Q5ZJQ7 (SSU72_CHICK) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
RNA polymerase II subunit A C-terminal domain phosphatase SSU72
Short name=CTD phosphatase SSU72
EC=3.1.3.16

Gene names

Name:	SSU72
ORF Names:	RCJMB04_16f24

Organism

Gallus gallus (Chicken) [Reference proteome]

Taxonomic identifier

9031 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Sauropsida › Sauria › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galliformes › Phasianidae › Phasianinae › Gallus

Protein attributes

Sequence length	194 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	May be involved in the C-terminal domain of RNA polymerase II dephosphorylation, RNA processing and termination By similarity.
Catalytic activity	A phosphoprotein + H2O = a protein + phosphate.
Subcellular location	Nucleus By similarity. Cytoplasm By similarity. Note: Predominantly in the cytosol By similarity.
Sequence similarities	Belongs to the SSU72 phosphatase family.

Ontologies

Keywords
Biological process	mRNA processing
Cellular component	Cytoplasm Nucleus
Domain	Coiled coil
Molecular function	Hydrolase Protein phosphatase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	mRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	phosphoprotein phosphatase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 194	194	RNA polymerase II subunit A C-terminal domain phosphatase SSU72		PRO_0000330015
Regions
	Coiled coil	160 – 186	27	Potential

Sequences

	Sequence		Length	Mass (Da)
	Q5ZJQ7 [UniParc]. Last modified November 23, 2004. Version 1. Checksum: 31C535EDA686306C	FASTA	194	22,574
	10 20 30 40 50 60 MPSSPLRVAV VCSSNQNRSM EAHNILSKRG FSVRSFGTGT HVKLPGPAPD KPNVYDFKTT 70 80 90 100 110 120 YDQMYNDLLR KDKELYTQNG ILHMLDRNKR IKPRPERFQN CKDVFDLILT CEERVYDQVV 130 140 150 160 170 180 EDLNSREQET CQPVHVINVD IQDNHEEATL GAFLICELCQ CIQHTEDMEN EIDELLQEFE 190 EKSGRTFLHT VCFY

References

[1]

"Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis." Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P., Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P., Hayashizaki Y., Buerstedde J.-M. Genome Biol. 6:R6.1-R6.9(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: CB. Tissue: Bursa of Fabricius.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ720377 mRNA. Translation: CAG32036.1.
IPI	IPI00577210.
RefSeq	NP_001007876.1. NM_001007875.1.
UniGene	Gga.9388.
3D structure databases
ProteinModelPortal	Q5ZJQ7.
ModBase	Search...
Protein-protein interaction databases
STRING	9031.ENSGALP00000002256.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSGALT00000002258; ENSGALP00000002256; ENSGALG00000001489.
GeneID	419410.
KEGG	gga:419410.
Organism-specific databases
CTD	29101.
Phylogenomic databases
eggNOG	COG5211.
GeneTree	ENSGT00390000010165.
HOGENOM	HOG000183445.
HOVERGEN	HBG059831.
InParanoid	Q5ZJQ7.
KO	K15544.
OMA	SMEAHNF.
OrthoDB	EOG49PB0D.
Family and domain databases
InterPro	IPR006811. RNA_pol_II_suA. [Graphical view]
PANTHER	PTHR20383. PTHR20383. 1 hit.
Pfam	PF04722. Ssu72. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	20822469.

Entry information

Entry name

SSU72_CHICK

Accession

Primary (citable) accession number: Q5ZJQ7

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 29, 2008
Last sequence update:	November 23, 2004
Last modified:	April 3, 2013
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program