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Q5ZMS2

- PA1B2_CHICK

UniProt

Q5ZMS2 - PA1B2_CHICK

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Protein

Platelet-activating factor acetylhydrolase IB subunit beta

Gene
PAFAH1B2, PAFAHB, RCJMB04_1f10
Organism
Gallus gallus (Chicken)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Inactivates PAF by removing the acetyl group at the sn-2 position By similarity.

Catalytic activityi

1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-alkyl-sn-glycero-3-phosphocholine + acetate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei48 – 481 By similarity
Active sitei193 – 1931 By similarity
Active sitei196 – 1961 By similarity

GO - Molecular functioni

  1. 1-alkyl-2-acetylglycerophosphocholine esterase activity Source: UniProtKB-EC

GO - Biological processi

  1. lipid catabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Lipid degradation, Lipid metabolism

Names & Taxonomyi

Protein namesi
Recommended name:
Platelet-activating factor acetylhydrolase IB subunit beta (EC:3.1.1.47)
Alternative name(s):
PAF acetylhydrolase 30 kDa subunit
Short name:
PAF-AH 30 kDa subunit
PAF-AH subunit beta
PAFAH subunit beta
Gene namesi
Name:PAFAH1B2
Synonyms:PAFAHB
ORF Names:RCJMB04_1f10
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus
ProteomesiUP000000539: Unplaced

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 229229Platelet-activating factor acetylhydrolase IB subunit betaPRO_0000252684Add
BLAST

Proteomic databases

PaxDbiQ5ZMS2.

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000011588.

Structurei

3D structure databases

ProteinModelPortaliQ5ZMS2.
SMRiQ5ZMS2. Positions 6-223.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiNOG69837.
HOGENOMiHOG000232143.
HOVERGENiHBG053477.
InParanoidiQ5ZMS2.
PhylomeDBiQ5ZMS2.

Family and domain databases

Gene3Di3.40.50.1110. 1 hit.
InterProiIPR013831. SGNH_hydro-type_esterase_dom.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5ZMS2-1 [UniParc]FASTAAdd to Basket

« Hide

MSHGDSNPAA VPHAADDIQG DDRWMSQHNR FVSDCKDKEP DVLFVGDSMV    50
QLLQQYEIWR ELFSPLHALN FWIGGDTTGH VLWRLKNGEL ENIKPKVIVV 100
WVGTNNYGNT AEEVAGGIEA IVRLINTQQP QAKVIVLGLL PRGEKPNPLR 150
QKNAKVNHLL KASLPKLPNV QLLDVDAGFV HSDGTISYHD MFDFLHLTGG 200
AYAKICKPLH ELIMQLLEET PEEKRAALA 229
Length:229
Mass (Da):25,567
Last modified:November 23, 2004 - v1
Checksum:i27AEDEAA33C4B130
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ719312 mRNA. Translation: CAG30971.1.
UniGeneiGga.17363.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ719312 mRNA. Translation: CAG30971.1 .
UniGenei Gga.17363.

3D structure databases

ProteinModelPortali Q5ZMS2.
SMRi Q5ZMS2. Positions 6-223.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9031.ENSGALP00000011588.

Proteomic databases

PaxDbi Q5ZMS2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

eggNOGi NOG69837.
HOGENOMi HOG000232143.
HOVERGENi HBG053477.
InParanoidi Q5ZMS2.
PhylomeDBi Q5ZMS2.

Miscellaneous databases

NextBioi 20822772.
PROi Q5ZMS2.

Family and domain databases

Gene3Di 3.40.50.1110. 1 hit.
InterProi IPR013831. SGNH_hydro-type_esterase_dom.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: CB.
    Tissue: Bursa of Fabricius.

Entry informationi

Entry nameiPA1B2_CHICK
AccessioniPrimary (citable) accession number: Q5ZMS2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: November 23, 2004
Last modified: April 16, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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