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Q5ZJQ7

- SSU72_CHICK

UniProt

Q5ZJQ7 - SSU72_CHICK

Protein

RNA polymerase II subunit A C-terminal domain phosphatase SSU72

Gene

SSU72

Organism
Gallus gallus (Chicken)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 49 (01 Oct 2014)
      Sequence version 1 (23 Nov 2004)
      Previous versions | rss
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    Functioni

    May be involved in the C-terminal domain of RNA polymerase II dephosphorylation, RNA processing and termination.By similarity

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    GO - Molecular functioni

    1. CTD phosphatase activity Source: Ensembl

    GO - Biological processi

    1. dephosphorylation of RNA polymerase II C-terminal domain Source: Ensembl
    2. mRNA polyadenylation Source: Ensembl

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Biological processi

    mRNA processing

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    RNA polymerase II subunit A C-terminal domain phosphatase SSU72 (EC:3.1.3.16)
    Short name:
    CTD phosphatase SSU72
    Gene namesi
    Name:SSU72
    ORF Names:RCJMB04_16f24
    OrganismiGallus gallus (Chicken)
    Taxonomic identifieri9031 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus
    ProteomesiUP000000539: Chromosome 21

    Subcellular locationi

    Nucleus By similarity. Cytoplasm By similarity
    Note: Predominantly in the cytosol.By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm, Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 194194RNA polymerase II subunit A C-terminal domain phosphatase SSU72PRO_0000330015Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi9031.ENSGALP00000002256.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5ZJQ7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili160 – 18627Sequence AnalysisAdd
    BLAST

    Sequence similaritiesi

    Belongs to the SSU72 phosphatase family.Curated

    Keywords - Domaini

    Coiled coil

    Phylogenomic databases

    eggNOGiCOG5211.
    GeneTreeiENSGT00390000010165.
    HOGENOMiHOG000183445.
    HOVERGENiHBG059831.
    InParanoidiQ5ZJQ7.
    KOiK15544.
    OMAiNRPFLHT.
    OrthoDBiEOG7C2R2M.
    PhylomeDBiQ5ZJQ7.
    TreeFamiTF300194.

    Family and domain databases

    InterProiIPR006811. RNA_pol_II_suA.
    [Graphical view]
    PANTHERiPTHR20383. PTHR20383. 1 hit.
    PfamiPF04722. Ssu72. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5ZJQ7-1 [UniParc]FASTAAdd to Basket

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    MPSSPLRVAV VCSSNQNRSM EAHNILSKRG FSVRSFGTGT HVKLPGPAPD    50
    KPNVYDFKTT YDQMYNDLLR KDKELYTQNG ILHMLDRNKR IKPRPERFQN 100
    CKDVFDLILT CEERVYDQVV EDLNSREQET CQPVHVINVD IQDNHEEATL 150
    GAFLICELCQ CIQHTEDMEN EIDELLQEFE EKSGRTFLHT VCFY 194
    Length:194
    Mass (Da):22,574
    Last modified:November 23, 2004 - v1
    Checksum:i31C535EDA686306C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ720377 mRNA. Translation: CAG32036.1.
    RefSeqiNP_001007876.1. NM_001007875.1.
    UniGeneiGga.9388.

    Genome annotation databases

    EnsembliENSGALT00000002258; ENSGALP00000002256; ENSGALG00000001489.
    GeneIDi419410.
    KEGGigga:419410.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ720377 mRNA. Translation: CAG32036.1 .
    RefSeqi NP_001007876.1. NM_001007875.1.
    UniGenei Gga.9388.

    3D structure databases

    ProteinModelPortali Q5ZJQ7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9031.ENSGALP00000002256.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSGALT00000002258 ; ENSGALP00000002256 ; ENSGALG00000001489 .
    GeneIDi 419410.
    KEGGi gga:419410.

    Organism-specific databases

    CTDi 29101.

    Phylogenomic databases

    eggNOGi COG5211.
    GeneTreei ENSGT00390000010165.
    HOGENOMi HOG000183445.
    HOVERGENi HBG059831.
    InParanoidi Q5ZJQ7.
    KOi K15544.
    OMAi NRPFLHT.
    OrthoDBi EOG7C2R2M.
    PhylomeDBi Q5ZJQ7.
    TreeFami TF300194.

    Miscellaneous databases

    NextBioi 20822469.
    PROi Q5ZJQ7.

    Family and domain databases

    InterProi IPR006811. RNA_pol_II_suA.
    [Graphical view ]
    PANTHERi PTHR20383. PTHR20383. 1 hit.
    Pfami PF04722. Ssu72. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: CB.
      Tissue: Bursa of Fabricius.

    Entry informationi

    Entry nameiSSU72_CHICK
    AccessioniPrimary (citable) accession number: Q5ZJQ7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 29, 2008
    Last sequence update: November 23, 2004
    Last modified: October 1, 2014
    This is version 49 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3