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Protein

WD repeat domain phosphoinositide-interacting protein 3

Gene

WDR45B

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-GGA-1632852 Macroautophagy

Names & Taxonomyi

Protein namesi
Recommended name:
WD repeat domain phosphoinositide-interacting protein 3
Short name:
WIPI-3
Alternative name(s):
WD repeat-containing protein 45B
Gene namesi
Name:WDR45B
Synonyms:WIPI3
ORF Names:RCJMB04_8d21
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 18

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000514481 – 344WD repeat domain phosphoinositide-interacting protein 3Add BLAST344

Proteomic databases

PaxDbiQ5ZL16

Expressioni

Gene expression databases

BgeeiENSGALG00000001563

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000002372

Structurei

3D structure databases

ProteinModelPortaliQ5ZL16
SMRiQ5ZL16
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati183 – 223WD 1Add BLAST41
Repeati228 – 267WD 2Add BLAST40

Sequence similaritiesi

Belongs to the WD repeat SVP1 family.Curated

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

eggNOGiKOG2111 Eukaryota
ENOG410XQZ6 LUCA
GeneTreeiENSGT00730000110940
HOGENOMiHOG000217543
HOVERGENiHBG053275
InParanoidiQ5ZL16
OMAiYCINFNH
OrthoDBiEOG091G0EJZ
PhylomeDBiQ5ZL16
TreeFamiTF314859

Family and domain databases

Gene3Di2.130.10.101 hit
InterProiView protein in InterPro
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR036322 WD40_repeat_dom_sf
SMARTiView protein in SMART
SM00320 WD40, 2 hits
SUPFAMiSSF50978 SSF50978, 1 hit

Sequencei

Sequence statusi: Complete.

Q5ZL16-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLLPANPHG NGLLYAGFNQ DHGCFACGME NGFRVYNADP LKEKEKQEFP
60 70 80 90 100
EGGVGHVEML FRCNYLALVG GGKKPKYPPN KVMIWDDLKK KTVIEIEFST
110 120 130 140 150
EVKAVKLRRD RIVVVLDSMI KVFTFTHNPH QLHVFETCYN PKGLCVLCPN
160 170 180 190 200
SNNSLLAFPG THTGHVQIVD LANTEKPPVD IPAHEGILSC IALNLQGTRI
210 220 230 240 250
ATASEKGTLI RIFDTSSGHL IQELRRGSQA ANIYCINFNQ DASLICVSSD
260 270 280 290 300
HGTVHIFAAE DPKRNKQSSL ASASFLPKYF SSKWSFSKFQ VPSGSPCICA
310 320 330 340
FGTEPNAVLA ICADGSYYKF LFNQKGECSR DVYAQFLEMT DDKL
Length:344
Mass (Da):38,090
Last modified:November 23, 2004 - v1
Checksum:i99278B2D8ADA556D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ719918 mRNA Translation: CAG31577.1
RefSeqiNP_001007845.1, NM_001007844.1
UniGeneiGga.11558

Genome annotation databases

EnsembliENSGALT00000002374; ENSGALP00000002372; ENSGALG00000001563
GeneIDi417339
KEGGigga:417339

Similar proteinsi

Entry informationi

Entry nameiWIPI3_CHICK
AccessioniPrimary (citable) accession number: Q5ZL16
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: November 23, 2004
Last modified: February 28, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome