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Q5ZKB7 (AT134_CHICK) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable cation-transporting ATPase 13A4
EC=3.6.3.-
Alternative name(s):
P5-ATPase isoform 4
Gene names
Name:ATP13A4
ORF Names:RCJMB04_11o9
OrganismGallus gallus (Chicken) [Reference proteome]
Taxonomic identifier9031 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galliformes › Phasianidae › Phasianinae › Gallus

Protein attributes

Sequence length1204 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + H2O = ADP + phosphate.

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Sequence similarities

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. [View classification]

Ontologies

Keywords
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
   LigandATP-binding
Magnesium
Metal-binding
Nucleotide-binding
   Molecular functionHydrolase
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processATP catabolic process

Inferred from electronic annotation. Source: GOC

   Cellular_componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

cation-transporting ATPase activity

Inferred from electronic annotation. Source: InterPro

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 12041204Probable cation-transporting ATPase 13A4
PRO_0000318677

Regions

Topological domain1 – 3232Cytoplasmic Potential
Transmembrane33 – 5321Helical; Potential
Topological domain54 – 219166Extracellular Potential
Transmembrane220 – 24223Helical; Potential
Topological domain243 – 397155Cytoplasmic Potential
Transmembrane398 – 41821Helical; Potential
Topological domain419 – 43315Extracellular Potential
Transmembrane434 – 45421Helical; Potential
Topological domain455 – 897443Cytoplasmic Potential
Transmembrane898 – 91821Helical; Potential
Topological domain919 – 92911Extracellular Potential
Transmembrane930 – 95021Helical; Potential
Topological domain951 – 96717Cytoplasmic Potential
Transmembrane968 – 98821Helical; Potential
Topological domain989 – 104355Extracellular Potential
Transmembrane1044 – 106421Helical; Potential
Topological domain1065 – 107511Cytoplasmic Potential
Transmembrane1076 – 109621Helical; Potential
Topological domain1097 – 111317Extracellular Potential
Transmembrane1114 – 113421Helical; Potential
Topological domain1135 – 120470Cytoplasmic Potential

Sites

Active site48314-aspartylphosphate intermediate By similarity
Metal binding8451Magnesium By similarity
Metal binding8491Magnesium By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5ZKB7 [UniParc].

Last modified November 23, 2004. Version 1.
Checksum: B6AECD6FE30FFDEB

FASTA1,204134,058
        10         20         30         40         50         60 
MGENPAKSHY AQLNLGEENE MEIFGYKTQC CRKALCIAGY ILSCGALLLL FYWKPEWDVW 

        70         80         90        100        110        120 
ANCVPCSLEE ADVVLLRTTD EFRIYSRKNV TWISVSGIIK SRLDYPSFAE EDSIFSKALM 

       130        140        150        160        170        180 
KPSLQVKSIQ VQKIRYVWNI YAKQFQKVGA LEDHHTCSAI HTKFGSGLTC SEQSLRRVIC 

       190        200        210        220        230        240 
GPNTIDVPVI PIWKLLIKEV LNPFYVFQLF SVCLWFAEDY MEYAAAIIIM SPLSISLTVY 

       250        260        270        280        290        300 
DLRQQSVKLQ RLVESHNSIM VTGRNKEGFQ ELESHHLVPG DMVVLKEGKA LLPCDAILIS 

       310        320        330        340        350        360 
GQCIVNESML TGESIPVTKT QLPQADNLKP WKMHCAEDYK KHVLFCGTEV IQTKGDDRGV 

       370        380        390        400        410        420 
VKAVVLQTGF NTAKGDLVRS ILYPKPMNFR LYRDALRFLM CLIAFAAIGM IYTVCVFALN 

       430        440        450        460        470        480 
GEEAGEVVKK ALDVITIAVP PALPAALTTG IIYTQRRLKK KGIFCISPQR INMCGQLNLI 

       490        500        510        520        530        540 
CFDKTGTLTE DGLDLWGLLP SEGNCFQDVR RFPADHSLPW GPAFRAMVVC HSLIVLEGKI 

