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Q5ZJ58

- PI51B_CHICK

UniProt

Q5ZJ58 - PI51B_CHICK

Protein

Phosphatidylinositol 4-phosphate 5-kinase type-1 beta

Gene

PIP5K1B

Organism
Gallus gallus (Chicken)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 65 (01 Oct 2014)
      Sequence version 1 (23 Nov 2004)
      Previous versions | rss
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    Functioni

    Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. Mediates reorganization of actin filaments By similarity.By similarity

    Catalytic activityi

    ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.

    GO - Molecular functioni

    1. 1-phosphatidylinositol-4-phosphate 5-kinase activity Source: UniProtKB-EC
    2. ATP binding Source: UniProtKB-KW

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphatidylinositol 4-phosphate 5-kinase type-1 beta (EC:2.7.1.68)
    Short name:
    PIP5K1-beta
    Short name:
    PtdIns(4)P-5-kinase 1 beta
    Alternative name(s):
    Phosphatidylinositol 4-phosphate 5-kinase type I beta
    Short name:
    PIP5KIbeta
    Type I phosphatidylinositol 4-phosphate 5-kinase beta
    Gene namesi
    Name:PIP5K1B
    ORF Names:RCJMB04_20j15
    OrganismiGallus gallus (Chicken)
    Taxonomic identifieri9031 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus
    ProteomesiUP000000539: Unplaced

    Subcellular locationi

    Endomembrane system By similarity
    Note: Associated with membranes.By similarity

    GO - Cellular componenti

    1. endomembrane system Source: UniProtKB-SubCell
    2. membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 540540Phosphatidylinositol 4-phosphate 5-kinase type-1 betaPRO_0000185461Add
    BLAST

    Proteomic databases

    PaxDbiQ5ZJ58.

    Interactioni

    Protein-protein interaction databases

    STRINGi9031.ENSGALP00000037435.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5ZJ58.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini25 – 395371PIPKPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 PIPK domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG5253.
    HOGENOMiHOG000193876.
    HOVERGENiHBG052818.
    InParanoidiQ5ZJ58.
    KOiK00889.
    PhylomeDBiQ5ZJ58.

    Family and domain databases

    Gene3Di3.30.800.10. 1 hit.
    3.30.810.10. 1 hit.
    InterProiIPR023610. PInositol-4-P-5-kinase.
    IPR027483. PInositol-4-P-5-kinase_C.
    IPR002498. PInositol-4-P-5-kinase_core.
    IPR027484. PInositol-4-P-5-kinase_N.
    IPR016034. PInositol-4P-5-kinase_core_sub.
    [Graphical view]
    PANTHERiPTHR23086. PTHR23086. 1 hit.
    PfamiPF01504. PIP5K. 1 hit.
    [Graphical view]
    SMARTiSM00330. PIPKc. 1 hit.
    [Graphical view]
    PROSITEiPS51455. PIPK. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5ZJ58-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSSVTENGDV TAGKPNEEKT YKKTTSSAIK GAIQLGIGYT VGNLTSKPDR    50
    DVLMQDFYVV ESVFLPSEGS NLTPAHHYPD FRFKTYAPLA FRYFRELFGI 100
    KPDDYLYSIC SEPLIELSNP GASGSLFFVT SDDEFIIKTV QHKEAEFLQK 150
    LLPGYYMNLN QNPRTLLPKF YGLYCVQSGG INIRIVVMNN VLPRALKMNF 200
    TYDLKGSTYK RRASRKEREK SNPTFKDLDF LQDMHEGLYF DSETHSALMK 250
    TLQRDCRVLE SFKIMDYSLL LGIHVLNSNV REKEGESSQN ASDGKRPGGQ 300
    KVLYSTAMES IQGPGKSGDS VVTETTNTMG GIPAKSHKGE KLLLFMGIID 350
    ILQSYRLMKK LEHSWKALVY DGDTVSVHRP SFYADRFLKF MNTRVFKKVQ 400
    ALRSSPSKKR CNSITALKAT SQEIVSAVSQ EWKDEKHSII TEGQSYSSLD 450
    EEVLGSRRRP DLVPSTPSLF EAASLATTVS SSSLNVDERY QRDQTMLYSS 500
    SKELPSSSTF TLEDSAIYLT SEQSTLETEN DNASVLDVYL 540
    Length:540
    Mass (Da):60,719
    Last modified:November 23, 2004 - v1
    Checksum:i5F9720849533D784
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ720576 mRNA. Translation: CAG32235.1.
    RefSeqiNP_001026593.1. NM_001031422.1.
    UniGeneiGga.17037.

    Genome annotation databases

    GeneIDi427243.
    KEGGigga:427243.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ720576 mRNA. Translation: CAG32235.1 .
    RefSeqi NP_001026593.1. NM_001031422.1.
    UniGenei Gga.17037.

    3D structure databases

    ProteinModelPortali Q5ZJ58.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9031.ENSGALP00000037435.

    Proteomic databases

    PaxDbi Q5ZJ58.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 427243.
    KEGGi gga:427243.

    Organism-specific databases

    CTDi 8395.

    Phylogenomic databases

    eggNOGi COG5253.
    HOGENOMi HOG000193876.
    HOVERGENi HBG052818.
    InParanoidi Q5ZJ58.
    KOi K00889.
    PhylomeDBi Q5ZJ58.

    Miscellaneous databases

    NextBioi 20828532.
    PROi Q5ZJ58.

    Family and domain databases

    Gene3Di 3.30.800.10. 1 hit.
    3.30.810.10. 1 hit.
    InterProi IPR023610. PInositol-4-P-5-kinase.
    IPR027483. PInositol-4-P-5-kinase_C.
    IPR002498. PInositol-4-P-5-kinase_core.
    IPR027484. PInositol-4-P-5-kinase_N.
    IPR016034. PInositol-4P-5-kinase_core_sub.
    [Graphical view ]
    PANTHERi PTHR23086. PTHR23086. 1 hit.
    Pfami PF01504. PIP5K. 1 hit.
    [Graphical view ]
    SMARTi SM00330. PIPKc. 1 hit.
    [Graphical view ]
    PROSITEi PS51455. PIPK. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: CB.
      Tissue: Bursa of Fabricius.

    Entry informationi

    Entry nameiPI51B_CHICK
    AccessioniPrimary (citable) accession number: Q5ZJ58
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 25, 2005
    Last sequence update: November 23, 2004
    Last modified: October 1, 2014
    This is version 65 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3