Reviewed, UniProtKB/Swiss-Prot Q5ZKZ4 (DJC16_CHICK)

Names and origin

Protein names

Recommended name:
    DnaJ homolog subfamily C member 16

Gene names

Name:	DNAJC16
ORF Names:	RCJMB04_8j20

Organism

Gallus gallus (Chicken)

Taxonomic identifier

9031 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galliformes › Phasianidae › Phasianinae › Gallus

Protein attributes

Sequence length	777 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Subcellular location	Membrane; Single-pass type IV membrane protein Potential.
Sequence similarities	Contains 1 J domain. Contains 1 thioredoxin domain.

Ontologies

Keywords
Cellular component	Membrane
Domain	Signal Transmembrane
PTM	Glycoprotein
Gene Ontology (GO)
Biological process	cell redox homeostasis Inferred from electronic annotation. Source: InterPro protein folding Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	heat shock protein binding Inferred from electronic annotation. Source: InterPro unfolded protein binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 23	23	Potential
	Chain	24 – 777	754	DnaJ homolog subfamily C member 16		PRO_0000236687
Regions
	Topological domain	24 – 531	508	Cytoplasmic Potential
	Transmembrane	532 – 552	21	Anchor for type IV membrane protein Potential
	Topological domain	553 – 777	225	Extracellular Potential
	Domain	28 – 92	65	J
	Domain	117 – 243	127	Thioredoxin
Amino acid modifications
	Glycosylation	627	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	Q5ZKZ4-1 [UniParc]. Last modified November 23, 2004. Version 1. Checksum: 0E188E795EC96FC6	FASTA	777	89,415
	10 20 30 40 50 60 MELGRAGPAG LLLLLLLLLA AQAAPERDPY RVLGVGRSSS QADIKKAYKR LARQWHPDKN 70 80 90 100 110 120 KDPGAEDKFI QISKAYEILS NEEKRANFDR YGDAGESQGY SQHQQRQFHH FHEGFYFDES 130 140 150 160 170 180 FFHFPFNSER RDTSDEKYLL HFSHYINEIV PDSFKKPYLI KITSDWCFSC IHIEPVWKEV 190 200 210 220 230 240 AQELEALGVG IGVVHAGYER RLAHHLGAHS TPSILGLING KITFFHSAVV RENLRQFVEN 250 260 270 280 290 300 LLPGNLVEKI TDKNYIRFLS NWKKENKPHV LLFDHMPVVP LLYKLTAFAY RDYLSFGYVY 310 320 330 340 350 360 VGLRGTEELS SQYNINVYTP TLMIFKEHID KPADVAQARD MKKQLIDDFL SQNKFLMAAR 370 380 390 400 410 420 LTNQRLFQEL CPVKKSHRQR KHCVVLLTGE GDKFADAYEA FLTFAVANTK DTLRFAHIYN 430 440 450 460 470 480 DRQPEFADAL LMDEEKYRGK SAVVILERRN NAGKIAYKTL EEAWQGSNED NFILLDLLDQ 490 500 510 520 530 540 LRTDPGLLSS ETVLADLNDE LAPMFLIRWF YSTLDYILDC WDSLFHSNWR EMMPLLSLLF 550 560 570 580 590 600 SALFILFGTV IVQAFSDSSD TRDSPASEKK DTTAKTEKND TSFNKESNSR VPKKGFVEVT 610 620 630 640 650 660 ELTDINYNSN LVRLRPGHMN VVLILSNSTK TALLQKFALE VYTFTGSSSL HFSFLSLDKH 670 680 690 700 710 720 REWLEYLLEF AQDAAPIPNQ YDKHFLERDY TGYVLALNGH KKYFCLFKPH RSGDEGGTLG 730 740 750 760 770 ACEDYDSSLH TEARGKSSCS PGSRSLKNKL HKLSFWMERL LEGSLQRFYI PSWPALD

References

[1]

"Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis." Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P., Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P., Hayashizaki Y., Buerstedde J.-M. Genome Biol. 6:RESEARCH006.1-RESEARCH006.9(2005) [PubMed: 15642098] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: CB. Tissue: Bursa of Fabricius.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AJ719940 mRNA. Translation: CAG31599.1.
IPI	IPI00589764.
RefSeq	NP_001034419.1.
UniGene	Gga.22525
3D structure databases
SMR	Q5ZKZ4. Positions 11-98.
ModBase	Search...
Genome annotation databases
Ensembl	ENSGALG00000013677. Gallus gallus. [Contig view]
GeneID	429208.
KEGG	gga:429208.
Phylogenomic databases
HOVERGEN	Q5ZKZ4.
Family and domain databases
InterPro	IPR001623. DnaJ_N. IPR018253. Heat_shock_DnaJ_CS. IPR015609. Hsp40/DnaJ_Rel. IPR003095. Hsp_DnaJ. IPR017936. Thioredoxin-like. IPR012335. Thioredoxin_fold. [Graphical view]
Gene3D	G3DSA:1.10.287.110. DnaJ_N. 1 hit. G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit.
PANTHER	PTHR11821. Hsp40/DnaJ_Rel. 1 hit.
Pfam	PF00226. DnaJ. 1 hit. [Graphical view]
PRINTS	PR00625. DNAJPROTEIN.
SMART	SM00271. DnaJ. 1 hit. [Graphical view]
PROSITE	PS00636. DNAJ_1. 1 hit. PS50076. DNAJ_2. 1 hit. PS51352. THIOREDOXIN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DJC16_CHICK

Accession

Primary (citable) accession number: Q5ZKZ4

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2006
Last sequence update:	November 23, 2004
Last modified:	May 5, 2009
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)