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Protein

Syntaxin-6

Gene

STX6

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Involved in intracellular vesicle trafficking.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Enzyme and pathway databases

ReactomeiR-GGA-6811438. Intra-Golgi traffic.

Names & Taxonomyi

Protein namesi
Recommended name:
Syntaxin-6
Gene namesi
Name:STX6
ORF Names:RCJMB04_8d16
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 8

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 233233CytoplasmicSequence analysisAdd
BLAST
Transmembranei234 – 25421Helical; Anchor for type IV membrane proteinSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 254254Syntaxin-6PRO_0000210212Add
BLAST

Proteomic databases

PaxDbiQ5ZL19.

Expressioni

Gene expression databases

BgeeiENSGALG00000003880.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000006160.

Structurei

3D structure databases

ProteinModelPortaliQ5ZL19.
SMRiQ5ZL19. Positions 4-109, 169-231.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini162 – 22463t-SNARE coiled-coil homologyPROSITE-ProRule annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili46 – 7227Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the syntaxin family.Curated
Contains 1 t-SNARE coiled-coil homology domain.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3202. Eukaryota.
ENOG410ZZA3. LUCA.
GeneTreeiENSGT00390000008991.
HOGENOMiHOG000237350.
HOVERGENiHBG007194.
InParanoidiQ5ZL19.
KOiK08498.
OMAiQVVREMK.
OrthoDBiEOG091G0KE5.
PhylomeDBiQ5ZL19.

Family and domain databases

InterProiIPR015260. Syntaxin-6_N.
IPR006012. Syntaxin/epimorphin_CS.
IPR010989. t-SNARE.
IPR000727. T_SNARE_dom.
[Graphical view]
PfamiPF05739. SNARE. 1 hit.
PF09177. Syntaxin-6_N. 1 hit.
[Graphical view]
SMARTiSM00397. t_SNARE. 1 hit.
[Graphical view]
SUPFAMiSSF47661. SSF47661. 1 hit.
PROSITEiPS00914. SYNTAXIN. 1 hit.
PS50192. T_SNARE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5ZL19-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSMEDPFFVV KGEVQKAVNT AQGLFQRWTE LLQDPSIATR EEIDWTTNEL
60 70 80 90 100
RNNLRSIEWD LEDLDETISI VEANPRKFNL DATELGIRKS FITSTRQVVR
110 120 130 140 150
EMKDQMSNSS MQALAERKNR QALLGESSSQ SWSSGPDKYS RLDRELQLAN
160 170 180 190 200
SHFIEEQQAQ QQLIVEQQDE QLELVSGSIG VLKNMSQRIG GELEEQAVML
210 220 230 240 250
DDFSHELDST HSRLDNVMKK LAKVSHMTSD RRQWCAIIVL FVILLVVLVL

FLVL
Length:254
Mass (Da):29,155
Last modified:November 23, 2004 - v1
Checksum:i704D97BCE83317AD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ719915 mRNA. Translation: CAG31574.1.
RefSeqiNP_001006531.1. NM_001006531.1.
UniGeneiGga.8261.

Genome annotation databases

EnsembliENSGALT00000006170; ENSGALP00000006160; ENSGALG00000003880.
GeneIDi424413.
KEGGigga:424413.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ719915 mRNA. Translation: CAG31574.1.
RefSeqiNP_001006531.1. NM_001006531.1.
UniGeneiGga.8261.

3D structure databases

ProteinModelPortaliQ5ZL19.
SMRiQ5ZL19. Positions 4-109, 169-231.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000006160.

Proteomic databases

PaxDbiQ5ZL19.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSGALT00000006170; ENSGALP00000006160; ENSGALG00000003880.
GeneIDi424413.
KEGGigga:424413.

Organism-specific databases

CTDi10228.

Phylogenomic databases

eggNOGiKOG3202. Eukaryota.
ENOG410ZZA3. LUCA.
GeneTreeiENSGT00390000008991.
HOGENOMiHOG000237350.
HOVERGENiHBG007194.
InParanoidiQ5ZL19.
KOiK08498.
OMAiQVVREMK.
OrthoDBiEOG091G0KE5.
PhylomeDBiQ5ZL19.

Enzyme and pathway databases

ReactomeiR-GGA-6811438. Intra-Golgi traffic.

Miscellaneous databases

PROiQ5ZL19.

Gene expression databases

BgeeiENSGALG00000003880.

Family and domain databases

InterProiIPR015260. Syntaxin-6_N.
IPR006012. Syntaxin/epimorphin_CS.
IPR010989. t-SNARE.
IPR000727. T_SNARE_dom.
[Graphical view]
PfamiPF05739. SNARE. 1 hit.
PF09177. Syntaxin-6_N. 1 hit.
[Graphical view]
SMARTiSM00397. t_SNARE. 1 hit.
[Graphical view]
SUPFAMiSSF47661. SSF47661. 1 hit.
PROSITEiPS00914. SYNTAXIN. 1 hit.
PS50192. T_SNARE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSTX6_CHICK
AccessioniPrimary (citable) accession number: Q5ZL19
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: November 23, 2004
Last modified: September 7, 2016
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.