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Protein

Solute carrier family 25 member 46

Gene

SLC25A46

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May play a role in mitochondrial dynamics by controlling mitochondrial membrane fission.By similarity

GO - Biological processi

Keywordsi

Biological processTransport

Names & Taxonomyi

Protein namesi
Recommended name:
Solute carrier family 25 member 46
Gene namesi
Name:SLC25A46
ORF Names:RCJMB04_26i24
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome Z

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei93 – 113Helical; Name=1Sequence analysisAdd BLAST21
Transmembranei157 – 177Helical; Name=2Sequence analysisAdd BLAST21
Transmembranei189 – 209Helical; Name=3Sequence analysisAdd BLAST21
Transmembranei248 – 268Helical; Name=4Sequence analysisAdd BLAST21
Transmembranei304 – 324Helical; Name=5Sequence analysisAdd BLAST21
Transmembranei373 – 393Helical; Name=6Sequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion outer membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002918311 – 408Solute carrier family 25 member 46Add BLAST408

Proteomic databases

PaxDbiQ5ZIG3.

Expressioni

Gene expression databases

BgeeiENSGALG00000000253.

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000000331.

Structurei

3D structure databases

ProteinModelPortaliQ5ZIG3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati86 – 177Solcar 1Add BLAST92
Repeati301 – 403Solcar 2Add BLAST103

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG2954. Eukaryota.
ENOG410XRFB. LUCA.
GeneTreeiENSGT00390000015874.
HOGENOMiHOG000007981.
HOVERGENiHBG059752.
InParanoidiQ5ZIG3.
KOiK03454.
OMAiEISHKWN.
OrthoDBiEOG091G05RA.
PhylomeDBiQ5ZIG3.
TreeFamiTF313365.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiView protein in InterPro
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
PfamiView protein in Pfam
PF00153. Mito_carr. 2 hits.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiView protein in PROSITE
PS50920. SOLCAR. 2 hits.

Sequencei

Sequence statusi: Complete.

Q5ZIG3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHPRRPEGFD GLGYRGGGRE EPCPGVRPFG GGAEMGHWVT TPPDIPGSRN
60 70 80 90 100
LHWGEKTPPY GAGTPLGAAG LNEEPGLGAG GPGAEQLNRF AGFGIGLASL
110 120 130 140 150
FTENVLAHPC IVLRRQCQVN YHARNYHLTP FTIVNIMYSI NKTQGPRALW
160 170 180 190 200
KGMGSTFIVQ GITLGTEGII SEFTPLPREL SHKWNLKQIG GHLLLKGLTH
210 220 230 240 250
VIAMPFYSAS LIETVQSEII RDNPGILDCV KEGIGRVVGM GVPHSKRLLP
260 270 280 290 300
LMVLIFPTAL HGVLHYVISS IVQKLVLLFL KRENSHSLPT ESSTSVQSML
310 320 330 340 350
DAYFPELIAS FAASLCADVM LYPLETVLHR LHIQGTRTII DNTDLGYEVL
360 370 380 390 400
PINTQYEGMR DCINTIKREE GMLGFYKGFG AVVVQYTLHV AVLQLTKIIY

STLLQNVS
Length:408
Mass (Da):44,642
Last modified:November 23, 2004 - v1
Checksum:i4A96EDF538111C8F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ720821 mRNA. Translation: CAG32480.1.
RefSeqiNP_001007831.1. NM_001007830.1.
UniGeneiGga.44173.

Genome annotation databases

EnsembliENSGALT00000000332; ENSGALP00000000331; ENSGALG00000000253.
GeneIDi415610.
KEGGigga:415610.

Similar proteinsi

Entry informationi

Entry nameiS2546_CHICK
AccessioniPrimary (citable) accession number: Q5ZIG3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: November 23, 2004
Last modified: June 7, 2017
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families