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Protein

Uncharacterized aarF domain-containing protein kinase 1

Gene

ADCK1

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr).

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei173ATPPROSITE-ProRule annotation1
Active sitei305Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi151 – 159ATPPROSITE-ProRule annotation9

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized aarF domain-containing protein kinase 1 (EC:2.7.11.-)
Gene namesi
Name:ADCK1
ORF Names:RCJMB04_1d9
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Unplaced

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_000025225118 – 519Uncharacterized aarF domain-containing protein kinase 1Add BLAST502

Proteomic databases

PaxDbiQ5ZMT7.
PRIDEiQ5ZMT7.

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000017088.

Structurei

3D structure databases

ProteinModelPortaliQ5ZMT7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini145 – 481Protein kinasePROSITE-ProRule annotationAdd BLAST337

Sequence similaritiesi

Contains 1 protein kinase domain.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG1235. Eukaryota.
COG0661. LUCA.
HOGENOMiHOG000240338.
HOVERGENiHBG056527.
InParanoidiQ5ZMT7.
KOiK08869.
PhylomeDBiQ5ZMT7.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR004147. UbiB_dom.
[Graphical view]
PfamiPF03109. ABC1. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 2 hits.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5ZMT7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARRALKLAS LAAAASGIYL YGNKFMDPND FGVVRVGRAI ATTAVITYDY
60 70 80 90 100
LTSLRNVPYG SEEYDFLKSQ VHLRSAERLR ELCCANRGTF IKVGQHLGAL
110 120 130 140 150
DYLLPEEYTR TLKVLHSQAP QSTRQEIEQV IREDLGKEIK ELFVSFEDTP
160 170 180 190 200
LGAASLAQVH KAVLQDGRTV AVKIQHPKVQ AQSSKDIFLM EVLLLVVKQI
210 220 230 240 250
FPDFEFMWLV EEAKKNLPLE LDFLNEGRNA EKVAQMLKNF EFLKVPRIYW
260 270 280 290 300
ELSTRRVLLM EFMEGGQVND KAYMEKNGID VNEISRNLGK LYSEMIFVNG
310 320 330 340 350
FVHCDPHPGN VLVKKCPDSG KAYIILLDHG LYQVLSESFR MDYCRLWLAL
360 370 380 390 400
IKADMKRVQK YSRRLGAGDL YPLFACMLTA RSWESVNRGI DQSPVSASED
410 420 430 440 450
VEIRSNAAAY LPQITQLLNN VPRQMLLLLK TNDLLRGIES ALHTRASASS
460 470 480 490 500
FLNMSRCCIR AVSTYQRSKS HSLYRRVHIS LTEALSLWQI NLYELFLWLK
510
GSRLGSWVIA FLSRMHHST
Length:519
Mass (Da):59,201
Last modified:November 23, 2004 - v1
Checksum:iB770875CB6592577
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ719297 mRNA. Translation: CAG30956.1.
RefSeqiNP_001073199.1. NM_001079731.1.
UniGeneiGga.9041.

Genome annotation databases

GeneIDi423382.
KEGGigga:423382.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ719297 mRNA. Translation: CAG30956.1.
RefSeqiNP_001073199.1. NM_001079731.1.
UniGeneiGga.9041.

3D structure databases

ProteinModelPortaliQ5ZMT7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000017088.

Proteomic databases

PaxDbiQ5ZMT7.
PRIDEiQ5ZMT7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi423382.
KEGGigga:423382.

Organism-specific databases

CTDi57143.

Phylogenomic databases

eggNOGiKOG1235. Eukaryota.
COG0661. LUCA.
HOGENOMiHOG000240338.
HOVERGENiHBG056527.
InParanoidiQ5ZMT7.
KOiK08869.
PhylomeDBiQ5ZMT7.

Miscellaneous databases

PROiQ5ZMT7.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR004147. UbiB_dom.
[Graphical view]
PfamiPF03109. ABC1. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 2 hits.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiADCK1_CHICK
AccessioniPrimary (citable) accession number: Q5ZMT7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: November 23, 2004
Last modified: June 8, 2016
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.