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Protein

Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C

Gene

ANKRD52

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C
Short name:
PP6-ARS-C
Short name:
Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C
Gene namesi
Name:ANKRD52
ORF Names:RCJMB04_6l3
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Unplaced

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002445891 – 1073Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit CAdd BLAST1073

Proteomic databases

PaxDbiQ5ZLC8.

Interactioni

Subunit structurei

Protein phosphatase 6 (PP6) holoenzyme is proposed to be a heterotrimeric complex formed by the catalytic subunit, a SAPS domain-containing subunit (PP6R) and an ankyrin repeat-domain containing regulatory subunit (ARS).By similarity

Protein-protein interaction databases

STRINGi9031.ENSGALP00000023054.

Structurei

3D structure databases

ProteinModelPortaliQ5ZLC8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati7 – 36ANK 1Add BLAST30
Repeati40 – 69ANK 2Add BLAST30
Repeati73 – 102ANK 3Add BLAST30
Repeati106 – 135ANK 4Add BLAST30
Repeati139 – 168ANK 5Add BLAST30
Repeati172 – 201ANK 6Add BLAST30
Repeati205 – 234ANK 7Add BLAST30
Repeati238 – 267ANK 8Add BLAST30
Repeati271 – 301ANK 9Add BLAST31
Repeati305 – 334ANK 10Add BLAST30
Repeati338 – 367ANK 11Add BLAST30
Repeati371 – 400ANK 12Add BLAST30
Repeati422 – 451ANK 13Add BLAST30
Repeati455 – 484ANK 14Add BLAST30
Repeati488 – 544ANK 15Add BLAST57
Repeati548 – 578ANK 16Add BLAST31
Repeati583 – 612ANK 17Add BLAST30
Repeati616 – 645ANK 18Add BLAST30
Repeati650 – 679ANK 19Add BLAST30
Repeati686 – 715ANK 20Add BLAST30
Repeati719 – 748ANK 21Add BLAST30
Repeati752 – 781ANK 22Add BLAST30
Repeati789 – 818ANK 23Add BLAST30
Repeati821 – 851ANK 24Add BLAST31
Repeati856 – 885ANK 25Add BLAST30
Repeati889 – 919ANK 26Add BLAST31
Repeati923 – 952ANK 27Add BLAST30
Repeati959 – 988ANK 28Add BLAST30

Sequence similaritiesi

Contains 28 ANK repeats.PROSITE-ProRule annotation

Keywords - Domaini

ANK repeat, Repeat

Phylogenomic databases

eggNOGiKOG0504. Eukaryota.
COG0666. LUCA.
HOGENOMiHOG000033959.
HOVERGENiHBG067697.
InParanoidiQ5ZLC8.
KOiK15504.
PhylomeDBiQ5ZLC8.

