Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein fem-1 homolog B

Gene

FEM1B

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis (By similarity).By similarity

Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

GO - Biological processi

Keywordsi

Biological processApoptosis, Ubl conjugation pathway

Enzyme and pathway databases

UniPathwayiUPA00143.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein fem-1 homolog B
Short name:
FEM1b
Alternative name(s):
FEM1-beta
Gene namesi
Name:FEM1B
ORF Names:RCJMB04_3b14
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003245331 – 627Protein fem-1 homolog BAdd BLAST627

Proteomic databases

PRIDEiQ5ZM55.

Interactioni

Subunit structurei

Component of some E3 ubiquitin-protein ligase complex.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ5ZM55.
SMRiQ5ZM55.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati45 – 74ANK 1Add BLAST30
Repeati87 – 116ANK 2Add BLAST30
Repeati120 – 149ANK 3Add BLAST30
Repeati153 – 182ANK 4Add BLAST30
Repeati186 – 215ANK 5Add BLAST30
Repeati218 – 248ANK 6Add BLAST31
Repeati344 – 377TPRAdd BLAST34
Repeati483 – 527ANK 7Add BLAST45
Repeati531 – 568ANK 8Add BLAST38

Sequence similaritiesi

Belongs to the fem-1 family.Curated

Keywords - Domaini

ANK repeat, Repeat, TPR repeat

Phylogenomic databases

HOVERGENiHBG057774.
InParanoidiQ5ZM55.
KOiK10349.
PhylomeDBiQ5ZM55.

Family and domain databases

CDDicd00204. ANK. 2 hits.
Gene3Di1.10.10.10. 1 hit.
1.25.40.20. 4 hits.
InterProiView protein in InterPro
IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR036770. Ankyrin_rpt-contain_sf.
IPR036388. WH-like_DNA-bd_sf.
PfamiView protein in Pfam
PF00023. Ank. 1 hit.
PF12796. Ank_2. 2 hits.
PRINTSiPR01415. ANKYRIN.
SMARTiView protein in SMART
SM00248. ANK. 8 hits.
SUPFAMiSSF48403. SSF48403. 2 hits.
PROSITEiView protein in PROSITE
PS50297. ANK_REP_REGION. 2 hits.
PS50088. ANK_REPEAT. 6 hits.

Sequencei

Sequence statusi: Complete.

Q5ZM55-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEGLAGYVYK AASEGRVLTL AALLLNRSES DIKYLLGYVS QHGGQRSTPL
60 70 80 90 100
IIAARNGHTK VVRLLLEHYR VQTQQTGTVR FDGFVIDGAT ALWCAAGAGH
110 120 130 140 150
FEVVKLLVSH GANVNHTTVT NSTPLRAACF DGRLDIVKYL VENNANISIA
160 170 180 190 200
NKYDNTCLMI AAYKGHTDVV RYLLEQHADP NAKAHCGATA LHFAAEAGHL
210 220 230 240 250
EIVRELVKWK AAMMVNGHGM TPLKVAAESC KADVVELLLA HAGCNRRSRI
260 270 280 290 300
EALELLGASF ANDRENYDIM KTYHYLYLAM LERYRDSENI IEKEVLPPIE
310 320 330 340 350
AYGNRTECRT PQELESIRQD RDALHMEGLI VRERILGSDN IDVSHPIIYR
360 370 380 390 400
GAVYADNMEF EQCIKLWLHA LHLRQKGNRN THKDLLRFAQ VFSQMIHLNE
410 420 430 440 450
PVKAKDIESV LRCSVLEIEQ GMSRIKATQD DDIHTAVDNY ECNIFTFLYL
460 470 480 490 500
VCISTKTQCS EEDQSRINKQ IYNLIHLDPR TRDGSTLLHH AVNSSTPVDD
510 520 530 540 550
FHTNDVCSFP NALVTKLLLD CGADVNAVDN EGNSPLHLIV QYHRPISDFL
560 570 580 590 600
TLHSIIISLV EAGAHTDMTN KQKKTPLDKS TTGVSEILLK TQMKLSLKCL
610 620
AARAVRIYNI SYQNQIPRTL EEFVKFH
Length:627
Mass (Da):70,394
Last modified:November 23, 2004 - v1
Checksum:i8B31106D0DAE0708
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ719529 mRNA. Translation: CAG31188.1.
RefSeqiNP_001025724.1. NM_001030553.1.
UniGeneiGga.19041.

Genome annotation databases

GeneIDi415559.
KEGGigga:415559.

Similar proteinsi

Entry informationi

Entry nameiFEM1B_CHICK
AccessioniPrimary (citable) accession number: Q5ZM55
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: November 23, 2004
Last modified: October 25, 2017
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families