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Q5ZJJ8

- UBCP1_CHICK

UniProt

Q5ZJJ8 - UBCP1_CHICK

Protein

Ubiquitin-like domain-containing CTD phosphatase 1

Gene

UBLCP1

Organism
Gallus gallus (Chicken)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 66 (01 Oct 2014)
      Sequence version 1 (23 Nov 2004)
      Previous versions | rss
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    Functioni

    Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome By similarity.By similarity

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Magnesium.By similarity

    GO - Molecular functioni

    1. phosphoprotein phosphatase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ubiquitin-like domain-containing CTD phosphatase 1 (EC:3.1.3.16)
    Alternative name(s):
    Nuclear proteasome inhibitor UBLCP1
    Gene namesi
    Name:UBLCP1
    ORF Names:RCJMB04_17j14
    OrganismiGallus gallus (Chicken)
    Taxonomic identifieri9031 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus
    ProteomesiUP000000539: Chromosome 13

    Subcellular locationi

    Nucleus By similarity
    Note: Colocalizes with nuclear proteasomes.By similarity

    GO - Cellular componenti

    1. nucleolus Source: Ensembl

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 318318Ubiquitin-like domain-containing CTD phosphatase 1PRO_0000242644Add
    BLAST

    Proteomic databases

    PaxDbiQ5ZJJ8.
    PRIDEiQ5ZJJ8.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5ZJJ8.
    SMRiQ5ZJJ8. Positions 3-79.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini3 – 8179Ubiquitin-likePROSITE-ProRule annotationAdd
    BLAST
    Domaini133 – 294162FCP1 homologyPROSITE-ProRule annotationAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni133 – 294162PhosphataseBy similarityAdd
    BLAST

    Domaini

    The Ubiquitin-like domain mediates interaction with proteasomes.By similarity

    Sequence similaritiesi

    Contains 1 FCP1 homology domain.PROSITE-ProRule annotation
    Contains 1 ubiquitin-like domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiNOG310886.
    GeneTreeiENSGT00390000010107.
    HOGENOMiHOG000231279.
    HOVERGENiHBG080207.
    InParanoidiQ5ZJJ8.
    KOiK17618.
    OMAiELNPPRE.
    OrthoDBiEOG74TX01.
    PhylomeDBiQ5ZJJ8.
    TreeFamiTF323786.

    Family and domain databases

    Gene3Di3.40.50.1000. 1 hit.
    InterProiIPR023214. HAD-like_dom.
    IPR011943. HAD-SF_hydro_IIID.
    IPR004274. NIF.
    IPR000626. Ubiquitin-like.
    IPR029071. Ubiquitin-rel_dom.
    [Graphical view]
    PfamiPF03031. NIF. 1 hit.
    PF00240. ubiquitin. 1 hit.
    [Graphical view]
    SMARTiSM00577. CPDc. 1 hit.
    SM00213. UBQ. 1 hit.
    [Graphical view]
    SUPFAMiSSF54236. SSF54236. 1 hit.
    SSF56784. SSF56784. 1 hit.
    TIGRFAMsiTIGR02245. HAD_IIID1. 1 hit.
    PROSITEiPS50969. FCP1. 1 hit.
    PS50053. UBIQUITIN_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5ZJJ8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSLSLIIKWG GQEYTITSLS EEDTVLDLKQ SLKGLTGVLP ERQKLLGLKM    50
    KGKPADDDVK LGALKLKPNT KIMMMGTREE SLEDVLGPPP DNDDVINDFD 100
    IEEEVVEVEN REENLLKISR RVKEYKVEIL NPPREGKKLL VLDVDYTLFD 150
    HRSCAETGVE LMRPYLHEFL TSAYEDYDIV IWSATNMKWI EAKMKELGVS 200
    TNANYKITFM LDSAAMITVH TPRRGLIDVK PLGVIWGKFS EYYSKKNTIM 250
    FDDIGRNFLM NPQNGLKIRP FMKAHLNRDK DKELLKLTQY LKEIAKLDDF 300
    LELNHKHWER YLSKKQGQ 318
    Length:318
    Mass (Da):36,800
    Last modified:November 23, 2004 - v1
    Checksum:iFC73F52A7B36668C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ720436 mRNA. Translation: CAG32095.1.
    RefSeqiNP_001025784.2. NM_001030613.3.
    UniGeneiGga.22390.

    Genome annotation databases

    EnsembliENSGALT00000005818; ENSGALP00000005808; ENSGALG00000003672.
    ENSGALT00000045795; ENSGALP00000040691; ENSGALG00000003672.
    GeneIDi416237.
    KEGGigga:416237.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ720436 mRNA. Translation: CAG32095.1 .
    RefSeqi NP_001025784.2. NM_001030613.3.
    UniGenei Gga.22390.

    3D structure databases

    ProteinModelPortali Q5ZJJ8.
    SMRi Q5ZJJ8. Positions 3-79.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PaxDbi Q5ZJJ8.
    PRIDEi Q5ZJJ8.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSGALT00000005818 ; ENSGALP00000005808 ; ENSGALG00000003672 .
    ENSGALT00000045795 ; ENSGALP00000040691 ; ENSGALG00000003672 .
    GeneIDi 416237.
    KEGGi gga:416237.

    Organism-specific databases

    CTDi 134510.

    Phylogenomic databases

    eggNOGi NOG310886.
    GeneTreei ENSGT00390000010107.
    HOGENOMi HOG000231279.
    HOVERGENi HBG080207.
    InParanoidi Q5ZJJ8.
    KOi K17618.
    OMAi ELNPPRE.
    OrthoDBi EOG74TX01.
    PhylomeDBi Q5ZJJ8.
    TreeFami TF323786.

    Miscellaneous databases

    NextBioi 20819726.
    PROi Q5ZJJ8.

    Family and domain databases

    Gene3Di 3.40.50.1000. 1 hit.
    InterProi IPR023214. HAD-like_dom.
    IPR011943. HAD-SF_hydro_IIID.
    IPR004274. NIF.
    IPR000626. Ubiquitin-like.
    IPR029071. Ubiquitin-rel_dom.
    [Graphical view ]
    Pfami PF03031. NIF. 1 hit.
    PF00240. ubiquitin. 1 hit.
    [Graphical view ]
    SMARTi SM00577. CPDc. 1 hit.
    SM00213. UBQ. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54236. SSF54236. 1 hit.
    SSF56784. SSF56784. 1 hit.
    TIGRFAMsi TIGR02245. HAD_IIID1. 1 hit.
    PROSITEi PS50969. FCP1. 1 hit.
    PS50053. UBIQUITIN_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: CB.
      Tissue: Bursa of Fabricius.

    Entry informationi

    Entry nameiUBCP1_CHICK
    AccessioniPrimary (citable) accession number: Q5ZJJ8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 27, 2006
    Last sequence update: November 23, 2004
    Last modified: October 1, 2014
    This is version 66 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3