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Protein

Exportin-4

Gene

XPO4

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Mediates the nuclear export of proteins (cargos) with broad substrate specificity.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Exportin-4
Gene namesi
Name:XPO4
ORF Names:RCJMB04_1f17
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Unplaced

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 11541154Exportin-4PRO_0000237670Add
BLAST

Proteomic databases

PaxDbiQ5ZMR9.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000027623.

Structurei

3D structure databases

ProteinModelPortaliQ5ZMR9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the exportin family.Curated

Phylogenomic databases

eggNOGiKOG4541. Eukaryota.
ENOG410XNNN. LUCA.
HOGENOMiHOG000154878.
HOVERGENiHBG023214.
InParanoidiQ5ZMR9.
PhylomeDBiQ5ZMR9.

Family and domain databases

InterProiIPR016024. ARM-type_fold.
IPR014877. CRM1_C_dom.
[Graphical view]
PfamiPF08767. CRM1_C. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 5 hits.

Sequencei

Sequence statusi: Complete.

Q5ZMR9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMAAAAAAGG APEVIAQLEN AAKVLMAPPS MVNNEQRQHA EHIFLSFRKS
60 70 80 90 100
KSPFAVCKHI LETSKVDYVL FQAATAIMEA VVREWILLEK TSIESLRTFL
110 120 130 140 150
LTYVLQRPNL QKYVREQILL AVAVIVKRGS LDKSIDCKSI FHEVSQLISS
160 170 180 190 200
GNPTVQTLAC SILTALLSEF SSSSKTSNIG LSMEFHGNCK RIFQEDDLRQ
210 220 230 240 250
IFMLTVEVLQ EFRRRENLNA QMSSVFQRYL ALANQVLSWN FLPPNLGRHY
260 270 280 290 300
IAMFESSQNV MLKPTESWRE TLLDSRVMEL FFTVHRKIRE DTDMAQDSLQ
310 320 330 340 350
CLAQLASLHG SVFPDEGSQV DYLAHFIEGL LNTISGIEIE DSEAVGISSI
360 370 380 390 400
ISNLITVFPR NILTAIPNEL FSSFVNCLAH LTCSFGRSAA LEEVLDKDDM
410 420 430 440 450
VYMEAYDKLL ESWLTLVQDD KHFHKGFFTQ HAVQVFNSYI QCHLAAPDGT
460 470 480 490 500
RNLTANGVAS REEEEISELQ EDDRDQFCDQ LASVGMLGRI AAEHCIPLLT
510 520 530 540 550
SLLEDRVTRL HGQLQRHQQQ LLASPASGSI DNKVLDDLYE DIHWLILVTG
560 570 580 590 600
YLLANDTQGE TPLIPPEVME YSIKHSTEVD INTTLQILGS PGEKASSIPG
610 620 630 640 650
YNRTDSVIRL LSAILRVSEV ESRAIRANLT HLLSPQMGKD IVWFLKRWAK
660 670 680 690 700
TYLLADEKLY DQISLPFSTA FGADTEGSQW IVGYLLEKVI SNLAVWSSEQ
710 720 730 740 750
DLANDTVQLL VTLVERRERA NLVIQCENWW NLAKQFARRS PPLHYLSSSV
760 770 780 790 800
QRTLMKALVL GGFAHMDTEM KQQYWTEVLQ PLQQRFLNVI NQENFQQICQ
810 820 830 840 850
EEEVKQEITA TLEALCGIAE ATQIDNVAIL FNFLMDFLNN CIGLMEVYKN
860 870 880 890 900
TPETVNLIIE VFVEVAHKQI CYLGEAKAMN LYEACLTLLQ VYSKNNLGRQ
910 920 930 940 950
RIDVTAEEDQ YQDLLLIMEL LTNLLSKEFI DFSDTDEVFR GHEPGQATNR
960 970 980 990 1000
TVSAADVVLY GVNLVLPLMS QDLLKFPSLC NQYYKLITFI CEIFPEKIPQ
1010 1020 1030 1040 1050
LPEDLFKSLM YSLELGMSSM SSEVCQLCLE AVTPLAEQCA KAQETDSALF
1060 1070 1080 1090 1100
LATRHFLKMV FDMLVLQKHN TEMTTAAGEA FYTLVCLHQA EYSELVETLL
1110 1120 1130 1140 1150
STQQDPVIYQ RLADAFNKLT ASSTPPTLDR KQKMAFLKSL EEFMANVGGL

LCVK
Length:1,154
Mass (Da):130,317
Last modified:November 23, 2004 - v1
Checksum:i4FA6B885AD14A62C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ719315 mRNA. Translation: CAG30974.1.
RefSeqiNP_001012965.1. NM_001012947.1.
UniGeneiGga.13846.

Genome annotation databases

GeneIDi428081.
KEGGigga:428081.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ719315 mRNA. Translation: CAG30974.1.
RefSeqiNP_001012965.1. NM_001012947.1.
UniGeneiGga.13846.

3D structure databases

ProteinModelPortaliQ5ZMR9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000027623.

Proteomic databases

PaxDbiQ5ZMR9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi428081.
KEGGigga:428081.

Organism-specific databases

CTDi64328.

Phylogenomic databases

eggNOGiKOG4541. Eukaryota.
ENOG410XNNN. LUCA.
HOGENOMiHOG000154878.
HOVERGENiHBG023214.
InParanoidiQ5ZMR9.
PhylomeDBiQ5ZMR9.

Miscellaneous databases

PROiQ5ZMR9.

Family and domain databases

InterProiIPR016024. ARM-type_fold.
IPR014877. CRM1_C_dom.
[Graphical view]
PfamiPF08767. CRM1_C. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 5 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiXPO4_CHICK
AccessioniPrimary (citable) accession number: Q5ZMR9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: November 23, 2004
Last modified: June 8, 2016
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.