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Protein
Submitted name:

Valosin containing protein

Gene

VCP

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-GGA-110320. Translesion Synthesis by POLH.
R-GGA-382556. ABC-family proteins mediated transport.
R-GGA-532668. N-glycan trimming in the ER and Calnexin/Calreticulin cycle.
R-GGA-5358346. Hedgehog ligand biogenesis.
R-GGA-5689877. Josephin domain DUBs.
R-GGA-5689896. Ovarian tumor domain proteases.
R-GGA-6798695. Neutrophil degranulation.
R-GGA-8876725. Protein methylation.

Names & Taxonomyi

Protein namesi
Submitted name:
Valosin containing proteinImported
Gene namesi
Name:VCPImported
Synonyms:vcpImported
ORF Names:RCJMB04_1c3Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome Z

Expressioni

Gene expression databases

BgeeiENSGALG00000001986.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
KCNMA1Q8AYS83EBI-1637127,EBI-1635766

Protein-protein interaction databases

IntActiQ5ZMU9. 1 interactor.
STRINGi9031.ENSGALP00000003089.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 108CDC48_NInterPro annotationAdd BLAST84
Domaini125 – 191CDC48_2InterPro annotationAdd BLAST67
Domaini237 – 373AAAInterPro annotationAdd BLAST137
Domaini510 – 649AAAInterPro annotationAdd BLAST140

Sequence similaritiesi

Belongs to the AAA ATPase family.SAAS annotation

Phylogenomic databases

eggNOGiKOG0730. Eukaryota.
COG0464. LUCA.
GeneTreeiENSGT00860000133780.
HOGENOMiHOG000223224.
HOVERGENiHBG001226.
KOiK13525.
OMAiMADSKGD.
OrthoDBiEOG091G024K.
TreeFamiTF300542.

Family and domain databases

Gene3Di3.10.330.10. 1 hit.
InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR005938. AAA_ATPase_CDC48.
IPR009010. Asp_de-COase-like_dom.
IPR003959. ATPase_AAA_core.
IPR003960. ATPase_AAA_CS.
IPR004201. Cdc48_dom2.
IPR029067. CDC48_domain_2-like.
IPR003338. CDC4_N-term_subdom.
IPR027417. P-loop_NTPase.
IPR015415. Vps4_C.
PfamiView protein in Pfam
PF00004. AAA. 2 hits.
PF02933. CDC48_2. 1 hit.
PF02359. CDC48_N. 1 hit.
PF09336. Vps4_C. 1 hit.
SMARTiView protein in SMART
SM00382. AAA. 2 hits.
SM01072. CDC48_2. 1 hit.
SM01073. CDC48_N. 1 hit.
SUPFAMiSSF50692. SSF50692. 1 hit.
SSF52540. SSF52540. 2 hits.
SSF54585. SSF54585. 1 hit.
TIGRFAMsiTIGR01243. CDC48. 1 hit.
PROSITEiView protein in PROSITE
PS00674. AAA. 2 hits.

Sequencei

Sequence statusi: Complete.

Q5ZMU9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASGSDSKAD DLSTAILKQK NRPNRLIVDE AINEDNSVVS LSQAKMDELQ
60 70 80 90 100
LFRGDTVLLK GKKRREAVCI VLSDDTCSDE KIRMNRVVRN NLRVRLGDVI
110 120 130 140 150
SIQPCPDVKY GKRIHVLPID DTVEGITGNL FEVYLKPYFL EAYRPIRKGD
160 170 180 190 200
IFLVRGGMRA VEFKVVETDP SPYCIVAPDT VIHCEGEPIK REDEEESLNE
210 220 230 240 250
VGYDDIGGCR KQLAQIKEMV ELPLRHPALF KAIGVKPPRG ILLYGPPGTG
260 270 280 290 300
KTLIARAVAN ETGAFFFLIN GPEIMSKLAG ESESNLRKAF EEAEKNAPAI
310 320 330 340 350
IFIDELDAIA PKREKTHGEV ERRIVSQLLT LMDGLKQRAH VIVMAATNRP
360 370 380 390 400
NSIDPALRRF GRFDREVDIG IPDATGRLEI LQIHTKNMKL ADDVDLEQVA
410 420 430 440 450
NETHGHVGAD LAALCSEAAL QAIRKKMDLI DLEDETIDAE VMNSLAVTMD
460 470 480 490 500
DFRWALSQSN PSALRETVVE VPQVTWEDIG GLEDVKRELQ ELVQYPVEHP
510 520 530 540 550
DKFLKFGMTP SKGVLFYGPP GCGKTLLAKA IANECQANFI SIKGPELLTM
560 570 580 590 600
WFGESEANVR EIFDKARQAA PCVLFFDELD SIAKARGGNI GDGGGAADRV
610 620 630 640 650
INQILTEMDG MSTKKNVFII GATNRPDIID PAILRPGRLD QLIYIPLPDE
660 670 680 690 700
KSRVAILKAN LRKSPVAKDV DLDFLAKMTN GFSGADLTEI CQRACKLAIR
710 720 730 740 750
ESIESEIRRE RERQTNPSAM EVEEDDPVPE IRRDHFEEAM RFARRSVSDN
760 770 780 790 800
DIRKYEMFAQ TLQQSRGFGS FRFPSGNQGG AGPSQGTGGG SGGNVYSEDN