       550        560        570        580        590        600 
QGDPLDVKMF EATNWVIDDS SGHQIEGQRS THATVIRPGP KANTASVDGI TILHQFPFSS 

       610        620        630        640        650        660 
ALQRMSVIAQ ETGGEKQAFT KGAPEMVATL CRAETVPSNF ESKLLFYTAQ GFRVIGLAYK 

       670        680        690        700        710        720 
SLQSGKQSTD LTREEVESDL TFLGLLIMEN RLKRETKPVL EELSAAHIRS VMVTGDNIQT 

       730        740        750        760        770        780 
AVTVAKNAGM ISPTNRVILV EANKIPGSFS ASVTWKPLKE NKTEDDGNLD SGSQTGRRIR 

       790        800        810        820        830        840 
LAAEPGQFHF AMSGKSYQVV AQYFSHLLPK LLLNATVFAR MSPSQKSSLV EEFQKLDYFV 

       850        860        870        880        890        900 
GMCGDGANDC GALKVAHAGI SLSEQEASVA SPFTSRTPSI ACVPELIREG RAALVTSFCM 

       910        920        930        940        950        960 
FKYMALYSTI QYLGVLLLYW QLNSFGNYQF LFQDLAITTV IGMTMSFTEA YPKLVPYRPP 

       970        980        990       1000       1010       1020 
SQLVSPPLLL SVILNILFSL GMQILGFLMV QKQPWYSKTD IHSACLSVNN HVENSSSASS 

      1030       1040       1050       1060       1070       1080 
LGLHGVGGGD PTEVDNGYKS YENTTVWLLS TINCLIIALV FSKGKPFRQP IYTNYVFIMV 

      1090       1100       1110       1120       1130       1140 
LVGQLGVCLF LVFADIDDLY SKMDLVCTPT TWRISMVMML AVTLAVSFLV EEAIIENRAL 

      1150       1160       1170       1180       1190       1200 
WLWLKKTFQY HSKSHYKRLQ RVLEQDSAWP PLNETFSLDA VTVSVEEDME GHSNPTFDSN 


EDAL

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References

[1]"Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis."
Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P., Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P., Hayashizaki Y., Buerstedde J.-M.
Genome Biol. 6:R6.1-R6.9(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: CB.
Tissue: Bursa of Fabricius.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AJ720167 mRNA. Translation: CAG31826.1.
IPIIPI00587863.
RefSeqNP_001026485.1. NM_001031314.1.
UniGeneGga.22189.

3D structure databases

ProteinModelPortalQ5ZKB7.
ModBaseSearch...

Proteomic databases

PaxDbQ5ZKB7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID424901.
KEGGgga:424901.

Organism-specific databases

CTD84239.

Phylogenomic databases

eggNOGCOG0474.
HOGENOMHOG000171813.
HOVERGENHBG065757.
InParanoidQ5ZKB7.
KOK14951.
OrthoDBEOG4KH2T8.

Family and domain databases

Gene3D2.70.150.10. 1 hit.
3.40.1110.10. 1 hit.
3.40.50.1000. 2 hits.
InterProIPR004014. ATPase_P-typ_cation-transptr_N.
IPR006544. ATPase_P-typ_Cation_typ_V.
IPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR001757. Cation_transp_P_typ_ATPase.
IPR023214. HAD-like_dom.
[Graphical view]
PANTHERPTHR24093. PTHR24093. 1 hit.
PfamPF00690. Cation_ATPase_N. 1 hit.
PF00122. E1-E2_ATPase. 1 hit.
PF12409. P5-ATPase. 1 hit.
[Graphical view]
PRINTSPR00119. CATATPASE.
SMARTSM00831. Cation_ATPase_N. 1 hit.
[Graphical view]
SUPFAMSSF81660. ATPase_cation_domN. 1 hit.
SSF56784. HAD-like_dom. 1 hit.
TIGRFAMsTIGR01494. ATPase_P-type. 3 hits.
TIGR01657. P-ATPase-V. 1 hit.
PROSITEPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20827165.

Entry information

Entry nameAT134_CHICK
AccessionPrimary (citable) accession number: Q5ZKB7
Entry history
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: November 23, 2004
Last modified: May 1, 2013
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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