Reviewed,
UniProtKB/Swiss-Prot Q5ZLR5 (UCRI_CHICK)
Last modified
November 25, 2008.
Version 30.
History...
Clusters with 100%,
90%,
50% identity |
Documents (1) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Cytochrome b-c1 complex subunit Rieske, mitochondrial EC=1.10.2.2 Alternative name(s): Ubiquinol-cytochrome c reductase iron-sulfur subunit Rieske iron-sulfur protein Short name=RISP Complex III subunit 5 | ||||
| Gene names |
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| Organism | Gallus gallus (Chicken) | ||||
| Taxonomic identifier | 9031 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galliformes › Phasianidae › Phasianinae › Gallus |
Protein attributes
| Sequence length | 272 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Function | Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis By similarity. |
| Catalytic activity | QH(2) + 2 ferricytochrome c = Q + 2 ferrocytochrome c + 2 H(+). |
| Cofactor | Binds 1 2Fe-2S cluster per subunit By similarity. |
| Subunit structure | The bc1 complex contains 11 subunits: 3 respiratory subunits (cytochrome b, cytochrome c1 and Rieske/UQCRFS1), 2 core proteins (UQCRC1/QCR1 and UQCRC2/QCR2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9 and UQCR11/QCR10) By similarity. |
| Subcellular location | Mitochondrion inner membraneBy similarity. |
| Miscellaneous | The Rieske protein is a high potential 2Fe-2S protein. |
| Sequence similarities | Contains 1 Rieske domain. |
Ontologies
Keywords | |
|---|---|
| Biological process | Electron transport Respiratory chain Transport |
| Cellular component | Membrane Mitochondrion Mitochondrion inner membrane |
| Domain | Transit peptide Transmembrane |
| Ligand | 2Fe-2S Iron Iron-sulfur Metal-binding |
| Molecular function | Oxidoreductase |
Gene Ontology (GO) | |
| Biological process | electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW transportInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW mitochondrial respiratory chainInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | 2 iron, 2 sulfur cluster binding Inferred from electronic annotation. Source: InterPro electron carrier activityInferred from electronic annotation. Source: InterPro iron ion bindingInferred from electronic annotation. Source: UniProtKB-KW ubiquinol-cytochrome-c reductase activityInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||||
Molecule processing | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Transit peptide | 1 – 76 | 76 | Mitochondrion By similarity | ||||||||
| Chain | 77 – 272 | 196 | Cytochrome b-c1 complex subunit Rieske, mitochondrial | PRO_0000342403 | |||||||
Regions | |||||||||||
| Domain | 185 – 270 | 86 | Rieske | ||||||||
Sites | |||||||||||
| Metal binding | 215 | 1 | Iron-sulfur (2Fe-2S) By similarity | ||||||||
| Metal binding | 217 | 1 | Iron-sulfur (2Fe-2S); via pros nitrogen By similarity | ||||||||
| Metal binding | 234 | 1 | Iron-sulfur (2Fe-2S) By similarity | ||||||||
| Metal binding | 237 | 1 | Iron-sulfur (2Fe-2S); via pros nitrogen By similarity | ||||||||
Amino acid modifications | |||||||||||
| Disulfide bond | 220 ↔ 236 | By similarity | |||||||||
Sequences
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References
| [1] | "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis." Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P., Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P., Hayashizaki Y., Buerstedde J.-M. Genome Biol. 6:RESEARCH006.1-RESEARCH006.9(2005) [PubMed: 15642098] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: CB. Tissue: Bursa of Fabricius. |
Cross-references
Sequence databases | |
|---|---|
| AJ719669 mRNA. Translation: CAG31328.1. | |
| RefSeq | NP_001005843.1. |
| UniGene | Gga.5791 |
3D structure databases | |
| SMR | Q5ZLR5. Positions 78-272. |
| ModBase | Search... |
Genome annotation databases | |
| Ensembl | ENSGALG00000004452. Gallus gallus. [Contig view] |
| GeneID | 415752. |
| KEGG | gga:415752. |
Phylogenomic databases | |
| HOVERGEN | Q5ZLR5. |
Family and domain databases | |
| InterPro | IPR014349. Rieske. IPR005805. Rieske_C. IPR006317. Rieske_proteo. IPR005806. Rieske_reg. IPR015248. Ubiq_cytc_red_N. IPR004192. UCR_TM_region. [Graphical view] |
| Gene3D | G3DSA:2.102.10.10. Rieske_reg. 1 hit. |
| PANTHER | PTHR10134. Rieske. 1 hit. |
| Pfam | PF00355. Rieske. 1 hit. PF09165. Ubiq-Cytc-red_N. 1 hit. PF02921. UCR_TM. 1 hit. [Graphical view] |
| PRINTS | PR00162. RIESKE. |
| TIGRFAMs | TIGR01416. Rieske_proteo. 1 hit. |
| PROSITE | PS51296. RIESKE. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | UCRI_CHICK | ||||||||
| Accession | Primary (citable) accession number: Q5ZLR5 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||

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