DDDLYG
Length:806
Mass (Da):89,325
Last modified:November 23, 2004 - v1
Checksum:i5FBF0536FC0D17D3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC192464 Genomic DNA. No translation available.
AB195711 mRNA. Translation: BAE92937.1.
AJ719285 mRNA. Translation: CAG30944.1.
RefSeqiNP_001038129.1. NM_001044664.1.
UniGeneiGga.10045.

Genome annotation databases

EnsembliENSGALT00000003093; ENSGALP00000003089; ENSGALG00000001986.
GeneIDi427410.
KEGGigga:427410.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC192464 Genomic DNA. No translation available.
AB195711 mRNA. Translation: BAE92937.1.
AJ719285 mRNA. Translation: CAG30944.1.
RefSeqiNP_001038129.1. NM_001044664.1.
UniGeneiGga.10045.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ5ZMU9. 1 interactor.
STRINGi9031.ENSGALP00000003089.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSGALT00000003093; ENSGALP00000003089; ENSGALG00000001986.
GeneIDi427410.
KEGGigga:427410.

Organism-specific databases

CTDi7415.

Phylogenomic databases

eggNOGiKOG0730. Eukaryota.
COG0464. LUCA.
GeneTreeiENSGT00860000133780.
HOGENOMiHOG000223224.
HOVERGENiHBG001226.
KOiK13525.
OMAiMADSKGD.
OrthoDBiEOG091G024K.
TreeFamiTF300542.

Enzyme and pathway databases

ReactomeiR-GGA-110320. Translesion Synthesis by POLH.
R-GGA-382556. ABC-family proteins mediated transport.
R-GGA-532668. N-glycan trimming in the ER and Calnexin/Calreticulin cycle.
R-GGA-5358346. Hedgehog ligand biogenesis.
R-GGA-5689877. Josephin domain DUBs.
R-GGA-5689896. Ovarian tumor domain proteases.
R-GGA-6798695. Neutrophil degranulation.
R-GGA-8876725. Protein methylation.

Miscellaneous databases

PROiPR:Q5ZMU9.

Gene expression databases

BgeeiENSGALG00000001986.

Family and domain databases

Gene3Di3.10.330.10. 1 hit.
InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR005938. AAA_ATPase_CDC48.
IPR009010. Asp_de-COase-like_dom.
IPR003959. ATPase_AAA_core.
IPR003960. ATPase_AAA_CS.
IPR004201. Cdc48_dom2.
IPR029067. CDC48_domain_2-like.
IPR003338. CDC4_N-term_subdom.
IPR027417. P-loop_NTPase.
IPR015415. Vps4_C.
PfamiView protein in Pfam
PF00004. AAA. 2 hits.
PF02933. CDC48_2. 1 hit.
PF02359. CDC48_N. 1 hit.
PF09336. Vps4_C. 1 hit.
SMARTiView protein in SMART
SM00382. AAA. 2 hits.
SM01072. CDC48_2. 1 hit.
SM01073. CDC48_N. 1 hit.
SUPFAMiSSF50692. SSF50692. 1 hit.
SSF52540. SSF52540. 2 hits.
SSF54585. SSF54585. 1 hit.
TIGRFAMsiTIGR01243. CDC48. 1 hit.
PROSITEiView protein in PROSITE
PS00674. AAA. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiQ5ZMU9_CHICK
AccessioniPrimary (citable) accession number: Q5ZMU9
Secondary accession number(s): F1P4V8
Entry historyiIntegrated into UniProtKB/TrEMBL: November 23, 2004
Last sequence update: November 23, 2004
Last modified: May 10, 2017
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.