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Q5ZJJ8

- UBCP1_CHICK

UniProt

Q5ZJJ8 - UBCP1_CHICK

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Protein

Ubiquitin-like domain-containing CTD phosphatase 1

Gene

UBLCP1

Organism
Gallus gallus (Chicken)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome By similarity.By similarity

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Magnesium.By similarity

GO - Molecular functioni

  1. phosphoprotein phosphatase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquitin-like domain-containing CTD phosphatase 1 (EC:3.1.3.16)
Alternative name(s):
Nuclear proteasome inhibitor UBLCP1
Gene namesi
Name:UBLCP1
ORF Names:RCJMB04_17j14
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus
ProteomesiUP000000539: Chromosome 13

Subcellular locationi

Nucleus By similarity
Note: Colocalizes with nuclear proteasomes.By similarity

GO - Cellular componenti

  1. nucleolus Source: Ensembl
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 318318Ubiquitin-like domain-containing CTD phosphatase 1PRO_0000242644Add
BLAST

Proteomic databases

PaxDbiQ5ZJJ8.
PRIDEiQ5ZJJ8.

Structurei

3D structure databases

ProteinModelPortaliQ5ZJJ8.
SMRiQ5ZJJ8. Positions 3-79.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini3 – 8179Ubiquitin-likePROSITE-ProRule annotationAdd
BLAST
Domaini133 – 294162FCP1 homologyPROSITE-ProRule annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni133 – 294162PhosphataseBy similarityAdd
BLAST

Domaini

The Ubiquitin-like domain mediates interaction with proteasomes.By similarity

Sequence similaritiesi

Contains 1 FCP1 homology domain.PROSITE-ProRule annotation
Contains 1 ubiquitin-like domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiNOG310886.
GeneTreeiENSGT00390000010107.
HOGENOMiHOG000231279.
HOVERGENiHBG080207.
InParanoidiQ5ZJJ8.
KOiK17618.
OMAiELNPPRE.
OrthoDBiEOG74TX01.
PhylomeDBiQ5ZJJ8.
TreeFamiTF323786.

Family and domain databases

Gene3Di3.40.50.1000. 1 hit.
InterProiIPR023214. HAD-like_dom.
IPR011943. HAD-SF_hydro_IIID.
IPR004274. NIF.
IPR000626. Ubiquitin-like.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PfamiPF03031. NIF. 1 hit.
PF00240. ubiquitin. 1 hit.
[Graphical view]
SMARTiSM00577. CPDc. 1 hit.
SM00213. UBQ. 1 hit.
[Graphical view]
SUPFAMiSSF54236. SSF54236. 1 hit.
SSF56784. SSF56784. 1 hit.
TIGRFAMsiTIGR02245. HAD_IIID1. 1 hit.
PROSITEiPS50969. FCP1. 1 hit.
PS50053. UBIQUITIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5ZJJ8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSLSLIIKWG GQEYTITSLS EEDTVLDLKQ SLKGLTGVLP ERQKLLGLKM
60 70 80 90 100
KGKPADDDVK LGALKLKPNT KIMMMGTREE SLEDVLGPPP DNDDVINDFD
110 120 130 140 150
IEEEVVEVEN REENLLKISR RVKEYKVEIL NPPREGKKLL VLDVDYTLFD
160 170 180 190 200
HRSCAETGVE LMRPYLHEFL TSAYEDYDIV IWSATNMKWI EAKMKELGVS
210 220 230 240 250
TNANYKITFM LDSAAMITVH TPRRGLIDVK PLGVIWGKFS EYYSKKNTIM
260 270 280 290 300
FDDIGRNFLM NPQNGLKIRP FMKAHLNRDK DKELLKLTQY LKEIAKLDDF
310
LELNHKHWER YLSKKQGQ
Length:318
Mass (Da):36,800
Last modified:November 23, 2004 - v1
Checksum:iFC73F52A7B36668C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ720436 mRNA. Translation: CAG32095.1.
RefSeqiNP_001025784.2. NM_001030613.3.
UniGeneiGga.22390.

Genome annotation databases

EnsembliENSGALT00000005818; ENSGALP00000005808; ENSGALG00000003672.
ENSGALT00000045795; ENSGALP00000040691; ENSGALG00000003672.
GeneIDi416237.
KEGGigga:416237.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ720436 mRNA. Translation: CAG32095.1 .
RefSeqi NP_001025784.2. NM_001030613.3.
UniGenei Gga.22390.

3D structure databases

ProteinModelPortali Q5ZJJ8.
SMRi Q5ZJJ8. Positions 3-79.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PaxDbi Q5ZJJ8.
PRIDEi Q5ZJJ8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSGALT00000005818 ; ENSGALP00000005808 ; ENSGALG00000003672 .
ENSGALT00000045795 ; ENSGALP00000040691 ; ENSGALG00000003672 .
GeneIDi 416237.
KEGGi gga:416237.

Organism-specific databases

CTDi 134510.

Phylogenomic databases

eggNOGi NOG310886.
GeneTreei ENSGT00390000010107.
HOGENOMi HOG000231279.
HOVERGENi HBG080207.
InParanoidi Q5ZJJ8.
KOi K17618.
OMAi ELNPPRE.
OrthoDBi EOG74TX01.
PhylomeDBi Q5ZJJ8.
TreeFami TF323786.

Miscellaneous databases

NextBioi 20819726.
PROi Q5ZJJ8.

Family and domain databases

Gene3Di 3.40.50.1000. 1 hit.
InterProi IPR023214. HAD-like_dom.
IPR011943. HAD-SF_hydro_IIID.
IPR004274. NIF.
IPR000626. Ubiquitin-like.
IPR029071. Ubiquitin-rel_dom.
[Graphical view ]
Pfami PF03031. NIF. 1 hit.
PF00240. ubiquitin. 1 hit.
[Graphical view ]
SMARTi SM00577. CPDc. 1 hit.
SM00213. UBQ. 1 hit.
[Graphical view ]
SUPFAMi SSF54236. SSF54236. 1 hit.
SSF56784. SSF56784. 1 hit.
TIGRFAMsi TIGR02245. HAD_IIID1. 1 hit.
PROSITEi PS50969. FCP1. 1 hit.
PS50053. UBIQUITIN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: CB.
    Tissue: Bursa of Fabricius.

Entry informationi

Entry nameiUBCP1_CHICK
AccessioniPrimary (citable) accession number: Q5ZJJ8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: November 23, 2004
Last modified: October 1, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3