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Protein

Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C

Gene

ANKRD52

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C
Short name:
PP6-ARS-C
Short name:
Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C
Gene namesi
Name:ANKRD52
ORF Names:RCJMB04_6l3
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Unplaced

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 10731073Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit CPRO_0000244589Add
BLAST

Proteomic databases

PaxDbiQ5ZLC8.

Interactioni

Subunit structurei

Protein phosphatase 6 (PP6) holoenzyme is proposed to be a heterotrimeric complex formed by the catalytic subunit, a SAPS domain-containing subunit (PP6R) and an ankyrin repeat-domain containing regulatory subunit (ARS).By similarity

Protein-protein interaction databases

STRINGi9031.ENSGALP00000023054.

Structurei

3D structure databases

ProteinModelPortaliQ5ZLC8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati7 – 3630ANK 1Add
BLAST
Repeati40 – 6930ANK 2Add
BLAST
Repeati73 – 10230ANK 3Add
BLAST
Repeati106 – 13530ANK 4Add
BLAST
Repeati139 – 16830ANK 5Add
BLAST
Repeati172 – 20130ANK 6Add
BLAST
Repeati205 – 23430ANK 7Add
BLAST
Repeati238 – 26730ANK 8Add
BLAST
Repeati271 – 30131ANK 9Add
BLAST
Repeati305 – 33430ANK 10Add
BLAST
Repeati338 – 36730ANK 11Add
BLAST
Repeati371 – 40030ANK 12Add
BLAST
Repeati422 – 45130ANK 13Add
BLAST
Repeati455 – 48430ANK 14Add
BLAST
Repeati488 – 54457ANK 15Add
BLAST
Repeati548 – 57831ANK 16Add
BLAST
Repeati583 – 61230ANK 17Add
BLAST
Repeati616 – 64530ANK 18Add
BLAST
Repeati650 – 67930ANK 19Add
BLAST
Repeati686 – 71530ANK 20Add
BLAST
Repeati719 – 74830ANK 21Add
BLAST
Repeati752 – 78130ANK 22Add
BLAST
Repeati789 – 81830ANK 23Add
BLAST
Repeati821 – 85131ANK 24Add
BLAST
Repeati856 – 88530ANK 25Add
BLAST
Repeati889 – 91931ANK 26Add
BLAST
Repeati923 – 95230ANK 27Add
BLAST
Repeati959 – 98830ANK 28Add
BLAST

Sequence similaritiesi

Contains 28 ANK repeats.PROSITE-ProRule annotation

Keywords - Domaini

ANK repeat, Repeat

Phylogenomic databases

eggNOGiKOG0504. Eukaryota.
COG0666. LUCA.
HOGENOMiHOG000033959.
HOVERGENiHBG067697.
InParanoidiQ5ZLC8.
KOiK15504.
PhylomeDBiQ5ZLC8.

Family and domain databases

Gene3Di1.25.40.20. 4 hits.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view]
PfamiPF00023. Ank. 1 hit.
PF12796. Ank_2. 9 hits.
[Graphical view]
PRINTSiPR01415. ANKYRIN.
SMARTiSM00248. ANK. 28 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 3 hits.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 21 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5ZLC8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGILSITDQP PLVQAIFNRD VEEVRSLLNQ KENINVLDQE RRTPLHTAAY
60 70 80 90 100
IGDVAILELL ILSGANVNAK DTVWLTPLHR AAASRNEKAL HLLLKHSADV
110 120 130 140 150
NARDKYWQTP LHVAAANRAT KCVEAIIPLL STVNVADRTG RTALHHAVHS
160 170 180 190 200
GHLEMVNLLL NKGASLSTCD KKDRQPIHWA AFLGHLEVLK LLVARGADVM
210 220 230 240 250
CKDKKGYTLL HTAAASGQIE VVRHLLRLGV EIDEPNSFGN TALHIACYMG
260 270 280 290 300
QDAVANELVN YGANVNQPNE KGFTPLHFAA VSTNGALCLE LLVNNGADVN
310 320 330 340 350
FQSKEGKSPL HMAAIHGRFT RSQILIQNGS EIDCADKYGN TPLHVAARYG
360 370 380 390 400
HELLISTLMT NGADTARRGI HDMFPLHLAV LFGFSDCCRK LLSSGQLYSI
410 420 430 440 450
VSSLSNEHVL SAGFDINTPD NLGRTCLHAA ASGGNVECLN LLLSSGADLR
460 470 480 490 500
RRDKFGRTPL HYAAANGSYQ CTVTLVTAGA SINEADCKGC TPLHYAAASD
510 520 530 540 550
TYRRAETHSG NSHDTDEEPL KESRMKEAFF CLEFLLDNGA DPSLRDKQGY
560 570 580 590 600
TAVHYAAAYG NRQNLELLLE MSFNCLEDVE STIPVSPLHL AAYNGHCEAL
610 620 630 640 650
KTLAETLVNL DVRDHKGRTA LYLATERGST ECVEVLTSHG ASALVKERKR
660 670 680 690 700
KWTPLHAAAA NGNTDSLHLL IDSGERADIT DVMDIHGQTP LMLAIMNGHV
710 720 730 740 750
DCVHLLLEKG STADAADKRG RTALHRGAVT GCEDCLAALL DHDAFVLCRD
760 770 780 790 800
FKGRTPIHFA SACGHLEILR TLLQAALSTD PLDSVVDYSG YSPMHWASYS
810 820 830 840 850
GHEDCLELLL EHNPFAYLEG NPFTPLHCAV INNQDSTAEM LVEALGAKIV
860 870 880 890 900
NSRDAKGRTP LHAAAFADNI HGLQLLLRHQ AEVDTTDKLG RTPLMMASEN
910 920 930 940 950
GHTAAVEFLL YQAKANITVL DVNKNTALHL ACSKGHEKCA LLILGETQDL
960 970 980 990 1000
GLINASNSAL QMPLHIAARN GLATVVQALL SRGATVLAVD EEGHTPALAC
1010 1020 1030 1040 1050
APNKDVADCL ALILSTMKPF PPKDAISSFS FNLLKNCGIA AKTAACGALP
1060 1070
NGSTCPYSKD RHNAIGLDGC YSE
Length:1,073
Mass (Da):115,863
Last modified:November 23, 2004 - v1
Checksum:iABBF9E1FA801CE46
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ719806 mRNA. Translation: CAG31465.1.
RefSeqiNP_001012957.1. NM_001012939.1.
UniGeneiGga.17460.

Genome annotation databases

GeneIDi426469.
KEGGigga:426469.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ719806 mRNA. Translation: CAG31465.1.
RefSeqiNP_001012957.1. NM_001012939.1.
UniGeneiGga.17460.

3D structure databases

ProteinModelPortaliQ5ZLC8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000023054.

Proteomic databases

PaxDbiQ5ZLC8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi426469.
KEGGigga:426469.

Organism-specific databases

CTDi283373.

Phylogenomic databases

eggNOGiKOG0504. Eukaryota.
COG0666. LUCA.
HOGENOMiHOG000033959.
HOVERGENiHBG067697.
InParanoidiQ5ZLC8.
KOiK15504.
PhylomeDBiQ5ZLC8.

Miscellaneous databases

PROiQ5ZLC8.

Family and domain databases

Gene3Di1.25.40.20. 4 hits.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view]
PfamiPF00023. Ank. 1 hit.
PF12796. Ank_2. 9 hits.
[Graphical view]
PRINTSiPR01415. ANKYRIN.
SMARTiSM00248. ANK. 28 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 3 hits.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 21 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiANR52_CHICK
AccessioniPrimary (citable) accession number: Q5ZLC8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: November 23, 2004
Last modified: June 8, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.