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Q5ZJ23 (ASSY_CHICK) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Argininosuccinate synthase

EC=6.3.4.5
Alternative name(s):
Citrulline--aspartate ligase
Gene names
Name:ASS1
ORF Names:RCJMB04_21j5
OrganismGallus gallus (Chicken) [Reference proteome]
Taxonomic identifier9031 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus

Protein attributes

Sequence length416 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 416416Argininosuccinate synthase HAMAP-Rule MF_00005
PRO_0000321322

Regions

Nucleotide binding11 – 199ATP By similarity
Nucleotide binding116 – 1249ATP By similarity

Sites

Binding site371ATP; via amide nitrogen and carbonyl oxygen By similarity
Binding site881Citrulline By similarity
Binding site1201Aspartate By similarity
Binding site1241Aspartate By similarity
Binding site1241Citrulline By similarity
Binding site1251Aspartate By similarity
Binding site1281Citrulline By similarity
Binding site1811Citrulline By similarity
Binding site1901Citrulline By similarity
Binding site2711Citrulline By similarity
Binding site2831Citrulline By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5ZJ23 [UniParc].

Last modified November 23, 2004. Version 1.
Checksum: AF0CC73CA67D1B71

FASTA41646,904
        10         20         30         40         50         60 
MAEPRDTVVL AYSGGLDTSC ILVWLKEQGY TVIAFLANIG QTEDFDAAQK KALALGAKKV 

        70         80         90        100        110        120 
YIQDVCREFV EDFIWPAVRA NALYEDRYML GSALARPCIA RHLVLIAQEE GARYIAHGAT 

       130        140        150        160        170        180 
GKGNDQVRFE LGCYALCPSI KVIAPWRMPE FYQRFPGRRE LMEYAQKHGI PVPVTPKAPW 

       190        200        210        220        230        240 
SMDENLMHIS YEAGILENPK NRAPLDLYTK TCNPTTSPDV PDELEIEFEK GVPVKVTNTR 

       250        260        270        280        290        300 
NGVTHRSALE LFVYLNDIAS KHGVGRVDIV ENRFVGMKSR GIYETPAGTI LYHAHLDIEA 

       310        320        330        340        350        360 
FTMDREVRKI KQGLSLKFSE LVYNGFWYSP ECEFLKHCIA RSQQAVAGTV HVSVFKGQVY 

       370        380        390        400        410 
VLGRESPHSL YNEELVSMDV QGDYEPADAT GFININALRL KEYHRLQSKV STKQDE 

« Hide

References

[1]"Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis."
Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P., Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P., Hayashizaki Y., Buerstedde J.-M.
Genome Biol. 6:R6.1-R6.9(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: CB.
Tissue: Bursa of Fabricius.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ720611 mRNA. Translation: CAG32270.1.
RefSeqNP_001013413.1. NM_001013395.1.
UniGeneGga.5385.

3D structure databases

ProteinModelPortalQ5ZJ23.
SMRQ5ZJ23. Positions 5-408.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING9031.ENSGALP00000006379.

Proteomic databases

PaxDbQ5ZJ23.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID417185.
KEGGgga:417185.

Organism-specific databases

CTD445.

Phylogenomic databases

eggNOGCOG0137.
HOGENOMHOG000230093.
HOVERGENHBG001717.
InParanoidQ5ZJ23.
KOK01940.
PhylomeDBQ5ZJ23.

Enzyme and pathway databases

UniPathwayUPA00068; UER00113.
UPA00158; UER00272.

Family and domain databases

Gene3D3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPMF_00005. Arg_succ_synth_type1.
InterProIPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamPF00764. Arginosuc_synth. 1 hit.
[Graphical view]
TIGRFAMsTIGR00032. argG. 1 hit.
PROSITEPS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20820530.
PROQ5ZJ23.

Entry information

Entry nameASSY_CHICK
AccessionPrimary (citable) accession number: Q5ZJ23
Entry history
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: November 23, 2004
Last modified: April 16, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways