
KOiK03531
OMAiMRAVKGI

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.30.1330.20, 1 hit
3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR037103 Tubulin/FtsZ_C_sf
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q5ZSB0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFELMESSQQ ENNAVIKVVG VGGGGGNAVE HMVAENIDGV EFICANTDAQ
60 70 80 90 100
ALRGSSAKIH IQLGDALTKG LGAGANPQIG REAAEEDREH IKEILSGADM
110 120 130 140 150
VFITAGMGGG TGTGAAPVFA EIAKELGILT VAVVTKPFSF EGKQRALAAE
160 170 180 190 200
EGIRRLAEHV DSLITIPNNK LLSVLGKNIS LLNAFKAANN VLLGAVKGIS
210 220 230 240 250
DLITRPGLIN VDFADVRTVM SEMGMAMMGT GSAVGEQRAR QAAEAAIASP
260 270 280 290 300
LLEDVNFSGA RGILVNITAG LDMSIGEFEE VGDVVKEFIS DDATVVVGTV
310 320 330 340 350
IDPEMTDEMR VTVIVTGLGD NRQRQQQPQQ PLRARLVETT RSDGSLDYQQ
360 370 380 390
LERPAVIRKQ AQTGTATTAT KQTNNGNESV PDVDYLDIPA FLRRQEEA
Length:398
Mass (Da):42,082
Last modified:November 23, 2004 - v1
Checksum:iCC4A0125D964F45D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017354 Genomic DNA Translation: AAU28667.1
RefSeqiWP_010948309.1, NC_002942.5
YP_096614.1, NC_002942.5

Genome annotation databases

EnsemblBacteriaiAAU28667; AAU28667; lpg2609
GeneIDi19834174
KEGGilpn:lpg2609
PATRICifig|272624.6.peg.2783

Similar proteinsi

Entry informationi

Entry nameiQ5ZSB0_LEGPH
AccessioniPrimary (citable) accession number: Q5ZSB0
Entry historyiIntegrated into UniProtKB/TrEMBL: November 23, 2004
Last sequence update: November 23, 2004
Last modified: March 28, 2018
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health