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Q5ZKB7

- AT134_CHICK

UniProt

Q5ZKB7 - AT134_CHICK

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Protein

Probable cation-transporting ATPase 13A4

Gene

ATP13A4

Organism
Gallus gallus (Chicken)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + H2O = ADP + phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei483 – 48314-aspartylphosphate intermediateBy similarity
Metal bindingi845 – 8451MagnesiumBy similarity
Metal bindingi849 – 8491MagnesiumBy similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. cation-transporting ATPase activity Source: InterPro
  3. metal ion binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

ATP-binding, Magnesium, Metal-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cation-transporting ATPase 13A4 (EC:3.6.3.-)
Alternative name(s):
P5-ATPase isoform 4
Gene namesi
Name:ATP13A4
ORF Names:RCJMB04_11o9
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
ProteomesiUP000000539: Unplaced

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 3232CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei33 – 5321HelicalSequence AnalysisAdd
BLAST
Topological domaini54 – 219166ExtracellularSequence AnalysisAdd
BLAST
Transmembranei220 – 24223HelicalSequence AnalysisAdd
BLAST
Topological domaini243 – 397155CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei398 – 41821HelicalSequence AnalysisAdd
BLAST
Topological domaini419 – 43315ExtracellularSequence AnalysisAdd
BLAST
Transmembranei434 – 45421HelicalSequence AnalysisAdd
BLAST
Topological domaini455 – 897443CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei898 – 91821HelicalSequence AnalysisAdd
BLAST
Topological domaini919 – 92911ExtracellularSequence AnalysisAdd
BLAST
Transmembranei930 – 95021HelicalSequence AnalysisAdd
BLAST
Topological domaini951 – 96717CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei968 – 98821HelicalSequence AnalysisAdd
BLAST
Topological domaini989 – 104355ExtracellularSequence AnalysisAdd
BLAST
Transmembranei1044 – 106421HelicalSequence AnalysisAdd
BLAST
Topological domaini1065 – 107511CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei1076 – 109621HelicalSequence AnalysisAdd
BLAST
Topological domaini1097 – 111317ExtracellularSequence AnalysisAdd
BLAST
Transmembranei1114 – 113421HelicalSequence AnalysisAdd
BLAST
Topological domaini1135 – 120470CytoplasmicSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 12041204Probable cation-transporting ATPase 13A4PRO_0000318677Add
BLAST

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ5ZKB7.

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000011610.

Structurei

3D structure databases

ProteinModelPortaliQ5ZKB7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0474.
HOGENOMiHOG000171813.
HOVERGENiHBG065757.
InParanoidiQ5ZKB7.
KOiK14951.
PhylomeDBiQ5ZKB7.

