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Reviewed, UniProtKB/Swiss-Prot Q5ZCW1 (LAC1_ORYSJ)

Last modified November 25, 2008. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Putative laccase-1
    EC=1.10.3.2
Alternative name(s):
    Benzenediol:oxygen oxidoreductase 1
    Urishiol oxidase 1
    Diphenol oxidase 1
Gene names
Name: LAC1
Ordered Locus Names: Os01g0374600, LOC_Os01g27700
ORF Names: B1045D11.30, OsJ_001779
OrganismOryza sativa subsp. japonica (Rice)
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

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Protein attributes

Sequence length577 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology.

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General annotation (Comments)

Function

Lignin degradation and detoxification of lignin-derived products By similarity.

Catalytic activity

4 benzenediol + O(2) = 4 benzosemiquinone + 2 H(2)O.

Cofactor

Binds 4 copper ions per monomer By similarity.

Subcellular location

Secreted › extracellular space › apoplastPotential.

Sequence similarities

Belongs to the multicopper oxidase family.

Contains 3 plastocyanin-like domains.

Sequence caution

The sequence EAZ11954.1 differs from that shown. Reason: Erroneous gene model prediction.

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Ontologies

Keywords

   Biological processLignin degradation
   Cellular componentApoplast
Secreted
   DomainRepeat
Signal
   LigandCopper
Metal-binding
   Molecular functionOxidoreductase
   PTMGlycoprotein

Gene Ontology (GO)

   Biological processlignin catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

oxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentapoplast

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functioncopper ion binding

Inferred from electronic annotation. Source: InterPro

laccase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2828 Potential
Chain29 – 577549Putative laccase-1
PRO_0000291886

Regions

Domain37 – 153117Plastocyanin-like 1
Domain163 – 316154Plastocyanin-like 2
Domain442 – 561120Plastocyanin-like 3

Sites

Metal binding871Copper 1 By similarity
Metal binding891Copper 2 By similarity
Metal binding1321Copper 2 By similarity
Metal binding1341Copper 3 By similarity
Metal binding4781Copper 4 By similarity
Metal binding4811Copper 1 By similarity
Metal binding4831Copper 3 By similarity
Metal binding5401Copper 3 By similarity
Metal binding5411Copper 4 By similarity
Metal binding5421Copper 2 By similarity
Metal binding5461Copper 4 By similarity
Metal binding5511Copper 4 By similarity

Amino acid modifications

Glycosylation421N-linked (GlcNAc...) Potential
Glycosylation831N-linked (GlcNAc...) Potential
Glycosylation1151N-linked (GlcNAc...) Potential
Glycosylation2761N-linked (GlcNAc...) Potential
Glycosylation3041N-linked (GlcNAc...) Potential
Glycosylation3821N-linked (GlcNAc...) Potential
Glycosylation4021N-linked (GlcNAc...) Potential

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Sequences

Sequence LengthMass (Da)Tools
Q5ZCW1-1 [UniParc].

Last modified November 23, 2004. Version 1.
Checksum: A803FB6E25D34495

FASTA57764,530
        10         20         30         40         50         60 
MGTAKIPALL WFLLAGLVLA LAVNPAHGAK TRHYDFFITE TNYTRLCHEK SILTVNGQFP 

        70         80         90        100        110        120 
GPTIYARKGD FIIVNVHNNG NKNITIHWHG VDQPRNPWSD GPEFITQCPI RPGGNFTYQV 

       130        140        150        160        170        180 
ILFEEEGTLW WHAHSDFDRA TVHGAIVIHP KRGTTFLFRK LDKEIPWWND DVEHVLDKAK 

       190        200        210        220        230        240 
RIGGDVEPSD TNTINGQPGD MFPLCSRDDT FKVAVQQGNT YLLRVINAGL TNDMFFAIAG 

       250        260        270        280        290        300 
HRLTVVGIDA RYTKPITVDY IMIAPGQTMD VLLKANRTLG SNSRYYMAAR TFITLPVDTI 

       310        320        330        340        350        360 
RFNNSTATAI VEYTDSAVAR PVGPPEFPVL LPAIKDEDAA MAFVKQLRSL GNQDHPVHVP 

       370        380        390        400        410        420 
KQVDEHMLID IDINFLPCDA NNATNKLCEG PQGNRFAASL NNVSFQNPAI DVLDAYYYGS 

       430        440        450        460        470        480 
GRGVYEENFP NKLTVIVNPT GDINGGGPLL TKRGTKVKVL EYGTVVEVVF QDLSIENHPM 

       490        500        510        520        530        540 
HLHGFTFYVV GRGSGTFDER RDPATYNLID PPFQNTVSVP KSSWAAIRFR ADNPGVWFMH 

       550        560        570 
CHFDRHVVWG MDTMFIVKDG KTPQAQMLPR PPNMPEC

« Hide

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References

« Hide 'large scale' references
[1]"The genome sequence and structure of rice chromosome 1."
Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y., Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H., Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M. expand/collapse author list , Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M., Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T., Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S., Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H., Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y., Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S., Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y., Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S., Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H., Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.
Nature 420:312-316(2002) [PubMed: 12447438] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[2]"The map-based sequence of the rice genome."
International rice genome sequencing project (IRGSP)
Nature 436:793-800(2005) [PubMed: 16100779] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[3]"Curated genome annotation of Oryza sativa ssp. japonica and comparative genome analysis with Arabidopsis thaliana."
The rice annotation project (RAP)
Genome Res. 17:175-183(2007) [PubMed: 17210932] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: cv. Nipponbare.
[4]"The genomes of Oryza sativa: a history of duplications."
Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. expand/collapse author list , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
PLoS Biol. 3:266-281(2005) [PubMed: 15685292] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.

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Cross-references

Sequence databases

AP003199 Genomic DNA. Translation: BAD61379.1.
AP008207 Genomic DNA. Translation: BAF04988.1.
CM000138 Genomic DNA. Translation: EAZ11954.1. Sequence problems.
RefSeqNP_001043074.1.
UniGeneOs.72229

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID4325440.
KEGGosa:4325440.

Organism-specific databases

GrameneQ5ZCW1.

Family and domain databases

InterProIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view]
Gene3DG3DSA:2.60.40.420. Cupredoxin. 3 hits.
PfamPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
PROSITEPS00079. MULTICOPPER_OXIDASE1. 1 hit.
PS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameLAC1_ORYSJ
AccessionPrimary (citable) accession number: Q5ZCW1
Secondary accession number(s): A2ZTA7
Entry history
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: November 23, 2004
Last modified: November 25, 2008
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectPPAP (Plant Proteome Annotation Project)

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Relevant documents

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations

UniProtKB secondary accession numbers

Index of UniProtKB secondary accession numbers

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents