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Q5ZMS2

- PA1B2_CHICK

UniProt

Q5ZMS2 - PA1B2_CHICK

Protein

Platelet-activating factor acetylhydrolase IB subunit beta

Gene

PAFAH1B2

Organism
Gallus gallus (Chicken)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (23 Nov 2004)
      Previous versions | rss
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    Functioni

    Inactivates PAF by removing the acetyl group at the sn-2 position.By similarity

    Catalytic activityi

    1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-alkyl-sn-glycero-3-phosphocholine + acetate.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei48 – 481By similarity
    Active sitei193 – 1931By similarity
    Active sitei196 – 1961By similarity

    GO - Molecular functioni

    1. 1-alkyl-2-acetylglycerophosphocholine esterase activity Source: UniProtKB-EC

    GO - Biological processi

    1. lipid catabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Lipid degradation, Lipid metabolism

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Platelet-activating factor acetylhydrolase IB subunit beta (EC:3.1.1.47)
    Alternative name(s):
    PAF acetylhydrolase 30 kDa subunit
    Short name:
    PAF-AH 30 kDa subunit
    PAF-AH subunit beta
    PAFAH subunit beta
    Gene namesi
    Name:PAFAH1B2
    Synonyms:PAFAHB
    ORF Names:RCJMB04_1f10
    OrganismiGallus gallus (Chicken)
    Taxonomic identifieri9031 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus
    ProteomesiUP000000539: Unplaced

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 229229Platelet-activating factor acetylhydrolase IB subunit betaPRO_0000252684Add
    BLAST

    Proteomic databases

    PaxDbiQ5ZMS2.

    Interactioni

    Protein-protein interaction databases

    STRINGi9031.ENSGALP00000011588.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5ZMS2.
    SMRiQ5ZMS2. Positions 6-223.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiNOG69837.
    HOGENOMiHOG000232143.
    HOVERGENiHBG053477.
    InParanoidiQ5ZMS2.
    PhylomeDBiQ5ZMS2.

    Family and domain databases

    Gene3Di3.40.50.1110. 1 hit.
    InterProiIPR013831. SGNH_hydro-type_esterase_dom.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5ZMS2-1 [UniParc]FASTAAdd to Basket

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    MSHGDSNPAA VPHAADDIQG DDRWMSQHNR FVSDCKDKEP DVLFVGDSMV    50
    QLLQQYEIWR ELFSPLHALN FWIGGDTTGH VLWRLKNGEL ENIKPKVIVV 100
    WVGTNNYGNT AEEVAGGIEA IVRLINTQQP QAKVIVLGLL PRGEKPNPLR 150
    QKNAKVNHLL KASLPKLPNV QLLDVDAGFV HSDGTISYHD MFDFLHLTGG 200
    AYAKICKPLH ELIMQLLEET PEEKRAALA 229
    Length:229
    Mass (Da):25,567
    Last modified:November 23, 2004 - v1
    Checksum:i27AEDEAA33C4B130
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ719312 mRNA. Translation: CAG30971.1.
    UniGeneiGga.17363.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ719312 mRNA. Translation: CAG30971.1 .
    UniGenei Gga.17363.

    3D structure databases

    ProteinModelPortali Q5ZMS2.
    SMRi Q5ZMS2. Positions 6-223.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9031.ENSGALP00000011588.

    Proteomic databases

    PaxDbi Q5ZMS2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    eggNOGi NOG69837.
    HOGENOMi HOG000232143.
    HOVERGENi HBG053477.
    InParanoidi Q5ZMS2.
    PhylomeDBi Q5ZMS2.

    Miscellaneous databases

    NextBioi 20822772.
    PROi Q5ZMS2.

    Family and domain databases

    Gene3Di 3.40.50.1110. 1 hit.
    InterProi IPR013831. SGNH_hydro-type_esterase_dom.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: CB.
      Tissue: Bursa of Fabricius.

    Entry informationi

    Entry nameiPA1B2_CHICK
    AccessioniPrimary (citable) accession number: Q5ZMS2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 17, 2006
    Last sequence update: November 23, 2004
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3