Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q5ZKB7

- AT134_CHICK

UniProt

Q5ZKB7 - AT134_CHICK

Protein

Probable cation-transporting ATPase 13A4

Gene

ATP13A4

Organism
Gallus gallus (Chicken)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 78 (01 Oct 2014)
      Sequence version 1 (23 Nov 2004)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    ATP + H2O = ADP + phosphate.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei483 – 48314-aspartylphosphate intermediateBy similarity
    Metal bindingi845 – 8451MagnesiumBy similarity
    Metal bindingi849 – 8491MagnesiumBy similarity

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. cation-transporting ATPase activity Source: InterPro
    3. metal ion binding Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Ligandi

    ATP-binding, Magnesium, Metal-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable cation-transporting ATPase 13A4 (EC:3.6.3.-)
    Alternative name(s):
    P5-ATPase isoform 4
    Gene namesi
    Name:ATP13A4
    ORF Names:RCJMB04_11o9
    OrganismiGallus gallus (Chicken)
    Taxonomic identifieri9031 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus
    ProteomesiUP000000539: Unplaced

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 12041204Probable cation-transporting ATPase 13A4PRO_0000318677Add
    BLAST

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    PaxDbiQ5ZKB7.

    Interactioni

    Protein-protein interaction databases

    STRINGi9031.ENSGALP00000011610.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5ZKB7.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 3232CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini54 – 219166ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini243 – 397155CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini419 – 43315ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini455 – 897443CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini919 – 92911ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini951 – 96717CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini989 – 104355ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini1065 – 107511CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini1097 – 111317ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini1135 – 120470CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei33 – 5321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei220 – 24223HelicalSequence AnalysisAdd
    BLAST
    Transmembranei398 – 41821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei434 – 45421HelicalSequence AnalysisAdd
    BLAST
    Transmembranei898 – 91821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei930 – 95021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei968 – 98821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei1044 – 106421HelicalSequence AnalysisAdd
    BLAST
    Transmembranei1076 – 109621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei1114 – 113421HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0474.
    HOGENOMiHOG000171813.
    HOVERGENiHBG065757.
    InParanoidiQ5ZKB7.
    KOiK14951.
    PhylomeDBiQ5ZKB7.

    Family and domain databases

    Gene3Di2.70.150.10. 1 hit.
    3.40.1110.10. 1 hit.
    3.40.50.1000. 2 hits.
    InterProiIPR004014. ATPase_P-typ_cation-transptr_N.
    IPR006544. ATPase_P-typ_Cation_typ_V.
    IPR023299. ATPase_P-typ_cyto_domN.
    IPR018303. ATPase_P-typ_P_site.
    IPR008250. ATPase_P-typ_transduc_dom_A.
    IPR001757. Cation_transp_P_typ_ATPase.
    IPR023214. HAD-like_dom.
    [Graphical view]
    PfamiPF00690. Cation_ATPase_N. 1 hit.
    PF00122. E1-E2_ATPase. 1 hit.
    PF12409. P5-ATPase. 1 hit.
    [Graphical view]
    PRINTSiPR00119. CATATPASE.
    SMARTiSM00831. Cation_ATPase_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF56784. SSF56784. 3 hits.
    SSF81660. SSF81660. 1 hit.
    TIGRFAMsiTIGR01494. ATPase_P-type. 3 hits.
    TIGR01657. P-ATPase-V. 1 hit.
    PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5ZKB7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGENPAKSHY AQLNLGEENE MEIFGYKTQC CRKALCIAGY ILSCGALLLL     50
    FYWKPEWDVW ANCVPCSLEE ADVVLLRTTD EFRIYSRKNV TWISVSGIIK 100
    SRLDYPSFAE EDSIFSKALM KPSLQVKSIQ VQKIRYVWNI YAKQFQKVGA 150
    LEDHHTCSAI HTKFGSGLTC SEQSLRRVIC GPNTIDVPVI PIWKLLIKEV 200
    LNPFYVFQLF SVCLWFAEDY MEYAAAIIIM SPLSISLTVY DLRQQSVKLQ 250
    RLVESHNSIM VTGRNKEGFQ ELESHHLVPG DMVVLKEGKA LLPCDAILIS 300
    GQCIVNESML TGESIPVTKT QLPQADNLKP WKMHCAEDYK KHVLFCGTEV 350
    IQTKGDDRGV VKAVVLQTGF NTAKGDLVRS ILYPKPMNFR LYRDALRFLM 400
    CLIAFAAIGM IYTVCVFALN GEEAGEVVKK ALDVITIAVP PALPAALTTG 450
    IIYTQRRLKK KGIFCISPQR INMCGQLNLI CFDKTGTLTE DGLDLWGLLP 500
    SEGNCFQDVR RFPADHSLPW GPAFRAMVVC HSLIVLEGKI QGDPLDVKMF 550
    EATNWVIDDS SGHQIEGQRS THATVIRPGP KANTASVDGI TILHQFPFSS 600
    ALQRMSVIAQ ETGGEKQAFT KGAPEMVATL CRAETVPSNF ESKLLFYTAQ 650
    GFRVIGLAYK SLQSGKQSTD LTREEVESDL TFLGLLIMEN RLKRETKPVL 700
    EELSAAHIRS VMVTGDNIQT AVTVAKNAGM ISPTNRVILV EANKIPGSFS 750
    ASVTWKPLKE NKTEDDGNLD SGSQTGRRIR LAAEPGQFHF AMSGKSYQVV 800
    AQYFSHLLPK LLLNATVFAR MSPSQKSSLV EEFQKLDYFV GMCGDGANDC 850
    GALKVAHAGI SLSEQEASVA SPFTSRTPSI ACVPELIREG RAALVTSFCM 900
    FKYMALYSTI QYLGVLLLYW QLNSFGNYQF LFQDLAITTV IGMTMSFTEA 950
    YPKLVPYRPP SQLVSPPLLL SVILNILFSL GMQILGFLMV QKQPWYSKTD 1000
    IHSACLSVNN HVENSSSASS LGLHGVGGGD PTEVDNGYKS YENTTVWLLS 1050
    TINCLIIALV FSKGKPFRQP IYTNYVFIMV LVGQLGVCLF LVFADIDDLY 1100
    SKMDLVCTPT TWRISMVMML AVTLAVSFLV EEAIIENRAL WLWLKKTFQY 1150
    HSKSHYKRLQ RVLEQDSAWP PLNETFSLDA VTVSVEEDME GHSNPTFDSN 1200
    EDAL 1204
    Length:1,204
    Mass (Da):134,058
    Last modified:November 23, 2004 - v1
    Checksum:iB6AECD6FE30FFDEB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ720167 mRNA. Translation: CAG31826.1.
    RefSeqiNP_001026485.1. NM_001031314.1.
    UniGeneiGga.22189.

    Genome annotation databases

    GeneIDi424901.
    KEGGigga:424901.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ720167 mRNA. Translation: CAG31826.1 .
    RefSeqi NP_001026485.1. NM_001031314.1.
    UniGenei Gga.22189.

    3D structure databases

    ProteinModelPortali Q5ZKB7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9031.ENSGALP00000011610.

    Proteomic databases

    PaxDbi Q5ZKB7.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 424901.
    KEGGi gga:424901.

    Organism-specific databases

    CTDi 84239.

    Phylogenomic databases

    eggNOGi COG0474.
    HOGENOMi HOG000171813.
    HOVERGENi HBG065757.
    InParanoidi Q5ZKB7.
    KOi K14951.
    PhylomeDBi Q5ZKB7.

    Miscellaneous databases

    NextBioi 20827165.
    PROi Q5ZKB7.

    Family and domain databases

    Gene3Di 2.70.150.10. 1 hit.
    3.40.1110.10. 1 hit.
    3.40.50.1000. 2 hits.
    InterProi IPR004014. ATPase_P-typ_cation-transptr_N.
    IPR006544. ATPase_P-typ_Cation_typ_V.
    IPR023299. ATPase_P-typ_cyto_domN.
    IPR018303. ATPase_P-typ_P_site.
    IPR008250. ATPase_P-typ_transduc_dom_A.
    IPR001757. Cation_transp_P_typ_ATPase.
    IPR023214. HAD-like_dom.
    [Graphical view ]
    Pfami PF00690. Cation_ATPase_N. 1 hit.
    PF00122. E1-E2_ATPase. 1 hit.
    PF12409. P5-ATPase. 1 hit.
    [Graphical view ]
    PRINTSi PR00119. CATATPASE.
    SMARTi SM00831. Cation_ATPase_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56784. SSF56784. 3 hits.
    SSF81660. SSF81660. 1 hit.
    TIGRFAMsi TIGR01494. ATPase_P-type. 3 hits.
    TIGR01657. P-ATPase-V. 1 hit.
    PROSITEi PS00154. ATPASE_E1_E2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: CB.
      Tissue: Bursa of Fabricius.

    Entry informationi

    Entry nameiAT134_CHICK
    AccessioniPrimary (citable) accession number: Q5ZKB7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 26, 2008
    Last sequence update: November 23, 2004
    Last modified: October 1, 2014
    This is version 78 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3