Family and domain databases

Gene3Di1.25.40.20. 4 hits.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view]
PfamiPF00023. Ank. 2 hits.
PF12796. Ank_2. 9 hits.
[Graphical view]
PRINTSiPR01415. ANKYRIN.
SMARTiSM00248. ANK. 28 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 3 hits.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 21 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5ZLC8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGILSITDQP PLVQAIFNRD VEEVRSLLNQ KENINVLDQE RRTPLHTAAY
60 70 80 90 100
IGDVAILELL ILSGANVNAK DTVWLTPLHR AAASRNEKAL HLLLKHSADV
110 120 130 140 150
NARDKYWQTP LHVAAANRAT KCVEAIIPLL STVNVADRTG RTALHHAVHS
160 170 180 190 200
GHLEMVNLLL NKGASLSTCD KKDRQPIHWA AFLGHLEVLK LLVARGADVM
210 220 230 240 250
CKDKKGYTLL HTAAASGQIE VVRHLLRLGV EIDEPNSFGN TALHIACYMG
260 270 280 290 300
QDAVANELVN YGANVNQPNE KGFTPLHFAA VSTNGALCLE LLVNNGADVN
310 320 330 340 350
FQSKEGKSPL HMAAIHGRFT RSQILIQNGS EIDCADKYGN TPLHVAARYG
360 370 380 390 400
HELLISTLMT NGADTARRGI HDMFPLHLAV LFGFSDCCRK LLSSGQLYSI
410 420 430 440 450
VSSLSNEHVL SAGFDINTPD NLGRTCLHAA ASGGNVECLN LLLSSGADLR
460 470 480 490 500
RRDKFGRTPL HYAAANGSYQ CTVTLVTAGA SINEADCKGC TPLHYAAASD
510 520 530 540 550
TYRRAETHSG NSHDTDEEPL KESRMKEAFF CLEFLLDNGA DPSLRDKQGY
560 570 580 590 600
TAVHYAAAYG NRQNLELLLE MSFNCLEDVE STIPVSPLHL AAYNGHCEAL
610 620 630 640 650
KTLAETLVNL DVRDHKGRTA LYLATERGST ECVEVLTSHG ASALVKERKR
660 670 680 690 700
KWTPLHAAAA NGNTDSLHLL IDSGERADIT DVMDIHGQTP LMLAIMNGHV
710 720 730 740 750
DCVHLLLEKG STADAADKRG RTALHRGAVT GCEDCLAALL DHDAFVLCRD
760 770 780 790 800
FKGRTPIHFA SACGHLEILR TLLQAALSTD PLDSVVDYSG YSPMHWASYS
810 820 830 840 850
GHEDCLELLL EHNPFAYLEG NPFTPLHCAV INNQDSTAEM LVEALGAKIV
860 870 880 890 900
NSRDAKGRTP LHAAAFADNI HGLQLLLRHQ AEVDTTDKLG RTPLMMASEN
910 920 930 940 950
GHTAAVEFLL YQAKANITVL DVNKNTALHL ACSKGHEKCA LLILGETQDL
960 970 980 990 1000
GLINASNSAL QMPLHIAARN GLATVVQALL SRGATVLAVD EEGHTPALAC
1010 1020 1030 1040 1050
APNKDVADCL ALILSTMKPF PPKDAISSFS FNLLKNCGIA AKTAACGALP
1060 1070
NGSTCPYSKD RHNAIGLDGC YSE
Length:1,073
Mass (Da):115,863
Last modified:November 23, 2004 - v1
Checksum:iABBF9E1FA801CE46
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ719806 mRNA. Translation: CAG31465.1.
RefSeqiNP_001012957.1. NM_001012939.1.
UniGeneiGga.17460.

Genome annotation databases

GeneIDi426469.
KEGGigga:426469.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ719806 mRNA. Translation: CAG31465.1.
RefSeqiNP_001012957.1. NM_001012939.1.
UniGeneiGga.17460.

3D structure databases

ProteinModelPortaliQ5ZLC8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000023054.

Proteomic databases

PaxDbiQ5ZLC8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi426469.
KEGGigga:426469.

Organism-specific databases

CTDi283373.

Phylogenomic databases

eggNOGiKOG0504. Eukaryota.
COG0666. LUCA.
HOGENOMiHOG000033959.
HOVERGENiHBG067697.
InParanoidiQ5ZLC8.
KOiK15504.
PhylomeDBiQ5ZLC8.

Miscellaneous databases

PROiQ5ZLC8.

Family and domain databases

Gene3Di1.25.40.20. 4 hits.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view]
PfamiPF00023. Ank. 2 hits.
PF12796. Ank_2. 9 hits.
[Graphical view]
PRINTSiPR01415. ANKYRIN.
SMARTiSM00248. ANK. 28 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 3 hits.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 21 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiANR52_CHICK
AccessioniPrimary (citable) accession number: Q5ZLC8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: November 23, 2004
Last modified: October 5, 2016
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.