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Q5ZIP6 (OTU6B_CHICK) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
OTU domain-containing protein 6B

EC=3.4.19.12
Gene names
Name:OTUD6B
ORF Names:RCJMB04_24h18
OrganismGallus gallus (Chicken) [Reference proteome]
Taxonomic identifier9031 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus

Protein attributes

Sequence length302 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).

Sequence similarities

Contains 1 OTU domain.

Ontologies

Keywords
   Biological processUbl conjugation pathway
   Molecular functionHydrolase
Protease
Thiol protease
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processproteolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functioncysteine-type peptidase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 302302OTU domain-containing protein 6B
PRO_0000076281

Regions

Domain156 – 293138OTU
Region161 – 1677Cys-loop By similarity
Region228 – 23811Variable-loop By similarity
Region276 – 28611His-loop By similarity

Sites

Active site1641 By similarity
Active site1671Nucleophile By similarity
Active site2861 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5ZIP6 [UniParc].

Last modified November 23, 2004. Version 1.
Checksum: D23A118D9F4A6A13

FASTA30234,542
        10         20         30         40         50         60 
MEGSEDEEAE AGGPLQQLVK RQRREKRELQ AKIQGMKNAV PKNDKKRRKQ LAEEVAKLEA 

        70         80         90        100        110        120 
ELEQKHKEEL KQLKEAMPEQ NKIDSIADGV ANFELEGREQ QIQHPRISKA QKRREKKAAL 

       130        140        150        160        170        180 
EKEREERIAE AEIENLTGAR HLESQKLASL LAARHLEIKQ IPSDGHCMYR AIEDQLKDHH 

       190        200        210        220        230        240 
NSWTVATLRN QTAKYIHSHF DDFLPFLTNP NTGDMYSKEE FEKYCDDIAN TAAWGGQLEL 

       250        260        270        280        290        300 
RALSHILQTP IEVVQMDSPS IIVGEEYSGK PIILVYMRHA YGLGEHYNSV KLLTDATTEN 


GS 

« Hide

References

[1]"Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis."
Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P., Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P., Hayashizaki Y., Buerstedde J.-M.
Genome Biol. 6:R6.1-R6.9(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: CB.
Tissue: Bursa of Fabricius.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ720738 mRNA. Translation: CAG32397.1.
RefSeqNP_001006347.1. NM_001006347.1.
UniGeneGga.16131.

3D structure databases

ProteinModelPortalQ5ZIP6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING9031.ENSGALP00000025612.

Proteomic databases

PaxDbQ5ZIP6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSGALT00000025659; ENSGALP00000025612; ENSGALG00000015920.
GeneID420222.
KEGGgga:420222.

Organism-specific databases

CTD51633.

Phylogenomic databases

eggNOGCOG5539.
GeneTreeENSGT00390000012840.
HOGENOMHOG000192906.
HOVERGENHBG080227.
InParanoidQ5ZIP6.
OMADMYTPEE.
OrthoDBEOG7WT42W.
PhylomeDBQ5ZIP6.
TreeFamTF315010.

Family and domain databases

InterProIPR003323. OTU.
[Graphical view]
PfamPF02338. OTU. 1 hit.
[Graphical view]
PROSITEPS50802. OTU. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20823170.
PROQ5ZIP6.

Entry information

Entry nameOTU6B_CHICK
AccessionPrimary (citable) accession number: Q5ZIP6
Entry history
Integrated into UniProtKB/Swiss-Prot: January 24, 2006
Last sequence update: November 23, 2004
Last modified: April 16, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families