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Protein

Density-regulated protein

Gene

DENR

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitment of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Density-regulated protein
Short name:
DRP
Gene namesi
Name:DENR
ORF Names:RCJMB04_20p1
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Unplaced

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001306031 – 198Density-regulated proteinAdd BLAST198

Proteomic databases

PaxDbiQ5ZJ39.
PRIDEiQ5ZJ39.

Expressioni

Gene expression databases

BgeeiENSGALG00000003795.

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000006010.

Structurei

3D structure databases

ProteinModelPortaliQ5ZJ39.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini115 – 182SUI1PROSITE-ProRule annotationAdd BLAST68

Sequence similaritiesi

Belongs to the DENR family.Curated
Contains 1 SUI1 domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG3239. Eukaryota.
COG0023. LUCA.
GeneTreeiENSGT00390000014349.
HOGENOMiHOG000237611.
HOVERGENiHBG005471.
InParanoidiQ5ZJ39.
OrthoDBiEOG091G0R9X.
PhylomeDBiQ5ZJ39.

Family and domain databases

Gene3Di3.30.780.10. 1 hit.
InterProiIPR005873. Drp1.
IPR001950. SUI1.
[Graphical view]
PfamiPF01253. SUI1. 1 hit.
[Graphical view]
SUPFAMiSSF55159. SSF55159. 2 hits.
TIGRFAMsiTIGR01159. DRP1. 1 hit.
PROSITEiPS50296. SUI1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5ZJ39-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATDVAEPVV PDCRGDIRSG ARSDADYPLR VLYCGVCSLP TEYCEYMPDV
60 70 80 90 100
TKCRQWLEKN FPDEFAKLTV ENSPKQEAGV GEGQGTAGEE EEKKKQKRGG
110 120 130 140 150
RGQIKQKKKT VPQKVTIAKI PRAKKKYVTR VCGLATFEID LKEAQRFFAQ
160 170 180 190
KFSCGASVTG EDEIIIQGDF TDDIIDVIQE KWPEVDDDSI EDLGEVKK
Length:198
Mass (Da):22,158
Last modified:November 23, 2004 - v1
Checksum:i2A43A2FF5D6EC9C4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ720595 mRNA. Translation: CAG32254.1.
RefSeqiNP_001072973.1. NM_001079505.1.
UniGeneiGga.8483.

Genome annotation databases

EnsembliENSGALT00000034620; ENSGALP00000033977; ENSGALG00000003795.
GeneIDi771794.
KEGGigga:771794.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ720595 mRNA. Translation: CAG32254.1.
RefSeqiNP_001072973.1. NM_001079505.1.
UniGeneiGga.8483.

3D structure databases

ProteinModelPortaliQ5ZJ39.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000006010.

Proteomic databases

PaxDbiQ5ZJ39.
PRIDEiQ5ZJ39.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSGALT00000034620; ENSGALP00000033977; ENSGALG00000003795.
GeneIDi771794.
KEGGigga:771794.

Organism-specific databases

CTDi8562.

Phylogenomic databases

eggNOGiKOG3239. Eukaryota.
COG0023. LUCA.
GeneTreeiENSGT00390000014349.
HOGENOMiHOG000237611.
HOVERGENiHBG005471.
InParanoidiQ5ZJ39.
OrthoDBiEOG091G0R9X.
PhylomeDBiQ5ZJ39.

Miscellaneous databases

PROiQ5ZJ39.

Gene expression databases

BgeeiENSGALG00000003795.

Family and domain databases

Gene3Di3.30.780.10. 1 hit.
InterProiIPR005873. Drp1.
IPR001950. SUI1.
[Graphical view]
PfamiPF01253. SUI1. 1 hit.
[Graphical view]
SUPFAMiSSF55159. SSF55159. 2 hits.
TIGRFAMsiTIGR01159. DRP1. 1 hit.
PROSITEiPS50296. SUI1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDENR_CHICK
AccessioniPrimary (citable) accession number: Q5ZJ39
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 24, 2006
Last sequence update: November 23, 2004
Last modified: November 30, 2016
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.