Family and domain databases

Gene3Di2.70.150.10. 1 hit.
3.40.1110.10. 1 hit.
3.40.50.1000. 2 hits.
InterProiIPR004014. ATPase_P-typ_cation-transptr_N.
IPR006544. ATPase_P-typ_Cation_typ_V.
IPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR001757. Cation_transp_P_typ_ATPase.
IPR023214. HAD-like_dom.
[Graphical view]
PfamiPF00690. Cation_ATPase_N. 1 hit.
PF00122. E1-E2_ATPase. 1 hit.
PF12409. P5-ATPase. 1 hit.
[Graphical view]
PRINTSiPR00119. CATATPASE.
SMARTiSM00831. Cation_ATPase_N. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 3 hits.
SSF81660. SSF81660. 1 hit.
TIGRFAMsiTIGR01494. ATPase_P-type. 3 hits.
TIGR01657. P-ATPase-V. 1 hit.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5ZKB7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGENPAKSHY AQLNLGEENE MEIFGYKTQC CRKALCIAGY ILSCGALLLL
60 70 80 90 100
FYWKPEWDVW ANCVPCSLEE ADVVLLRTTD EFRIYSRKNV TWISVSGIIK
110 120 130 140 150
SRLDYPSFAE EDSIFSKALM KPSLQVKSIQ VQKIRYVWNI YAKQFQKVGA
160 170 180 190 200
LEDHHTCSAI HTKFGSGLTC SEQSLRRVIC GPNTIDVPVI PIWKLLIKEV
210 220 230 240 250
LNPFYVFQLF SVCLWFAEDY MEYAAAIIIM SPLSISLTVY DLRQQSVKLQ
260 270 280 290 300
RLVESHNSIM VTGRNKEGFQ ELESHHLVPG DMVVLKEGKA LLPCDAILIS
310 320 330 340 350
GQCIVNESML TGESIPVTKT QLPQADNLKP WKMHCAEDYK KHVLFCGTEV
360 370 380 390 400
IQTKGDDRGV VKAVVLQTGF NTAKGDLVRS ILYPKPMNFR LYRDALRFLM
410 420 430 440 450
CLIAFAAIGM IYTVCVFALN GEEAGEVVKK ALDVITIAVP PALPAALTTG
460 470 480 490 500
IIYTQRRLKK KGIFCISPQR INMCGQLNLI CFDKTGTLTE DGLDLWGLLP
510 520 530 540 550
SEGNCFQDVR RFPADHSLPW GPAFRAMVVC HSLIVLEGKI QGDPLDVKMF
560 570 580 590 600
EATNWVIDDS SGHQIEGQRS THATVIRPGP KANTASVDGI TILHQFPFSS
610 620 630 640 650
ALQRMSVIAQ ETGGEKQAFT KGAPEMVATL CRAETVPSNF ESKLLFYTAQ
660 670 680 690 700
GFRVIGLAYK SLQSGKQSTD LTREEVESDL TFLGLLIMEN RLKRETKPVL
710 720 730 740 750
EELSAAHIRS VMVTGDNIQT AVTVAKNAGM ISPTNRVILV EANKIPGSFS
760 770 780 790 800
ASVTWKPLKE NKTEDDGNLD SGSQTGRRIR LAAEPGQFHF AMSGKSYQVV
810 820 830 840 850
AQYFSHLLPK LLLNATVFAR MSPSQKSSLV EEFQKLDYFV GMCGDGANDC
860 870 880 890 900
GALKVAHAGI SLSEQEASVA SPFTSRTPSI ACVPELIREG RAALVTSFCM
910 920 930 940 950
FKYMALYSTI QYLGVLLLYW QLNSFGNYQF LFQDLAITTV IGMTMSFTEA
960 970 980 990 1000
YPKLVPYRPP SQLVSPPLLL SVILNILFSL GMQILGFLMV QKQPWYSKTD
1010 1020 1030 1040 1050
IHSACLSVNN HVENSSSASS LGLHGVGGGD PTEVDNGYKS YENTTVWLLS
1060 1070 1080 1090 1100
TINCLIIALV FSKGKPFRQP IYTNYVFIMV LVGQLGVCLF LVFADIDDLY
1110 1120 1130 1140 1150
SKMDLVCTPT TWRISMVMML AVTLAVSFLV EEAIIENRAL WLWLKKTFQY
1160 1170 1180 1190 1200
HSKSHYKRLQ RVLEQDSAWP PLNETFSLDA VTVSVEEDME GHSNPTFDSN

EDAL
Length:1,204
Mass (Da):134,058
Last modified:November 23, 2004 - v1
Checksum:iB6AECD6FE30FFDEB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ720167 mRNA. Translation: CAG31826.1.
RefSeqiNP_001026485.1. NM_001031314.1.
UniGeneiGga.22189.

Genome annotation databases

GeneIDi424901.
KEGGigga:424901.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ720167 mRNA. Translation: CAG31826.1 .
RefSeqi NP_001026485.1. NM_001031314.1.
UniGenei Gga.22189.

3D structure databases

ProteinModelPortali Q5ZKB7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9031.ENSGALP00000011610.

Proteomic databases

PaxDbi Q5ZKB7.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 424901.
KEGGi gga:424901.

Organism-specific databases

CTDi 84239.

Phylogenomic databases

eggNOGi COG0474.
HOGENOMi HOG000171813.
HOVERGENi HBG065757.
InParanoidi Q5ZKB7.
KOi K14951.
PhylomeDBi Q5ZKB7.

Miscellaneous databases

NextBioi 20827165.
PROi Q5ZKB7.

Family and domain databases

Gene3Di 2.70.150.10. 1 hit.
3.40.1110.10. 1 hit.
3.40.50.1000. 2 hits.
InterProi IPR004014. ATPase_P-typ_cation-transptr_N.
IPR006544. ATPase_P-typ_Cation_typ_V.
IPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR001757. Cation_transp_P_typ_ATPase.
IPR023214. HAD-like_dom.
[Graphical view ]
Pfami PF00690. Cation_ATPase_N. 1 hit.
PF00122. E1-E2_ATPase. 1 hit.
PF12409. P5-ATPase. 1 hit.
[Graphical view ]
PRINTSi PR00119. CATATPASE.
SMARTi SM00831. Cation_ATPase_N. 1 hit.
[Graphical view ]
SUPFAMi SSF56784. SSF56784. 3 hits.
SSF81660. SSF81660. 1 hit.
TIGRFAMsi TIGR01494. ATPase_P-type. 3 hits.
TIGR01657. P-ATPase-V. 1 hit.
PROSITEi PS00154. ATPASE_E1_E2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: CB.
    Tissue: Bursa of Fabricius.

Entry informationi

Entry nameiAT134_CHICK
AccessioniPrimary (citable) accession number: Q5ZKB7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: November 23, 2004
Last modified: November 26, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3