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Protein

Phosphatidylinositol 4-phosphate 5-kinase type-1 beta

Gene

PIP5K1B

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. Mediates reorganization of actin filaments (By similarity).By similarity

Catalytic activityi

ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphatidylinositol 4-phosphate 5-kinase type-1 beta (EC:2.7.1.68)
Short name:
PIP5K1-beta
Short name:
PtdIns(4)P-5-kinase 1 beta
Alternative name(s):
Phosphatidylinositol 4-phosphate 5-kinase type I beta
Short name:
PIP5KIbeta
Type I phosphatidylinositol 4-phosphate 5-kinase beta
Gene namesi
Name:PIP5K1B
ORF Names:RCJMB04_20j15
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Unplaced

Subcellular locationi

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001854611 – 540Phosphatidylinositol 4-phosphate 5-kinase type-1 betaAdd BLAST540

Proteomic databases

PaxDbiQ5ZJ58

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000037435

Structurei

3D structure databases

ProteinModelPortaliQ5ZJ58
SMRiQ5ZJ58
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 395PIPKPROSITE-ProRule annotationAdd BLAST371

Phylogenomic databases

eggNOGiKOG0229 Eukaryota
COG5253 LUCA
HOGENOMiHOG000193876
HOVERGENiHBG052818
InParanoidiQ5ZJ58
KOiK00889
PhylomeDBiQ5ZJ58

Family and domain databases

Gene3Di3.30.800.10, 1 hit
3.30.810.10, 2 hits
InterProiView protein in InterPro
IPR023610 PInositol-4-P-5-kinase
IPR027483 PInositol-4-P-5-kinase_C
IPR002498 PInositol-4-P-5-kinase_core
IPR027484 PInositol-4-P-5-kinase_N
PANTHERiPTHR23086 PTHR23086, 1 hit
PfamiView protein in Pfam
PF01504 PIP5K, 1 hit
SMARTiView protein in SMART
SM00330 PIPKc, 1 hit
PROSITEiView protein in PROSITE
PS51455 PIPK, 1 hit

Sequencei

Sequence statusi: Complete.

Q5ZJ58-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSVTENGDV TAGKPNEEKT YKKTTSSAIK GAIQLGIGYT VGNLTSKPDR
60 70 80 90 100
DVLMQDFYVV ESVFLPSEGS NLTPAHHYPD FRFKTYAPLA FRYFRELFGI
110 120 130 140 150
KPDDYLYSIC SEPLIELSNP GASGSLFFVT SDDEFIIKTV QHKEAEFLQK
160 170 180 190 200
LLPGYYMNLN QNPRTLLPKF YGLYCVQSGG INIRIVVMNN VLPRALKMNF
210 220 230 240 250
TYDLKGSTYK RRASRKEREK SNPTFKDLDF LQDMHEGLYF DSETHSALMK
260 270 280 290 300
TLQRDCRVLE SFKIMDYSLL LGIHVLNSNV REKEGESSQN ASDGKRPGGQ
310 320 330 340 350
KVLYSTAMES IQGPGKSGDS VVTETTNTMG GIPAKSHKGE KLLLFMGIID
360 370 380 390 400
ILQSYRLMKK LEHSWKALVY DGDTVSVHRP SFYADRFLKF MNTRVFKKVQ
410 420 430 440 450
ALRSSPSKKR CNSITALKAT SQEIVSAVSQ EWKDEKHSII TEGQSYSSLD
460 470 480 490 500
EEVLGSRRRP DLVPSTPSLF EAASLATTVS SSSLNVDERY QRDQTMLYSS
510 520 530 540
SKELPSSSTF TLEDSAIYLT SEQSTLETEN DNASVLDVYL
Length:540
Mass (Da):60,719
Last modified:November 23, 2004 - v1
Checksum:i5F9720849533D784
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ720576 mRNA Translation: CAG32235.1
RefSeqiNP_001026593.1, NM_001031422.1
UniGeneiGga.17037

Genome annotation databases

GeneIDi427243
KEGGigga:427243

Similar proteinsi

Entry informationi

Entry nameiPI51B_CHICK
AccessioniPrimary (citable) accession number: Q5ZJ58
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: November 23, 2004
Last modified: February 28, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health