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Protein

ATP-dependent RNA helicase DDX55

Gene

DDX55

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Probable ATP-binding RNA helicase.

Catalytic activityi

ATP + H2O = ADP + phosphate.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi53 – 60ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Helicase, Hydrolase

Keywords - Ligandi

ATP-binding, Nucleotide-binding, RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ATP-dependent RNA helicase DDX55 (EC:3.6.4.13)
Alternative name(s):
DEAD box protein 55
Gene namesi
Name:DDX55
ORF Names:RCJMB04_5g4
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Unplaced

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002522121 – 591ATP-dependent RNA helicase DDX55Add BLAST591

Proteomic databases

PaxDbiQ5ZLN8.
PRIDEiQ5ZLN8.

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000005215.

Structurei

3D structure databases

ProteinModelPortaliQ5ZLN8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini40 – 223Helicase ATP-bindingPROSITE-ProRule annotationAdd BLAST184
Domaini254 – 402Helicase C-terminalPROSITE-ProRule annotationAdd BLAST149

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili486 – 542Sequence analysisAdd BLAST57

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi9 – 37Q motifAdd BLAST29
Motifi171 – 174DEAD box4

Domaini

The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

Sequence similaritiesi

Contains 1 helicase ATP-binding domain.PROSITE-ProRule annotation
Contains 1 helicase C-terminal domain.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG0345. Eukaryota.
ENOG410XNT7. LUCA.
HOGENOMiHOG000268803.
HOVERGENiHBG107796.
InParanoidiQ5ZLN8.
KOiK14809.
PhylomeDBiQ5ZLN8.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR011545. DEAD/DEAH_box_helicase_dom.
IPR025313. DUF4217.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR000629. RNA-helicase_DEAD-box_CS.
IPR014014. RNA_helicase_DEAD_Q_motif.
[Graphical view]
PfamiPF00270. DEAD. 1 hit.
PF13959. DUF4217. 1 hit.
PF00271. Helicase_C. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
SM01178. DUF4217. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00039. DEAD_ATP_HELICASE. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS51195. Q_MOTIF. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5ZLN8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEAVTEGGWS SLPVALSPGV LRALQDLGFD RMTPVQSATI PLFMSNKDVA
60 70 80 90 100
AEAVTGSGKT LAFVIPILEI LLRREEKLKK MQVGAIIITP TRELAIQIDE
110 120 130 140 150
VLTHFTKHFP KFSQILLIGG RNPMEDVEKF KEHGGNIIVA TPGRLEDLFR
160 170 180 190 200
RKADGLDLAS CVKSLDVLVL DEADRLLDMG FESSLNAILA FLPKQRRTGL
210 220 230 240 250
FSATQTQEVE NLVRAGLRNP VRISVKEKGV AATNTQKTPT RLENYYMICK
260 270 280 290 300
ADEKFNQLVH FLRQHKQEKH LVFFSTCACV EYYGKALESL IKQVKIMCIH
310 320 330 340 350
GKMKHKRNKI FTEFRRLAGG ILVCTDVMAR GIDIPEVHWV LQYDPPSSAS
360 370 380 390 400
AFVHRCGRTA RIGNAGSALV FLLPMEESYI NFLSINQKCP MQEMQPQRNV
410 420 430 440 450
LDLLPKLKSM ALADRAVFEK GMKAFVSYIQ AYAKHECNLI FRIKDLDFAS
460 470 480 490 500
LAKGFALLKM PKMPELRGKC FPDFTPVTVN TDSIPFKDKN REKQRQKQLE
510 520 530 540 550
QQRKEREESE GKKKFIKNKS WSKQKAKREK KRKLTAKRKR EEGSDMEDED
560 570 580 590
MEELLNDTRL LKRLKKGKIS EEEFEKRLTG SQSKFKEAAA D
Length:591
Mass (Da):67,242
Last modified:November 23, 2004 - v1
Checksum:iAB9E2A82987E2AF9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ719696 mRNA. Translation: CAG31355.1.
RefSeqiNP_001006185.1. NM_001006185.1.
UniGeneiGga.42731.

Genome annotation databases

GeneIDi416820.
KEGGigga:416820.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ719696 mRNA. Translation: CAG31355.1.
RefSeqiNP_001006185.1. NM_001006185.1.
UniGeneiGga.42731.

3D structure databases

ProteinModelPortaliQ5ZLN8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000005215.

Proteomic databases

PaxDbiQ5ZLN8.
PRIDEiQ5ZLN8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi416820.
KEGGigga:416820.

Organism-specific databases

CTDi57696.

Phylogenomic databases

eggNOGiKOG0345. Eukaryota.
ENOG410XNT7. LUCA.
HOGENOMiHOG000268803.
HOVERGENiHBG107796.
InParanoidiQ5ZLN8.
KOiK14809.
PhylomeDBiQ5ZLN8.

Miscellaneous databases

PROiQ5ZLN8.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR011545. DEAD/DEAH_box_helicase_dom.
IPR025313. DUF4217.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR000629. RNA-helicase_DEAD-box_CS.
IPR014014. RNA_helicase_DEAD_Q_motif.
[Graphical view]
PfamiPF00270. DEAD. 1 hit.
PF13959. DUF4217. 1 hit.
PF00271. Helicase_C. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
SM01178. DUF4217. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00039. DEAD_ATP_HELICASE. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS51195. Q_MOTIF. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDDX55_CHICK
AccessioniPrimary (citable) accession number: Q5ZLN8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: November 23, 2004
Last modified: June 8, 2016
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.